Blood and Circulatory system Flashcards

1
Q

Define Essential hypertension

A

Form of hypertension that by definition has no identifiable secondary cause

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2
Q

What is Agranulocytosis?

A

A deficiency of granulocytes in the blood, causing increased vulnerability to infection

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3
Q

Define Heart murmur

A

Recurring sound heard in the heart through a stethoscope that is usually a sign of disease or damage

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4
Q

What is an Angiography?

A

Radiography of blood or lymph vessels, carried out after introduction of a radiopaque substance

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5
Q

What is an Angioplasty?

A

Surgical repair or unblocking of a blood vessel, especially a coronary artery

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6
Q

Define Fallot’s tetralogy

A

Congenital heart defect characterized by four specific cardiac defects

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7
Q

What is Aortic stenosis?

A

Occurs when the heart’s aortic valve narrows, which reduces or blocks blood flow from your heart into the aorta

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8
Q

What is Aplastic anaemia?

A

Deficiency of all types of blood cells caused by failure of bone marrow production

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9
Q

What is an Arrhythmia?

A

A condition in which the heart beats with an irregular or abnormal rhythm

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10
Q

What is Hypertension?

A

Abnormally high blood pressure

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11
Q

What is Ischaemic heart disease?

A

A disease most often resulting from atherosclerosis, which is a buildup of fatty plaques inside the heart’s arteries

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12
Q

What is an Atrial septal defect?

A

A hole in the heart between the upper chambers

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13
Q

What is Bacterial endocarditis?

A

Inflammation of the inner lining of the heart chambers and valves usually caused by a bacterial infection

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14
Q

What is a Pacemaker?

A

A device for stimulating the heart muscle and regulating its contractions

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15
Q

What is Cardiac ischaemia ?

A

Reduced blood flow in the coronary circulation through the coronary arteries

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16
Q

What is Cardiomyopathy?

A

Chronic disease of the heart muscle

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17
Q

What is Malignant hypertension?

A

Very high blood pressure that typically comes on suddenly and quickly

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18
Q

What is Coronary atherosclerosis?

A

Progressive condition in which plaque builds up in the lining of the coronary arteries

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19
Q

What is Cor pulmonale?

A

Abnormal enlargement of the right side of the heart as a result of disease of the lungs or pulmonary blood vessels

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20
Q

What is Phlebitis?

A

Inflammation of the walls of a vein

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21
Q

What is a Sphygmomanometer?

A

An instrument for measuring blood pressure consisting of an inflatable rubber cuff

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22
Q

What is an embolism?

A

Obstruction of an artery, typically by a blood clot or an air bubble

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23
Q

What is an Endarterectomy?

A

Surgical removal of part of the inner lining of an artery, together with any obstructive deposits

24
Q

What is a Mitral stenosis?

A

Narrowing of the valve between the two left heart chambers

25
What is a Ventricular fibrillation?
An abnormal heart rhythm in which the ventricles of the heart quiver due to disorganized electrical activity
26
Acrocyanosis
A condition marked by bluish or purple colouring of the hands and feet, caused by slow circulation
27
Cerebrovascular accident
Occurs when the supply of blood to the brain is reduced or blocked completely
28
Palpitation
Noticeably rapid, strong or irregular heart beat due to agitation, exertion or illness
29
Aortic incompetence
Occurs when the aortic valve does not close tightly, which leads to a regurgitant flow of blood in the pumping chamber
30
Myocardial infarct
Decreased or complete cessation of blood flow to a portion of the myocardium
31
Sclerosis
Abnormal hardening of body tissue
32
Defibrillation
Stopping fibrillation of the heart by administrating a controlled electric shock to allow restoration of the normal rhythm
33
Thrombosis
Local coagulation or clotting of the blood in a part of the circulatory system
34
Ventricular tachycardia
A heart rhythm problem caused by irregular electrical signals in the lower chambers of the heart
35
Atrial flutter
Abnormal heart rhythm that starts in the atrial chambers of the heart
36
Thrombocytopenia
Deficiency of platelets in the blood
37
Aneurysm
An excessive localised swelling of the wall of an artery
38
Arteriosclerosis
Thickening and hardening of the walls of the arteries, occurring typically in old age
39
Claudication
Pain caused by too little blood flow to muscles during exercise
40
Pericarditis
Inflammation of the pericardium
41
Thrombophlebitis
Inflammation of the wall of a vein with associated thrombosis
42
Embolectomy
Surgical removal of an embolus
43
Portal hypertension
Elevated pressure within the portal system, including the portal vein and the tributary veins that drain into it
44
What is blood composed of?
RBS,WBCs, platelets and plasma
45
What is serum?
Plasma that has been stripped off its clotting factors.
46
What is Plasma?
Plasma usually contains about 90% water, with the remaining 10% made up of ions, proteins, nutrients, wastes, and dissolved gases. The ions, proteins, and other molecules found in plasma are important for maintaining blood pH and osmotic balance, with albumin (the main protein in human plasma) playing a particularly important role. Lipids, such as cholesterol, are also carried in plasma, but must travel with escort proteins because they don’t dissolve in water. Lipids, such as cholesterol, are also carried in plasma, but must travel with escort proteins because they don’t dissolve in water.
47
What are RBCs and name their functions
- erythrocytes, are specialized cells that circulate through the body and deliver oxygen to tissues. - small and biconcave and do not contain mitochondria or a nucleus when mature. - Play a role in transport of carbon dioxide, a waste product, from the tissues back to the lungs. Some of the carbon dioxide binds directly to hemoglobin, and red blood cells also carry an enzyme that converts carbon dioxide into bicarbonate. The bicarbonate dissolves in plasma and is transported to the lungs, where it's converted back into carbon dioxide and released. - average life span of 120 days
48
What happens to old RBCs?
Old or damaged red blood cells are broken down in the liver and spleen, and new ones are produced in the bone marrow. Red blood cell production is controlled by the hormone erythropoietin, which is released by the kidneys in response to low oxygen levels. This negative feedback loop ensures that the number of red blood cells in the body remains relatively constant over time.
49
What are platelets (thrombocytes)?
Thrombocytes, cell fragments involved in blood clotting. They are produced when large cells called megakaryocytes break into pieces, each one making 2000-3000 platelets as it comes apart. Platelets are roughly disc-shaped and small, about 2-4 micrometers in diameter.
50
What happens when the lining of a blood vessel is damaged?
When the lining of a blood vessel is damaged (for instance, if you cut your finger deeply enough for it to bleed), platelets are attracted to the wound site, where they form a sticky plug. The platelets release signals, which not only attract other platelets and make them become sticky, but also activate a signaling cascade that ultimately converts fibrinogen, a water-soluble protein present in blood plasma, into fibrin (a non-water soluble protein). The fibrin forms threads that reinforce the platelet plug, making a clot that prevents further loss of blood.
51
What are the different types of white blood cells (leukocytes)?
White blood cells come in five major types, and these are divided into two different groups, named for their appearance under a microscope. One group, the granulocytes, includes neutrophils, eosinophils, and basophils, all of which have granules in their cytoplasm when stained and viewed on a microscope. The other group, the agranulocytes, includes monocytes and lymphocytes, which do not have granules in the cytoplasm.
52
Where are Red blood cells, white blood cells, and platelet-producing cells all descended from?
A common precursor: a hematopoietic stem cell. A hallmark of stem cells is that they divide asymmetrically. That is, one daughter cell remains a stem cell of the same type, while the other daughter cell acquires a new identity. For hematopoietic stem cells, which are found in the bone marrow, one daughter cell remains a hematopoietic stem cell, while the other goes on to become a different type of stem cell: either a myeloid stem cell or a lymphoid stem cell.
53
How do the myeloid and lymphoid stem cells divide?
The myeloid stem cells and lymphoid stem cells also divide asymmetrically, with their non-stem cell daughters generating the mature cell types of the blood. Myeloid stem cells give rise to red blood cells, platelets, and some types of white blood cells, while lymphoid stem cells give rise to the types of white blood cells classified as lymphocytes.
54
What is cooperative binding?
55
What is acid dissociation?
56
What does a haemoglobin curve show?