Block 12 H + S Flashcards
What is the importance of research-informed practice?
-Personal experience is biased in various ways
- Research reports findings for more patients than can hope to see in personal
experience
- Research involves the application of scientific method - Testing of hypotheses,
systematic data collection, analysis-designed to minimise bias
- Recommendations have been assessed for their clinical and cost effectiveness for
the NHS
What is the research cycle?
- Identify a clinical problem
- Basic research - Laboratory based
- Applied (clinical) research
- Clinical care
What is the implementation gap?
Gap between scientific understanding and patient care
What are the barriers to implementation of research-informed practice
-Characteristics of the recommendations - Easy to follow, compatible with existing norms, need for new skills, complexity of recommendations
- Characteristics of the adopters - Knowledge, attitudes, skills and abilities
-Characteristics of the organisation - Limitations and constraints, organisational
culture
-Characteristics of the environment - Social influence
What is quality improvement (QI)?
Facilitate the uptake and continuing use of evidence-based policy and practice, focusing on recurrent problems within system of care to improve:
- Performance
- Professional development
- Service-user outcomes
What does quality improvement involve?
-Engage participants across organisational levels
-Foster environment where improvement and innovation are viewed as normal
- Empowering staff to strive for change
- Provide knowledge and methods to implement change
-Remove barriers to change
Give some examples of QI initiatives?
-Revision of professional roles
Introduction of MDTs
- Change in skill mix, or in the setting of service
-Facilitate audit and benchmarking cycles to identify variations in practice and
outcomes that may be targets for QI efforts
- Network recognition for high-quality practice
-Promote inter-institutional communication and collaberation (and inter-institutioanl
competition)
What makes a QI initiative effective?
-Passive dissemination of information, such as distribution of educational materials or didactic lectures, is generally ineffective in driving change
- Mutlifaceted interventions that act of different levels of barriers to change are more likely to achieve improvements in policy and practice
- Key - Tailored to the key barriers, not just ‘the usual approach’
What is quality and outcomes framework (QOF)?
-Annual reward and incentive programme detailing GP practice achievement results
- Enables commissioners to reward excellence across key domains
- Aims to improve standards of care by assessing and benchmarking the quality of care
patients receive - Compares delivery and quality of care against previous years
Does QOF work?
-Improvements associated with financial incentives seem to be achieved at the expense of small detrimental effects on aspects of care that were not incentivised
- Following the removal of incentives, level of performance across a range of clinical
activities generally remain stable
What was the aims of national CQUINs 2014-15?
- Friends and family test - Incentivise high performing providers
- Improvement against the NHS safety thermometer, particularly pressure ulcers
- Improving dementia and delirium care
- Improving diagnosis in mental health
What is the incidence of falls in the elderly?
-35% of 65-79 year olds
- 45% of 80-89 year olds
-55% of 90+ year olds
What are the possible consequences of falls?
-Osteoporotic fractures - Head injuries - Contusions, lacerations - Psychological problem - Fear of falling, social isolation, depression - Increase in dependence and disability - Impact on carers - Time and anxiety - Institutionalisation
What are the risk factors for falls?
-Muscle weakness
- History of falls
- Gait deficit
- Balance deficit
- Visual deficit
-Arthritis
- Impaired activities of daily living (ADL)
- Cognitive impairment
- Age - >80 years
- Medical conditions - PD, stroke, hypotension, depression, epilepsy, dementia,
arthritis, peripheral neuropathy, dizziness and vertigo
How can falls be prevented/decrease risk?
-Increase activity - Diversity of physical activity -Weekly walk for exercise - Strong family networks - Multifactoral falls risk assessment - Multifactoral intervention - Education and information
What doesn’t help to reduce falls?
-Brisk walking
- Residential care setting - Increases!
- High intensity strength training - Increases injury
- Educational and behavioural alone
What is QALY?
- Quality Adjusted Life Year
- 1 QALY = 1 year in perfect health
- E.g. if an illness reduces quality of life by 20% (0.2) and this affects 10 people then 2 QALY are lost
What is the cost of falls?
£1.3 billion
What is the cost of hip fractures?
- £12k per patient
- Around £720 million per year
What is a common fracture in elderly people?
Fracture of the neck of femur
What are the two types of fracture of the neck of femur?
-Extracapsular - The bone outside the joint capsule breaks Sliding hip screw, intramedullary nail
- Intracapsular - The bone within the joint capsule breaks Internal fixation - Screws, nails, plates and rods
What is avascular necrosis?
- Death of bone tissue due to lack of blood supply
- Can lead to tiny breaks in the bone and the bone’s eventual collapse
What is the main risk factor associated with increased risk of fracture?
Osteoporosis
What are risk factors for hip fractures?
-Low bone mineral density (BMD) is associated with increased fracture riskAge - -Every 5 year increase doubles the risk
- Female gender
- Low body weight (correlates with bone density)
- Family history of hip fracture
- Prior history of fracture
- Smoking
- Ethnicity - Afrocarribeans have very low fracture risk
- Corticosteroid use
- Medications e.g. psychotripic drugs
How can hip fractures be prevented?
- Fall prevention
- Bone protection - Medication, hip protection
What is primary prevention?
Avoidance of disease before any signs or symptoms develop
What is secondary prevention?
Avoidance of progression or later problems, signs or symptoms present
What would be primary and secondary prevention in relation to stroke?
- Primary - No history of stroke or TIA
- Secondary - After either of these have occurred
What is the prevention paradox?
- The majority of people who suffer a stroke are not at high risk of a stroke (e.g. 75% have ‘normal’ blood pressure).
- But if the whole population changes their health behaviour via public health mechanisms, this would lead to a much greater effect.
What are the effects of targeting population for prevention?
-Large potential benefit to community
- Low potential benefit to individual
- May be low perceived benefit to individual
What are the effects of targeting high risk groups for prevention?
-Larger potential benefit to individual
- Smaller effect on population rate of stroke
- Many of the conditions you treat are asymptomatic
- May of the treatments have side effects
Which group of people are at the highest risk from stroke?
-People who have already had one - Secondary prevention reduces risk in these people
- 1/5 people with stroke have another after 3 months
What medication is used for secondary prevention of strokes?
- Ischaemic - Clipidogrel, statin, anti-hypertensive, anticoagulant if AF
- Haemorrhagic - Anti-hypertensives
What percentage of people who have strokes are under 50 years old?
<20%
What is the incidence in strokes in men and women?
- Men are at a 25% higher risk of having a stroke and at a younger age compared to women
- However, as women tend to live longer there are more total incidences of stroke in women
What are the non-modifiable risk factors for strokes?
-Age
- Gender
- Race - South Asians with western lifestyle
- Family history - Rare congenital (in young people - CADASIL)
What are the modifiable risk factors for strokes?
-High blood pressure - Biggest risk factor - Diabetes -Atrial fibrillation -Smoking -Hyperlipidaemia -Obesity
What did the PROGRESS trial show?
Reducing blood pressure after stroke reduces risk of stroke recurrence
What are the barriers for initiating medical therapies for conditions with no obvious
symptoms?
-Misinformed -Not caring -Side effects of tablets - Forgetfulness -Depression - Cognitive impairment
What is a confounding factor?
- Distortion of the relationship between an exposure and outcome due to shared relationship with something else
- Confounders can either increase associated between exposure and outcome, or decrease association between exposure and outcome
How can we limit confounding factors and what are the effects?
Restriction - Limit the participants of your study who have possible cofounders
Means that you have less data and difficult with multiple confounders
- Matching - You create a comparison group that is matched on the possible confounder, make case and control group as similar as possible on the confounder and then ask about exposure status
Used for strong confounders like age and sex
Stratification - Analyse exposure:outcome association in different subgroups of the confounder, recombine data and use a weighted average of the strata
- Limitations - To take into account all confounders would require lots of strata and you may run out of data to fill all possible options in your strata
- Multiple variable regression - You can adjust for the effects of multiple confounders, try and produce a linear model between the outcome and the different exposures
Allows for adjustment of estimates for confounding
What is standardisation?
Way to limit confounding, often used to control for differences in age groups when comparing rates of disease in two populations with different age structures