Blood Gas Analysis Flashcards

1
Q

What does the body produce to metabolise carbohydrates, fats and proteins?

A

Carbon dioxide and hydrogen (CO2 + H+)

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2
Q

Where is CO2 excreted?

A

The Lungs

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3
Q

Where is hydrogen excreted?

A

The Kidneys

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4
Q

What is carbon dioxide?

A

An acid

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5
Q

What does CO2 and H+ form when binded?

A

H2CO3 = carbonic acid

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6
Q

What is a normal pH range ( cat and dog )

A

DOG 7.35-7.45 CAT: 7.31–7.46

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7
Q

What is the normal range of PCO2 (cat and dog)

A

Dog: 35-45 Cat: 25-37

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8
Q

What is the normal range of HCO3- in cats and dogs?

A

Dog: 20-26 Cats: 14-22

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9
Q

What is the normal range of Base Excess BE?

A

-4-+4

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10
Q

What pH is incompatible with life?

A

6.8-7.9

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11
Q

What are the factors of a respiratory acidosis?

A

Elevated PCO2 (above 45mmHg) and low pH below 7.35

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12
Q

What are the factors of a metabolic acidosis?

A

Low BE (below - 4) and HC03 (below 20) and low pH - below 7.35

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13
Q

What are the factors of a respiratory alkalosis?

A

Increased pH (above 7.45) and decreased pCO2 (below 35mmHg)

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14
Q

What are the factors of a metabolic alkalosis?

A

Increase pH (above 7.45) and an increased HCO3 (above 26) and BE above +4.

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15
Q

What are the causes of a respiratory acidosis and some examples ?

A
Drugs from a GA 
Hypoventilation (accumulation of co2) 
Upper airway obstruction 
Central nervous system trauma 
Pleural space disease (pneumothorax, pleural effusion)
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16
Q

What are the causes of a metabolic acidosis and some examples?

A
An increase of acid production 
e.g DKA 
Renal disease 
Diarrhoea/Vomiting (loss of H+)
Hyperadrenocortisim
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17
Q

What are the causes of a respiratory alkalosis?

A
Reduction of Co2 
Hyperventilation 
Pain 
Fever 
Anxiety
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18
Q

What does a low Pa02 represent?

A

Hypoxaemia?

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19
Q

What is Pa02

A

a reflection of the ability of the lungs to transfer oxygen to the blood

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20
Q

What is the cause of hypoxaemia?

A

Reduced fraction inspired oxygen and ventilation perfusion VQ mismatch

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21
Q

What is a normal Pa02 on room air

A

80-105 mmHg

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22
Q

What does PaCo2 indicate

A

the effectiveness or alveolar ventilation

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23
Q

What does hyperventilation result in?

A

Decreased CO2 - (hypocapnia)

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24
Q

What does hypoventilation result in?

A

Increased CO2 (hypercapnia)

25
What is the A-a gradient?
The measure of the difference in oxygen concertation between the alveoli and the artery. (Alveolar - arterial gradient)
26
What does the A - a gradient determine?
whether there are any problems with how the lungs transfer oxygen to the blood and how severe the problems may be.
27
What equation should be used to figure out the oxygenation and ventilation of a patient on room air?.
When a patient is on room air.
28
What equation gets you the PA02 (partial pressure of O2 in alveoli) with a patient on room air?
= 150 - (1.2x pCO2)
29
What equation gets you the A - a gradient once the PA02 has been established?
PAO2 - PaO2
30
What is PaO2
Partial pressure of arterial oxygen
31
What is PaCO2
Partial pressure of arterial CO2
32
What is FiO2
Fraction inspired O2
33
What is hypoxia
reduced oxygen to the tissues
34
What is hypoxaemia?
reduced oxygen to the blood
35
What equation should be used to figure out the oxygenation and ventilation of a patient on oxygen therapy?
PaO2: FiO2 ratio Fio2 x 5 = PaO2 PaO2 / FiO2 as a decimal = result
36
What is the PaO2 usually on a patient receiving oxygen therapy?
PaO2 is 5 times the FiO2
37
For a patient on room air what is a normal reference range?
under 15
38
For a patient on room air what is a mild reference range?
15-25
39
For a patient on room air what is a moderate reference range?
25-35
40
For a patient on room air what is a severe reference range?
over 35
41
For a patient on oxygen therapy what is a normal reference range?
over 400 mmHg
42
For a patient on oxygen therapy what range suggest a lung injury ?
`200-400 mmHg
43
For a patient on oxygen therapy what suggests Acute respiratory distress syndrome (ARDS)
under 200 mmHg
44
What is an acid in relation to acid-base
A substance that can donate hydrogen H+
45
What is an Acidaemia
A disorder that describes the actual pH of the blood being low.
46
What is an alkalemia
A disorder that describes the actual pH of the blood being high
47
What is an acidosis?
Refers to the PROCESS in the body that results in a decrease of blood pH (increase in acidity)
48
What is an alkalosis?
Refers to the PROCESS in the body that results in an increase of blood pH (decrease in acidity)
49
What is a Base?
a substance that can accept hydrogen ions
50
What is Base Excess?
a measurement used to assess the metabolic contribution to an acidosis or alkalosis. A +ive result suggest a an excess of base(metabolic alkalosis) a -ive result suggests a deficit of base. (metabolic acidosis)
51
What is a buffer?
A system that offers immediate cushioning (buffering) to a sudden change in pH
52
What is Metabolic acid?
body acids that cant be be converted to gas
53
What is an example of a metabolic acid found in the body
lactic acid ketones acetoacetic acid glycolic acic
54
What is pH
Determines the acid base status by measuring hydrogen ions
55
What is a respiratory acid
Carbon dioxide
56
What is the equation to figure out a bicarbonate deficit?
BWT (kg) x 0.3 x BE
57
how much bicarbonate should be administered when treating a bicarbonate deficit? and how long should it be administered?
one quarter of the deficit over 5-10 mins
58
Where is the most common place should you place an arterial catheter?
dorsal pedal artery