Blood Bank Flashcards
Antigens removed by enzymes
Fya, FYb, M, and N
Most antigenic antigen
D
Next most antigenic antigen
KELL
Bombay genotype
hh
Dosage effect
Rh, Duffy, KIDD, MNS
Dosage effect
stronger with homozygous cells, weaker with heterozygous cells
Type of expression of most blood group antigens
Codominance
Blood group with most “H” antigen left
group O
Blood group with least “H” antigen
A1B
Anamnestic antibody response
secondary response
Most dangerous antibody
Anti-Jka
Acquired B like antigens
only in group A persons
Negative reactions on both forward and reverse ABO testing
Incubate reactions at lower temp
Mixed field agglutination on forward ABO testing
Subgroup A3
Negative reaction with Anti-A and Anti-B, positive reaction with Anti A,B
Subgroup Ax
No antibodies on reverse ABO testing
Elderly patient or chemotherapy
Negative reaction with Anti-A1 lectin
A2
Dolichos Biflorus
Anti-A1 lectin
Ulex Europeus
Anti-H lectin
What do Coombs control cells do?
confirms that AHG has been added and works; confirms adequate cell washing