Blood Flashcards

1
Q

What is the normal blood volume?

A

Five liters

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2
Q

A major function of the blood is the removal of what?

A

Metabolic Waste

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3
Q

Blood plasma is 90% what?

A

Water

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4
Q

60% of the protein found in blood plasma is found in what?

A

Albumin

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5
Q

What is the major contributor to osmotic pressure?

A

Albumin

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6
Q

____, _____, and ____ are the ‘formed elements’.

A
  1. Erythrocytes
  2. Leukocytes
  3. Thrombocytes
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7
Q

____, or red blood cells, are small cells that are biconcave in shape.

A

Erythrocytes

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8
Q

Erythrocytes major function is to carry the oxygen-binding protein ______.

A

Hemoglobin

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9
Q

Blood Cell formation (____) occurs in the _____.

A

Hematopoiesis; Red Bone Marrow

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10
Q

After a hematopoietic stem cell’s descendent becomes committed to forming red blood cells, it begins to divide rapidly and fills with _____, which will be needed to synthesize hemoglobin.

A

Ribosomes

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11
Q

What happens if there are too few erythrocytes in one’s blood?

A

Tissues will not receive enough oxygen

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12
Q

An insufficient number of functional erythrocytes in the blood is called what?

A

Anemia

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13
Q

An excess number of erythrocytes in the blood is called what?

A

Polycythemia

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14
Q

Iron is required in the diet because it is needed to make what?

A

heme

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15
Q

As erythrocytes become old and damaged, they tend to become trapped in the smallest capillaries of the _____, where they are destroyed by _____. (This also occurs to a lesser extent in the liver and in bone marrow.)

A

Spleen; Macrophages

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16
Q

Bilirubin is yellow, and if heme breakdown is excessive or if its excretion is impaired, the result is _____, a visible yellowing of the skin, whites of the eyes, etc.

A

Jaundice

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17
Q

There are three types of granulocyte: _____, _____, and _____.

A
  1. Neutrophils
  2. Basophils
  3. Eosinophils
18
Q

There are two types of agranulocyte: _____ and _____.

A

Lymphocytes; monocytes

19
Q

The most common type of leukocyte are ____.

A

Neutrophils

20
Q

The main function of neutrophils is to what?

A

Kill bacteria

21
Q

Eosinophils are found in large numbers in the columnar epithelia of the _____, _____, and _____, where they guard against entry of foreign invaders into the body.

A

skin, lung, and GI tract

22
Q

The two least common leukocytes in blood are the _____ and _____, which together account for less than 4% of all leukocytes.

A

Basophils; Eosinophils

23
Q

Basophils release _____, which dilates blood vessels (and attracts other leukocytes) so that the immune system can reach and attack an invading organism.

24
Q

__ ______ are agranulocytes which directly attack viral-infected and tumor cells.

A

T Lymphocytes

25
___ _____ are agranulocytes which differentiate into cells which produce antibodies.
B Lymphocytes
26
_____ are agranulocytes which become _____ ('large eaters'), cells with two important functions: eating invaders and activating lymphocytes so that they too can defend the body.
Monocytes; Macrophages
27
Most blood cells die within days or weeks, but monocytes may live for _____ and some lymphocytes live for _____.
Months; years
28
_____ refers to cancer in which an abnormal white blood cell fails to fully differentiate and begins to divide uncontrollably. Untreated, these cancers are always fatal.
Leukemia
29
Formation of the megakaryocytes involves repeated mitoses of megakaryoblasts without _____.
Cytokinesis
30
_____ literally means 'blood stopping,' and is the formal name for the process which prevents blood loss after injury.
Hemostasis
31
The second response of the body to a break in a blood vessel requires platelets, which ____ __ _____.
Form a plug
32
Vitamin _____, which is made by bacteria in the gut, is needed for the formation of several _____ and so is essential if blood is to clot normally.
K; Clotting factors
33
The final, major steps in blood clotting are formation of _____, conversion of prothrombin to _____, and the formation of a(n) _____ mesh from fibrinogen in the plasma.
Prothrombin Activator; thrombin; fibrin
34
A deficiency in circulating platelets ('_____'), failure of the liver to synthesize clotting factors, or a genetic defect in one or more of the clotting factors ('_____') all lead to bleeding disorders.
Thrombocytopenia; Hemophilia
35
The _____ blood groups are based on the presence or absence of two types of antigens on the erythrocyte's surface.
ABO
36
_____' means 'glued together.'
Agglutinate
37
The percentage of erythrocytes (by volume) is called the _____.
Hematocrit
38
Blood that has been centrifuged separates into three layers: _____, _____ and _____.
Erythrocytes; the buffy coat; plasma
39
The 'buffy coat' seen in centrifuged blood is composed of _____ ____ ____and _____.
White Blood Cells; platelets
40
Leukocytes and platelets account for less than _____ of the blood's volume: the remainder is _____ (~ 55%) and _____ (~ 45%).
1%; Plasma; Erythrocytes
41
Fetal blood cells form hemoglobin-F, which has a higher affinity for oxygen than adult hemoglobin, hemoglobin-A, allowing fetal blood to ____ ____ from maternal blood.
Accept oxygen