Blood Flashcards

1
Q

what are the three cell types found in blood

A

red blood cells (erythrocytes )
white blood cells (leucocytes)
platelets (thrombocytes)

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2
Q

what does the biconcave shape of rbcs allow for

A

rapid gas exchange
bend in narrow capillaries
large surface area
expand to accomodate hypotoni solutions

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3
Q

where are rbcs formed

A

red bone marrow

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4
Q

how are old rbcs removed from circulation

A

MPS system - phagocytic system

breakdown products are recycled

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5
Q

what are the breakdown products of haemoglobin

A

protein (globin)
iron (recycled)
haem - broken down to bilirubin and excreted as bile pigment by liver

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6
Q

erythropoeisis

A

process of rbc formation

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7
Q

erythropoietin

A

produced in kidneys, hormone that is released in response to decreased oxygen in kidneys due to decrease in rbcs (e.g due to injury) and stimulates rbc production on red bone marrow

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8
Q

what happens to rbcs as they develop

A

they reduce in size and lose their nucleus

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9
Q

what happens when CO2 enters rbcs

A

it is converted to carbonic acid by carbonic anhydrase present in rbcs. This acid is unstable so is quickly broken down to bicarbonate and a hydrogen ion.

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10
Q

what are the two types of white blood cells and their further subsets

A

granulocytes - neutrophil, basophil, eosinophil

agranulocytes - monocytes, lymphocytes

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11
Q

how is a persons blood group determined

A

by the presence (or absence) of AB antigens and the rhesus antigen

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