Block 4 Cardiology

Question 1

Amiodarone

General MOA and effects

Answer 1

Class III antiarrhythmic agent, which inhibits adrenergic stimulation; affects sodium, potassium, and calcium channels; markedly prolongs action potential and repolarization; decreases AV conduction and sinus node function

Question 2

IV formulation of amiodarone

Answer 2

Nexterone

Question 3

Amiodarone time to onset of action

Answer 3

Onset (PO): Initial response 2 days to 3 wk; peak response takes 1 week to 5 months

Duration (PO): Up to 50 days after discontinuation of therapy

Peak serum time: 3-7 hr (PO)

Question 4

Amiodarone indications

Answer 4

Monomorphic and polymorphic Ventricular Tach
ACLS Pulseless V-fib/V-tach
Ventricular arrhythmias

Question 5

A rhythm that is irregularly irregular and lacks definitive P waves on ECG are an indication of what?

Answer 5

Atrial fibrillation