Blood Flashcards
What are the 3 stages of Haemostasis?
Primary
Secondary
Tertiary
What is the Primary level of Haemostasis?
Vasoconstriction after injury
Platelet plug formation
What is the Secondary level of Haemostasis?
Formation of fibrin though coagulation cascade
What is the Tertiary level of Haemostasis?
Fibrinolysis
Formation of plasminogen, then plasma
What is Von Willibrand’s Disease?
Inherited deficiency of Von Willibrand’s factor
Low levels of Von Willibrand’s Factor
Low levels of Factor VIII
How does Von Willibrand’s Factor act?
Mediates platelet adhesion
Mediates platelet aggregation
Carrier of Factor VIII
What is Haemophilia? What are the 2 types?
An inherited condition that causes an individual to have a lack of clotting factors and an increased bleeding tendency
Haemophilia A
Haemophilia B
What clotting factor is affected in Haemophilia A?
Factor VIII
What clotting factor is affected in Haemophilia B?
Factor IX
What does a raised white blood cell count indicate?
Active infection
What does a raised neutrophil count indicate?
Active infection
What does a raised monocyte count indicate?
Linked to an autoimmune disease
What does a raised prothrombin time indicate?
Can be the effect of an anticoagulant
May be caused by liver disease
What does a raised alkaline phosphatase level indicate?
Liver or bone problems
Possibly a past alcoholic
What medications inhibit Factor 10a?
What kind of drugs are these?
Rivaroxiban
Apixaban
Direct Oral Anticoagulants (DOAC)
When taking an anticoagulant (such as rivaroxiban or apixaban), do you make any adjustments to medication when extracting?
Delay the morning dose of medication
At what value of neutrophils should you give antibiotics before treatment?
Anything below 1
What levels do platelets need to be at to be treated in a Hospital Setting?
50
What levels do platelets need to be at to be treated in a Community Care Setting?
100
What indicates Macrocytic Anaemia?
High mean cell volume
What indicates Haematocrit Anaemia?
Low haemoglobin and high mean cell volume
What do you need to check before an extraction if patient is on tegretol?
Bloods
