Blood cells Flashcards
What are the types of blood cells?
Monocyte
- Circulating Pre curser to dendritic cells and macrophages
Macrophage
-Tissue resident around the body, phagocytic and antigen presenting
Dendritic cell
-Differentiate in tissue. Phagocytic and antigen presenting. Travel to lymph node and activate T-cells
Neutrophil
-Circulating cell, highly phagocytic granulocyte
Eosinophil
-Circulating cell, responds to IgE. Degranulate to remove parasites
Basophil
-Circulating granulocyte , very low in numbers
Mast cell
-Tissue resident , source of cytokines and can degranulate
T-lymphocytes
-Helper and cytotoxic, recirculate through lymph nodes, activated by dendritic cells
Natural killer cells
-Innate immune cells which kill infected cells using granules contents
B-lymphocytes
-Produce antibodies as defence
-Activated by T helper cells to produce high affinity antibodies
-Become antibody secreting plasma cells
Fill in the gaps of the hematopoiesis table.
What does this blood smear indicate/symptoms :
headache
dizzy
fatigue
-The image shows an abundance of reticulocytes. You can identify these by the dark purple staining inside the red blood cells which is usually absents in mature erythrocytes.
-With the symptoms and increase in reticulocytes this is indicative of anaemia
What is this patients suffering from?
Chronic Lymphoid Leukaemia
These are mature blast cells that are from the lymphoid lineage. The lower numbers of them suggest this is chronic not accurate
What is this patients suffering from?
Acute Myeloid Leukaemia – There are vastly more leukocytes than you would expect in a normal blood smear. If you look closely at the types you can see some that have the band nucleus and granules which tells you that they are from the myeloid lineage
How do you differentiate a platelet from a erythrocyte in their appearance and function?
