Blood cells and their immunological & clinical significance - 1 Flashcards
1
Q
blood components
A
- erythrocytes
- leukocytes - phagocytes + lymphocytes
- thrombocytes
- plasma - non cellular
2
Q
erythrocytes function
A
contain Hb which carries O2 from lungs to tissues
3
Q
leukocytes functions
A
- phagocytes - first line of defence by ingesting pathogens
- lymphocytes - secrete antibodies and mediate cellular immunity
4
Q
thrombocytes function
A
prevent bleeding by aiding in clotting
5
Q
plasma functions
A
- transport of cellular components of blood
- transport of nutrients, hormones, proteins
- removal of waste products e.g. urea, lactic acid
6
Q
blood investigations include :
A
- analysis of blood cells - look at cell numbers + proportions
- blood smears - shape & appearance
- analysis of plasma components
7
Q
diagnostic ( what is it & what does it entail? )
A
- diagnosing a medical condition
- evaluating the health of an organ
- identifying certain genetic conditions
8
Q
clinical ( what is it & what does it entail? )
A
- initiating right course of treatment
- choosing health care plan + management
- monitoring progress
- prognosis
9
Q
Analysis of blood cells
analysis of RBC
A
- to find Hb concentration in blood
- to find RBC count
10
Q
Analysis of blood cells
analysis of WBC
A
- to find total WBC count
- to measure % of each WBC or differential count
11
Q
Analysis of blood cells
analysis of platelets
A
- to find platelet numbers
12
Q
importance of RBC smears
A
- investigation of abnormally shapped RBC
- e.g. sickle cell, cellular parasites
13
Q
importance of WBC smears
A
- investigation into WBC types + numbers
- e.g. abnormal lymphoblasts in acute lymphoblastic leukaemia
14
Q
importance of platelet smears
A
- investigation of size, shape, numbers
15
Q
Full blood count (FBC)
A
- overall count of blood cells
- provides differential count
- measures size of blood cells
- measures Hb content in RBC
- used to evaluate health
- screening for blood disorders