blood cells Flashcards

1
Q

most numerous cells

A

erythrocytes

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2
Q

no of erythrocytes in human

A

4-6*10^6 /ul

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3
Q

no of erythrocytes in goat

A

14-16 million/ul

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4
Q

no of erythrocytes in poultry

A

2-3 million/ul

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5
Q

which rbc are nucleated

A

biconvex RBCs of poultry

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6
Q

which family has elliptical rbc

A

camilidae

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7
Q

diameter of rbc

A

7-8um

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8
Q

rbc of variable shape seen in

A

goat(anisocytosis)

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9
Q

mcv expressed in

A

femtolitre

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10
Q

mch expressed in

A

picogram

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11
Q

mchc expressed in

A

percentage

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12
Q

when does erythropoiesis start

A

pre natal life

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13
Q

how long does erythropoiesis last

A

life long

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14
Q

organ of erythropoiesis in
1.pre natal life
2. late fetal life
3. young ones
4. adults

A
  1. yolk sac
  2. liver and spleen
    3.bone marrow of long bones
  3. bone marrow of flat bones
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15
Q

which parts of the body retain the ability to produce rbc

A

liver spleen and thymus in case of defect in bone marrow

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16
Q

precursor of RBCs

A

stem cells or common progenitor cells

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17
Q

erythropoietin-
1. release cause
2. release site
3. target organ

A
  1. hypoxia
    2.kidneys
  2. bone marrow
18
Q

different stages of erythrocyte development

A

erythroblast/rubriblast—–rubricyte—–polychromatic rubricyte—–reticulocyte(has a small amt of nuclear material)—–mature rbc

19
Q

which stage does hb develop in rbc

A

polychromatic rubricyte

20
Q

vitamins required for erythropoiesis

A

sino cobal amine(B12) and folic acid

21
Q

minerals requid for erythropoiesis

A

cobalt and iron(+2)

22
Q

lifespan of horse rbc

A

140 days

23
Q

lifespan of cattle rbc

A

90 days

24
Q

lifespan of human rbc

A

120 days

25
Q

products of hemolysis

A

heme( porphyrin+ fe) and globin

26
Q

components of haemoglobin reutilised

A

fe and globin(amino acids)

27
Q

fate of porphyrin

A

undergoes redox rexn to give bile salts

28
Q

pink colour of hb due to

A

heme component

29
Q

precursor of heme

A

acetyl coa + glycine= delta-aminolevulinic acid

30
Q

how many delta-ALA combine to form what

A

2 combine to form porphyrinogen

31
Q

how many porphyrinogen for a pyrolle ring

A

4

32
Q

haemorrhage causes what anemia

A

hypochromic / microcytic

33
Q

deficiency causes what anemia

A

macrocytic / hypochromic

34
Q

causes of aplastic anemia

A

exposure to x-rays , radiation, drugs,mrtabolites

35
Q

causes of deficiency anemia

A

deficiency of nutrients, CIF and disease like gastritis

36
Q

isotonic solution

A

0.9% NaCl solution

37
Q

what happens to rbc in hypertonic solution

A

crenation( folding of memb)

38
Q

causes of hemolysis

A

sphaerocytosis, sickle cell anemia, thallesemia, protozoan

39
Q

tlc

A

7-10 thousand/ul

40
Q

shape of wbc[

A

amoeboid/ motile

41
Q

organ of leucopoiesis

A

bone marrow

42
Q

site of hemolysis

A

reticuloendothelial organs/ tissue( spleen liver and lymphoid organs)