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Blood Flashcards

1
Q

Ttt of sphyrocytosis anemia…….

A

Partial or total splenoectomy

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2
Q

Ttt of hemolytic anemia (d.t G6PH deficiency is done by………

A

Avoiding oxidants such as :
Food (beans)
Drugs ( primaquine or antimalarial)

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3
Q

Ttt of osteoarthritis

A
  1. Analgesics
  2. Chondrotin and glycosamine

N.B steroids are not used ( because it is not an autoimmune disease)

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4
Q

Rheumatoid heart fever is diagnosed by……

A

ECA antibodies and rheumatoid factors

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5
Q

Urinary tract infection caused by gram negative bacteria such as :

A

E. Cloi
Klebsilla
Pseudomonas
Proteus mirabilis

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6
Q

Pancreatitis diagnosed by………..

A

⬆️Of lipase and amylase

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7
Q

Ttt of Utrinary tract infection by :
1.
2.
3.
4.

A
  1. Carbencillin
  2. Ticarcillin
  3. Cyprofloxacin
  4. Cephalexin
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8
Q

Fresh Frozen plasma contains all plasma ptn and clotting factors (T or F)

Cryoprecipitate contains fibrinogen (T or F)

A

Both are true

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9
Q

Bleeding time influenced by………
Prothrombin time influenced by…….
Clotting time or partial thromboplastin time are influenced by….

A

Aspirin

Warfarin

Heparin

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10
Q

Clopidogrel is used as……..
Dipyridamol action is………….and………… It’s used in ttt of…….that occurs in arteries.

A

Antiplatelet

Vasodilators and antiplatelet
Tt peripheral vascular diseases

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11
Q

Antidote of streptokinase is

A

Tranexamic acid

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12
Q

Burger’s disease is tt by……..

A

Stop smoking

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13
Q

Alteplase does not have antidote (T or F)

A

T

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14
Q

Iron deficiency anemia is tt by:
1.
2.

A
  1. Ferrous gluconate, ferrous sulphate, ferrous fumarate
  2. Parenterally iron (iron isomaltose or iron carboxymaltose)
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15
Q

Anemia of chronic disease is tt by……

A

Treating the underlying cause

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16
Q

Examples of hemolytic anemia are spherocytosis or G6PD deficiency (T or F)

A

True

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17
Q

S.E of primaquine (antimalarial drug) is…….

A

Visual disturbances

Same as Ivabradine and Ethambutol

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18
Q

PNH or morning haematouria is tt associated with………..and……….,but the ttt is done by:
1.
2.

A

Pancytopenia and thrombosis

  1. Eculizumab (anti-C5)
  2. Anticoagulant
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19
Q

Ttt of sickle cell anemia
1.
2.
3.
4.

A
  1. Hydroxy urea or hydroxycarbamide
  2. Treat the crisis by O2, antibiotics, fluids
  3. Blood transfusion
  4. Splenoectomy
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20
Q

Ttt of mild thalassemia by…….
Ttt of severe anemia by…….

A

Folic acid

Blood transfusion

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21
Q

Folic acid defeciency anemia is tt by…….

A

Folic acid supplements

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22
Q

Autoimmune hemolytic anemia and Immune thrombocytopenia purpura are tt by…………

A

Corticosteroids (hydrocortisone and prednisolone)

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23
Q

Ttt of PRV(polycythemia rubra vera) by……….,………&……….

A

Aspirin, venesection& anticancer drugs

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24
Q

Essential thrombocythemia is tt by………..and………

A

Aspirin and anticancer drugs

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25
Gastric lymphoma reversible is tt by...........
PPI Caused by H. Pylori
26
Ttt of nausea and vomiting after chemotherapy done by.........or.........
Ondansetron or dexamethasone
27
S. E of cyclophosphamide(link adjucent guanine) is.........which tt by........and........
Hemorrhagic cystitis (acroline bind with - SH) Tt by fluid and MSNA
28
S.E of methotrexate : 1. 2. 3.
1. Pulmonary fibrosis 2. Teratogenic 3. Megaloblastic anemia
29
S.E of BXR and DNR is..........
Cardiac myopathy
30
S.E of Bleomycin is.......
Pulmonary fibrosis
31
S.E of vincrystine (defect microtubules during M phase) is............
Peripheral neuropathy or neurotoxicity which l.t numbness and paresthesia
32
Hormonal anti-cancer drugs :
Prednisolone (for ALL, CLL, Non-hodging lymphoma) Estrogen Androgen Tamoxifen Flutamide
33
.............act as aromatase inhibitor l.t decrease formation of Estrogen
Anastrazole
34
Biological anti-cancer drugs :
Trastuzumab and Imatinib
35
........act as tyrosine inhibitor, and used in ttt of........
Imatinib CML
36
...........is teratogenic drug that used in multiple myeloma
Thalidone
37
Drugs that cause pulmonary fibrosis 1. 2. 3.
1. Methotrexate 2. Bleomycin 3. Amiodarone
38
Cardiac toxicity is a side effect of : 1. 2. 3.
1. Daunorubicine 2. Doxorubicine 3. Trastuzumab
39
Abciximab is used in........and.........
Acute coronary syndrome and PCI Bleeding is s.e
40
MOA of adalimumab is........... And used in ttt of..........and.......... And its S.E is.............
Anti-TNF Ttt of IBD and Rheumatoid arthritis S.E is ⬇️ immunity
41
IBD is tt by: 1st choice is....... 2nd choice is........ 3rd choice is.......
1sr. Amino salicylate 2nd. Steroids 3rd. Adalimumab
42
Alemtuzumab is used for ttt of.........
Multiple sclerosis
43
Cetuximab act as.............and is used for ttt of.........
Anti epidermal growth factor Tt colorectal cancer
44
RANKL (which stim. osteoclast) is prevented by........
Denosumab It's not DOC in case of Osteoporosis
45
DOC in Osteoporosis is.........
Bisphosphonate (alenodronate or pamidronate)
46
Eculizumab is used in ttt of......
PNH
47
Infliximab is act as........
Anti-TNF
48
Mepolizumab and omalizumab are used in.........
Resistant asthma
49
Natalizumab acts as............... And used in.............
Anti a4 & anti B1 on lymphocytes Used in demylination condition
50
.......used as anti respiratory syncytial virus that cause bronchiolitis
Palivizumab
51
................ acts as anti VEGF, and used in case of........
Ranibizumab Used in macular degeneration
52
......... act as anti CD20, and used in..........,............ &............
Rituximab resistant rheumatoid arthritis, CLL & Non-Hodgkins lymphoma
53
.......... act as anti IL-6, and used in ttt of...........
Tocilizumab Ttt if resistant rheumatoid arthritis
54
........act as anti HER_NEU, and used in case of.......
Trastuzumab Metastasis breast cancer
55
........ acts as antidote of "xaban" family
Andexanet
56
......acts as Anti-IL1, and used in..........and...........
Anakinra Tt rheumatoid arthritis (last DOC) and FMF (2nd DOC after Colchicine)
57
Colchicine is used as DOC in.........,..........,.........
Pseudogout, pericarditis, FMF
58
Calcium blocker that act on sk.m is..........
Dantrolene
59
..........act as multiple Tyrosine kinase inhibitor, and used in.......and.......
Sorafenib Renal cell carcinoma and hepatocellular carcinoma
60
Bacillus calmette guerin is a vaccine of TB used in bladder cancer (T or F)
True
61
........acts as anti proteosome and used in ttt of........
Bartezomib Tt multiple myeloma
62
Drugs that act as glycoprotein 2b 3a receptor inhibitor are: 1. 2. 3.
1. Abciximab 2. Tirofiban 3. Eptifibatide
63
Hyperlipidemia + Gout tt by
Fenofibrate
64
Ttt of Hodgkins lymphoma :
(ABVD) Adriamycin Bleomycin Vincristine Dacarbazine
65
Ttt of Non-Hodgkins lymphoma :
1. Low grade drugs (R-CVP): rituximab Cyclophosphamide Vincristine Prednisolone 2. High grade drugs (R-CHOP) : rituximab Cyclophosphamide Hydroxyuroubincin Oncovin Prednisolone
66
Ttt of symptoms of multiple myeloma is done by........................ And its S.E :
Bisphosphonate (PRAZE dronate) S. E: Irritation of esophagus GIT disturbances Peptic ulcer
67
Drugs of Osteoporosis :
Bisphosphonate and calcitonin
68
Drugs of hypercalcemia :
Bisphosphonate Calcitonin Normal saline Frusemide
69
Ttt of malignant multiple myeloma itself is done by :
1. Bortezimib 2. Thalidomide (inh. tumor angiogenesis) 3. Dexamethasone Lenalidomide instead of thalidomide
70
S.E of thalidomide : Instead of it we use.....
1. Short extremities 2. Venous thrombosis 3. Behcet's syndrome 4. Pulmonary embolism Lenalidomide Both Lenalidomide and thalidomide are C.I in pregnancy
71
Methotrexate is used in
Anti-cancer IBD Rheumatoid arthritis
72
S. E of hydroxychloroquine is....
Retinopathy
73
S. E of slfasalazine
Pancreatitis
74
S. E of antimalarial drugs
Cinchonism, its symptoms : Tinnitus Vomiting Nausea Vertigo Dizziness

Pharmacology (7 decks)

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