Blood Cell Morphology Flashcards

1
Q

How does the blood maintain homeostasis ?

A
  • acting as a buffer
  • participating in coagulation
  • thermoregulation
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2
Q

What are the 3 main proteins that are part of the blood plasma ?

A
  • albumins
  • globulins
  • fibrinogen
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3
Q

What cells are granulocyte leukocytes and what makes them granulocytes ?

A
  • Neutrophils, eosinophils and basophils
  • Cytoplasm packed with granules
  • Nucleus has 2 or more lobes
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4
Q

What cells are agranulocyte leukocytes and what makes them agranulocytes?

A
  • Lymphocytes and monocytes
  • Cytoplasm have few or no granules
  • Mononuclear
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5
Q

What is the quickest RBC to respond ? (For example whenever you get and inflammation or a bacterial infection)

A

Neutrophils (BOLT OF CELLS)

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6
Q

Neutrophils and eosinophils work on the basis of chemotaxis. What do this mean?

A

They can detect the chemical releases (cytokines) from e.g and infection or inflammation and they will trap the origin of that chemical release to the site
When they are at the site they are also phagocytic

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7
Q

What can the granules in eosinophils release and what is this important for ?

A

Histamine

Allergic response

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8
Q

What is the main role of eosinophils ?

A

Killing parasitic worms or parasitic infections

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9
Q

What WBC is bilobed ?

A

Eosinophils

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10
Q

What can the granules in basophils secrete and what are they needed for ?

A

Heparin (anti-coagulant)

Histamine (vasodilator) - allergic reaction

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11
Q

What type of nucleus do monocytes have?

A

Kidney / U-shaped

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12
Q

When monocytes migrate into the tissue, what do they differentiate into

A

Phagocytic Macrophages

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13
Q

Where is a kupffer cell?

A

A macrophage found in the liver

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14
Q

List the WBC in relative abundance.

A
Neutrophils 
Lymphocytes 
Monocytes 
Eosinophils 
Basophils
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15
Q

How are thrombocytes formed?

A

The megakaryocytes stick an arm into blood vessels in the bone marrow and the flow of blood breaks off fragments of the megakaryocyte

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16
Q

What can a rise in neutrophils be indicative of?

A

Presence of acute bacterial infection

17
Q

What is the stem cells that makes all blood cells during haemopoiesis?

A

Pluripotential Haemopoietic stem cell

18
Q

What are the 2 daughter cells of the hemocytoblast?

A

Common myeloid progenitor

Common lymphoid progenitor

19
Q

What does the common lymphoid progenitor cell form?

A

Plasma cell
B-lymphocyte
T-lymphocyte
Natural killer cell

20
Q

What hormone governs erythropoiesis?

A

Erythropoietin

21
Q

List the stages of erythropoiesis.

A
  1. Proerythroblasts
  2. Early erythroblast
  3. Late erythroblast
  4. Normoblast
  5. Reticulocyte
  6. Erythrocyte
22
Q

What happens the level of erythropoietin released by the kidney in hypoxic conditions ?

A

They level rises