Block 9 Formative Questions Flashcards
Which specific type of virus causes kaposis sarcoma
Human herpes virus type 8
Difference between dacarbazine and cyclophosphamide (both alkylating agents)
Dacarbazine is a mono functional alkylating agent whilst cyclophosphamide is a bifunctional alkylating agent
Main immune cell involved in formation of acute skin abscess
Neutrophils
What causes glandular fever and its symptoms
Caused by EBV infection. Young adults mostly affected.
Symptoms = fever, sore throat and swollen glands
Diagnostic feature = blood film shows abnormal mononuclear cells/lymphocytes
Which parasite causes dysentery and liver abscesses
Entamoeba histolytica
Which vaccine is given to pregnant women
4 in 1: diphtheria, tetanus, pertussis and polio
Which vaccine is given to infants at the ages of 2, 3, and 4 months of age:
6 in 1 : given three times
Diphtheria, tetanus, pertussis, polio, haemophilus influenzae type B, hep B
The incidence of which cancer has been reduced due to timely screening
Cervical cancer
Use of oral contraceptives is associated with reduced risk of which cancer
Ovarian cancer
Which species of bacteria is usually treated with rifampicin
Effective against both gram positive and negative bacteria.
Inhibits RNA polymerase but only bacterial versions of enzyme
Due to emergence of resistant bacteria it is only used for mycobacterial infections
(Mycobacterium tuberculosis)
Characteristics of caseating necrosis
Complete loss of normal tissue architecture replaced by amorphous, granular and eosinophilic tissue. Varying amounts of fat giving cheese like appearance
Seen in TB
What are the 4 things that can cause an embolism and which is the most common
Air, Amniotic fluid, shrapnel and thrombus
Thrombus most common
A breast cancer is described as being oestrogen receptor positive
More likely to respond to aromatase inhibitor
Aromatase inhibitors = block aromatase enzyme that mediates production of oestrogen
What species causes cellulitis
Cellulitis = infection of deeper skin layers
Most vulnerable place for diabetics is feet
Due to staphylococcus aureus
Influenza A: class and how does it replicate
SS negative strand RNA virus
RNA is transcribed using viral polymerase into a positive sense strand
