Benzos

Question 1

Duration of Lorazepam

Answer 1

12-24h

Question 2

Duration of Diazepam

Answer 2

12h

Question 3

Lorazepam is ….. times as potent as Diazepam

Answer 3

10

Question 4

Duration of Midazolam

Answer 4

6h

Question 5

Duration of Clonazepam

Answer 5

12h

Question 6

Duration of Temazepam

Answer 6

8h

Question 7

PPB of Lorazepam

Answer 7

90%

Question 8

PPB of Diazepam

Answer 8

99%

Question 9

PPB of Midazolam

Answer 9

99%

Question 10

PPB of Clonazepam

Answer 10

85%

Question 11

PPB of Temazepam

Answer 11

95%

Question 12

PPB of Chlordiazepoxide

Answer 12

95%

Question 13

PO Bioavailability of Lorazepam

Answer 13

85%

Question 14

PO Bioavailability of Diazepam

Answer 14

75%

Question 15

PO Bioavailability of Midazolam

Answer 15

40%

Question 16

PO Bioavailability of Clonazepam

Answer 16

90%

Question 17

PO Bioavailability of Temazepam

Answer 17

95%

Question 18

PO Bioavailability of Chlordiazepoxide

Answer 18

95%

Question 19

Vd of Lorazepam (L/kg)

Answer 19

1.3

Question 20

All benzos are metaolised by

Answer 20

Liver

Question 21

Vd of Diazepam (L/kg)

Answer 21

1

Question 22

Vd of Midazam (L/kg)

Answer 22

1.77

Question 23

Vd of Clonazepam (L/kg)

Answer 23

3

Question 24

Vd of Temazepam (L/kg)

Answer 24

1.5

Question 25

Vd of Lorazepam (L/kg)

Answer 25

0.5

Question 26

T1/2 of Lorazepam

Answer 26

20h

Question 27

T1/2 of Diazepam

Answer 27

56h

Question 28

T1/2 of Midazolam

Answer 28

2.5h

Question 29

T1/2 of Clonazepam

Answer 29

60h

Question 30

T1/2 of Temazepam

Answer 30

20h

Question 31

T1/2 of Flumazenil

Answer 31

1h
(Note: shorter than most bezos => risk of resedation)

Question 32

PPB of Flumazenil

Answer 32

50%

Question 33

Vd of Flumazenil (L/kg)

Answer 33

1