Blood Flashcards
what are the three cell types found in blood
red blood cells (erythrocytes )
white blood cells (leucocytes)
platelets (thrombocytes)
what does the biconcave shape of rbcs allow for
rapid gas exchange
bend in narrow capillaries
large surface area
expand to accomodate hypotoni solutions
where are rbcs formed
red bone marrow
how are old rbcs removed from circulation
MPS system - phagocytic system
breakdown products are recycled
what are the breakdown products of haemoglobin
protein (globin)
iron (recycled)
haem - broken down to bilirubin and excreted as bile pigment by liver
erythropoeisis
process of rbc formation
erythropoietin
produced in kidneys, hormone that is released in response to decreased oxygen in kidneys due to decrease in rbcs (e.g due to injury) and stimulates rbc production on red bone marrow
what happens to rbcs as they develop
they reduce in size and lose their nucleus
what happens when CO2 enters rbcs
it is converted to carbonic acid by carbonic anhydrase present in rbcs. This acid is unstable so is quickly broken down to bicarbonate and a hydrogen ion.
what are the two types of white blood cells and their further subsets
granulocytes - neutrophil, basophil, eosinophil
agranulocytes - monocytes, lymphocytes
how is a persons blood group determined
by the presence (or absence) of AB antigens and the rhesus antigen