β-Blockers Flashcards
1
Q
Action of Bisoprolol
A
β1
2
Q
Action of Atenolol
A
β1
3
Q
Action of Metoprolol
A
β1
4
Q
Action of Labetalol
A
β + α
5
Q
Action of Carvedilol
A
β + α1
6
Q
Action of Propranolol
A
β (+ weak 5-HT antagonist)
7
Q
Action of Sotalol
A
β (+ K+ channel blocker)
8
Q
PPB of Carvedilol (%)
A
98
9
Q
PPB of Propranolol (%)
A
90
10
Q
PPB of Labetalol (%)
A
50
11
Q
PPB of Bisoprolol (%)
A
30
12
Q
PPB of Atenolol (%)
A
16%
13
Q
PPB of Metoprolol (%)
A
12%
14
Q
PPB of Sotalol (%)
A
0%
15
Q
Metabolism of Bisoprolol
A
50% Liver
16
Q
Metabolism of Carvedilol
A
Liver
17
Q
Metabolism of Propranolol
A
Liver
18
Q
Metabolism of Metoprolol
A
Liver
19
Q
Metabolism of Sotalol
A
Renal excretion
20
Q
Metabolism of Atenolol
A
Renal excretion
21
Q
Metabolism of Labetalol
A
Liver
22
Q
PO Bioavailability of Bisoprolol
A
90%
23
Q
PO Bioavailability of Sotalol
A
100%
24
Q
PO Bioavailability of Metoprolol
A
50%
25
PO Bioavailability of Propranolol
25%
26
PO Bioavailability of Labetalol
25%
27
PO Bioavailability of Atenolol
50%
28
PO Bioavailability of Carvedilol
35%
29
T1/2 of Bisoprolol
12h
30
T1/2 of Sotalol
12h
31
T1/2 of Carvedilol
10h
32
T1/2 of Atenolol
7h
33
T1/2 of Metoprolol
7h
34
T1/2 of Labetalol
4h
35
T1/2 of Propranolol
5h
