Blood Bank Flashcards

1
Q

Antigens removed by enzymes

A

Fya, FYb, M, and N

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2
Q

Most antigenic antigen

A

D

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3
Q

Next most antigenic antigen

A

KELL

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4
Q

Bombay genotype

A

hh

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5
Q

Dosage effect

A

Rh, Duffy, KIDD, MNS

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6
Q

Dosage effect

A

stronger with homozygous cells, weaker with heterozygous cells

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7
Q

Type of expression of most blood group antigens

A

Codominance

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8
Q

Blood group with most “H” antigen left

A

group O

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9
Q

Blood group with least “H” antigen

A

A1B

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10
Q

Anamnestic antibody response

A

secondary response

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11
Q

Most dangerous antibody

A

Anti-Jka

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12
Q

Acquired B like antigens

A

only in group A persons

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13
Q

Negative reactions on both forward and reverse ABO testing

A

Incubate reactions at lower temp

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14
Q

Mixed field agglutination on forward ABO testing

A

Subgroup A3

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15
Q

Negative reaction with Anti-A and Anti-B, positive reaction with Anti A,B

A

Subgroup Ax

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16
Q

No antibodies on reverse ABO testing

A

Elderly patient or chemotherapy

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17
Q

Negative reaction with Anti-A1 lectin

A

A2

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18
Q

Dolichos Biflorus

A

Anti-A1 lectin

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19
Q

Ulex Europeus

A

Anti-H lectin

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20
Q

What do Coombs control cells do?

A

confirms that AHG has been added and works; confirms adequate cell washing

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21
Q

All panel cells positive, cord cells negative

A

Anti-I

22
Q

Remove Anti-P1 from serum

A

Add hydatid cyst fluid (contains P1 antigen)

23
Q

Antibody most common in warm autoimmune hemolytic anemia (positive DAT)

A

Anti-e

24
Q

Antibody in paroxysmal cold hemoglobinuria

A

Anti-P

25
Q

Antibody most common in cold agglutinin disease

A

Anti-I

26
Q

Other common cold agglutinins

A

Anti-M and Anti-N

27
Q

High frequency and low frequency antigens

A

Corresponding antibodies are rare

28
Q

Systems with IgG antibodies

A

Rh, KELL, Duffy, KIDD, Anti-s

29
Q

Systems with IgM antibodies

A

LEWIS, P, MNS, Lutheran

30
Q

Antibody that crosses placenta

A

ONLY IgG

31
Q

Positive DAT

A

Autoantibody

32
Q

Separating two antibodies

A

Absorption

33
Q

Removing antibody from red cell

A

Elution

34
Q

Universal RBC donor

A

Group O packed cells

35
Q

Universal plasma donor

A

Group AB plasma

36
Q

Rouleaux

A

Saline Replacement Technique

37
Q

Cold Agglutinin

A

Pre-warm technique

38
Q

Transfusion to increase hemoglobin

A

One unit of packed RBCs will raise hemoglobin by 1.0 to 1.5 gm/dL or 3-4% hematocrit

39
Q

PLT storage

A

RT 22-24 degrees Celsius

40
Q

Blood storage

A

1.0 to 6.0 degrees Celsius

41
Q

Blood shipment temperature

A

1.0 to 10.0 degrees Celsius

42
Q

Time limit to return unit of issued blood

A

30 minutes

43
Q

Storage of FFP and Cryo

A

Minus 18 degrees or colder for one year

44
Q

Transfusing cold agglutinin patient

A

transfuse unit through blood warmer

45
Q

Cyro

A

Treatment for hypofibrinogenemia, Von Willebrands, or TTP

46
Q

FFP

A

Treatment for factor deficiency or reverse Coumadin overdose

47
Q

Irradiated blood

A

Immunosuppressed patients, transplant patients, newborns, transfusion from blood relatives

48
Q

Expiration once unit has been entered

A

24H expiration

49
Q

Patient with Anti-IgA antibodies

A

Never give FFP, give washed RBC’s or frozen RBCs

50
Q

Transfusion of newborns

A

O neg RBCs, CMV negative, irradiated

51
Q

History of Hepatitis in blood donor

A

Lifetime rejection to donate blood