Block 9 H+S Flashcards
Why is knowing about decision making in medicine important?
- doctors make decisions very often
- need to know the effect their decision has on patients and their families
- An understanding of it can help improve medical practice
What is the nature of decisions in medicine?
- They’re complex
- doctors generally use process of hypothetic-deductive reasoning
- Research evidence can help inform decision making
What goes into evidence based decisions?
- Evidence from research
- Patient preferences
- Clinical expertise
- Available resources
Why do we need Evidence based decision making?
- Increasing medical knowledge
- Limited time to read
- Textbooks etc. often out of date
- Disparity between diagnostic skills and clinical judgement
What is in the chain of infection?
- host
- infectious agent
- reservoir/ environment
- portal of entry
- mode of transmission
What are the different types of research studies and when are each appropriate?
-Cohort studies- prognosis and cause
-Case control studies- cause
-Randomised control trials- treatments, interventions, benefits/ harm, cost effectiveness
-Qualitative approaches- patient perspectives
Systematic reviews- summary of evidence for a specific question
What is the process of evidence based decision making?
- converting need for information into an answerable question
- identifying the best evidence to answer that question
- critically appraise the evidence for validity, impact etc.
- Integrating the critical appraisal with clinical expertise and patient circumstances
What are the reasons for widespread use of antibiotics?
- Increase in global availability
- Uncontrolled sale in many low/ middle income countries
What are some of the causes of antibiotic resistance?
- Use in livestock for growth promotion
- Volume of antibiotics prescribed
- Inappropriate prescribing of antibiotics
- Missing doses/ not finishing dose
- Releasing antibiotics into environment when manufacturing
How can we prevent antibiotic resistance?
- Only taking them when prescribed by doctor
- Completing full prescription
- Not sharing antibiotics
- Only prescribing when needed
- Using more specific antibiotics
What factors influence infection?
- Infectious agents- ability to reproduce, survival, infectivity etc.
- Mode of transmission
- Environment
- Portal of entry- mouth, nose, ears etc.
- Host factors- nutrition, age, smoking etc.
What are the most important infectious diseases in UK?
- Diptheria
- Haemophilus influenza
- Measles
- Mumps
- Poliomyelitis
- Rubella
- Pneumococcal disease
- Tetanus
- Whooping cough
What are the most important infectious diseases in developing countries?
- Pneumonia
- chronic diarrhoea
- Malaria
- HIV
What is surveillance?
Systematic collection, collation and analysis of data and dissemination of the results so that appropriate control measures can be taken
What is the purpose of surveillance?
- Early warning system for impending public health emergencies
- Document the impact of an intervention or track progress towards a goal
- Monitor and clarify the epidemiology of health problems so can prioritise.
Which infectious diseases are associated with exposure to healthcare?
Nosocomial infections:
- UTI
- Pneumonia
- Lower respiratory infections
- Septicaemia
- MRSA
How can we reduce risk of nosocomial infections?
- Prevention- handwashing, surveillance, sterilisation of instruments
- Detection, investigation and control of outbreaks
- Policies to prevent and control infection
What is global health?
- Health of the global population
- Improving health and achieving equality in health for all people worldwide
- Emphasises transnational health issues, determinants and solutions
What is international health?
Health defined by geography (poor nations), problems (infections, water, sanitation), instruments and a donor- recipient relationship
What are the major functions of global health?
-To provide health-related public goods - research, standards, guidelines
- To manage cross-national externalities through epidemiological surveillance,
information sharing, and coordination
- To mobilise global solidarity for populations facing deprivation and disasters
- To convene stakeholders to reach consensus on key issues, setting priorities,
negotiating rules, facilitating mutual accountability, and advocating for health in other policy-making arenas
What is the motivation for global health?
- Increased awareness of global health disparities
- Enthusiasm to make a difference across international boundaries
What is the 90/10 gap?
Less than 10% of worldwide resources devoted to health research were put towards health in developing countries, where over 90% of all preventable deaths worldwide occurred
What is the solution for this gap?
- Regulation of the quality of imported food, medicines, manufactured goods, and inputs
- Getting timely access to information about the global spread of infectious diseases
- Procurement of sufficient vaccine and drug supplies in a pandemic
- Ensuring a sufficient corps of well-trained health personnel
What impact has travel and migration had on diseases seen in the UK?
- Help spread infectious diseases
- Transmission of behaviour and culture increases risk of non-communicable diseases
- May introduce a diseases to a new population - Widespread and deadly effects
- More in contact with animals - Increase in animal diseases (zoonosis)
- Migrants may bring diseases to countries that have not been exposed
What is WHOs definition of environment, in relation to health?
- All the physical, chemical and biological factors external to a person, and all the related behaviours
- Environmental health consists of preventing or controlling disease, injury, and disability related to the interactions between people and their environment
What is an outbreak?
Sudden increase in occurrences of a disease in a community, which has never experienced the disease before or when causes of the disease occur in numbers greater than expected in a defined area
What is an epidemic?
Occurrence of a group of illnesses of similar nature and derived from a common source, in excess of what would be normally expected in a community or region
What is a pandemic?
- Worldwide epidemic
- Outbreak -> epidemic -> pandemic
How can we prevent epidemics?
-Insure poor countries against the threat of a pandemic
- Funds and international responders sent to country with outbreak to reduce human
suffering
- Development of vaccines
- Fast, early, planned response means less spread
- Monitor disease to prevent future outbreaks
What is the role of WHO in public health?
-Providing leadership on matters critical to health and engaging in partnerships where joint action is needed
- Shaping the research agenda and stimulating the generation, translation, and dissemination of valuable knowledge
- Setting norms and standards and promoting and monitoring their implementation
- Articulating ethical and evidence-based policy options
- Providing technical support, catalysing change, and building sustainable institutional
capacity
- Monitoring the health situation and assessing health trends
What are the determinants of effective outcomes of intervention?
-Econonics - Many developing countries can only spend a few dollars per annum per capita on healthcare
- Priorities - ‘Developed world academic’ analyses of cost-effectiveness may not reflect the developing world realities
- Setting - Countries where true reductions in incidence and prevalence have occurred (e.g. uganda) may be characterised by openness in political leadership towards HIV/AIDS and other cultural factors
What are the public health objectives of vaccination?
-To reduce mortality and morbidity from vaccine preventable infections
- To prevent outbreaks and epidemics
- To contain an infection in a population
- To reduce the number of infections
- To interrupt transmission to humans
To generate herd immunity
- To eradicate an infectious agent
What factors influence the utility of immunisation/vaccination as an approach to disease prevention?
- Disease burden
Risk of exposure to the disease
- Age, health status, vaccination history
- Special risk factors
- Reactions to previous vaccine doses, allergies
- Risk of infecting others
Cost
- Are there other ways to control the disease?
- impact on public perception
What is required for a disease to be eradicated using vaccination?
-Where no other reservoirs of the infection exist in animals or environment
- Where consequences of infection are very high
- Where scientific and political prioritisation exists
Give examples of diseases that have been eradicated?
- Smallpox
- Polio
What is herd immunity?
- Level of immunity in the population which protects the whole population
- Herd immunity only applies to diseases which are passes from person to person
- Provides indirect protection to unvaccinated as well as direct effect to the vaccinated
- A disease can therefore be eradicated even if some people remain susceptible