Blood clotting Flashcards

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1
Q

what is thrombosis?

A

blood clotting which prevents blood loss when a blood vessel is damaged and prevents the entry of diseases causing microorganisms along with providing the framework for repair.

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2
Q

What is the clotting cascade?

A
  1. when a blood vessel is damaged platelets attach to exposed collagen fibres
  2. Thromboplastin is released and this triggers the conversion of inactive prothrombin (protein) into active thrombin (enzyme). In order for this to occur calcium ions and vitamin K must be present. These are known as clotting factors
  3. Thrombin catalyses the conversion of soluble fibrinogen into insoluble fibrin.
  4. Fibrin forms a network of fibres (mesh in which platelets and red blood cells are trapped to form a blood clot)
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