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Fall Pharm Block 3 > Block 3 Buckets > Flashcards

Block 3 Buckets Flashcards

1
Q

List the drugs in the cross reactivity bucket

A 
PCN with cephalosporins (2-10% chance)
PCN with carbapenams (< 2% chance)
Celacoxib with sulfa drugs
Sulfonylureas with sulfa drugs
Thiazides with sulfa drugs
Loop Diruetcis with sulfa drugs
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2
Q

List the drugs in the “don’t use in pregnancy bucket and state why.

A

Methimazole (Use PTU)
Renin Inhibitors
Neprylisin Inhibitors (Entresto)
Warfarin
Plasminogen Activators
Any NSAID - premature closing of PDA (use APAP)
Misoprostil - stimulates uterine contraction
Tetracyclines - yellow teeth
Fluoroquinolones - soft tissue deformities
Ribavirin - teratogenic

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3
Q

List the drugs in the QD dosing bucket

A

Amlodipine, xarelto, montelukast, oxaprozin, ceftriaxone, fluconazole, emtricitabine, baloxavir

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4
Q

List the drugs in the QT prolongation bucket

A

Methadone, fluoroquinolones, macroliodes, -azoles (except isavuconazole), sotalol, cisapride

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5
Q

List the drugs in the long half-life bucket

A 
Piroxicam (40 - 50h)
Meloxicam (15 - 20h)
Naltrexone
Azithromycin (take for 5 days, lasts about 3 weeks)
Methadone
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6
Q

List the drugs in the “lowers seizure threshold” bucket

A

Contrave
Tramadol
Carbapenems (meropenem lowers it the least)
Meperidine (in renal failure patients)

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7
Q

List the drugs in the hydrophilic bucket.

A

Inhaled corticosteroids
PO Vancomycin
Ampho B
Morphine

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8
Q

List drugs in the “must monitor LFTs” bucket.

A

Diclofenac, -azoles, Allylamines, aectaminophen

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9
Q

List the drugs in the OTC bucket.

A

fluticasone, aspirin, naproxen, ibuprofen, aecetaminophen, terbinafine/naftifine, dextromethorphan, primatine mist (epi), cimetidine, famotidine, nizatidine, ranitidine, omeprazole, esomeprazole, lansoprazole

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10
Q

List drugs in the combination products bucket.

A

Qsymia (phentermine and topiramate)
Contrave (buproprion and naltrexone)
Entresto (sacubitril and valsartan)
Advair diskus (fluticasone and salmeterol)
Arthrotec (diclofenac and misoprostol) - inc gut mucus
Percocet (oxycodone and APAP)
Percodan (oxycodone and aspirin)
Vicodin / Lortab (hydrocodone and APAP)
Augmentin (amoxicillin and clavulonic acid) - PO
Unasyn (ampicillin and sulbactam) - IV
Timentin (ticarcillin and clavulanate) - ES PCN
Zosyn (piperacillin and tazobactam) - ES PCN
Primaxin (imipenem and cilastatin) - dec nephrotoxicity
Ceph-bactam combos - just know they exist
IV Voriconazole - add cyclodextrin to get in sol’n (A/E - inc nephrotoxicity)

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11
Q

List the drugs in the endotracheal tube bucket.

A

naloxone, atropine, lidocaine, epinephrine

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12
Q

List the drugs in the black box warning bucket.

A 
GLP-1 agonists - thyroid tumors
Neprilysin inhibitors (entresto) - fetal toxicity
Itraconazole - CHF, negative inotropy
Fluoroquinolones - tendon rupture
Tigecycline - increases mortality
Cisapride - QT prolongation
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13
Q

List the drugs in the “take on an empty stomach” bucket.

A

Synthroid, Ampilcillin, PCN, PO Itraconazole, Voriconazole

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14
Q

List the drugs in the “covers atypicals” bucket.

A

Macrolides - best

Fluoroquinolones - ok

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15
Q

List the drugs in the chelators bucket.

A

Tetracyclines, Fluoroquinolones, Sucralafate, Baloxavir

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16
Q

List the drugs in the pseudomonas bucket.

A 
Ceftazidime
Cefapime
ES PCNs
Carbapenems EXCEPT ertapenem
Ciprofloxacin (only PO option)
Aminoglycosides (neomycin, gentamycin, tobramycin)
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17
Q

List the drugs in the MRSA bucket

A

Hospital Acquired: Vancomycin, Ceftaroline, Linezolid

Community Acquired: Bactrim, Clindamycin

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18
Q

List the drugs in the ween from opiate use disorder bucket.

A

Naltrexone, Methadone, Buprenorphine

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19
Q

List the drugs in the chlamydia/gonorrhea bucket.

A

Azithromycin and Ceftriaxone
Can choose ceftriaxone and ciprofolxacin
Always order RPR also - test for syphilis

20
Q

List the drugs in the candida coverage bucket.

A 
Fluconazole (except for C Glabrata and Krusei)
Itraconazole
Voriconazole (DOC for aspergillus)
Ampho B
Echinocandins
Flucytosine
21
Q

List the drugs in the cryptococcus bucket.

A

Fluconazole
Ampho B
Flucytosine

22
Q

List the drugs in the histoplasmosis bucket.

A

Itraconazole

Ampho B

23
Q

List the drugs in the aspergillus bucket.

A 
Voriconazole
Posaconazole
Isavuconazole
Ampho B
Echinocandins
24
Q

List the drugs in the mucor bucket.

A

Posaconazole

Isavuconazole

25
Q

List the drugs in the “avoid in children” bucket.

A

Aspirin - Reyes Syndrome
Tetracyclines - yellow teeth
Fluoroquinolones - soft tissue

26
Q

List the drugs in the lethal injection bucket

A

Potassium, Paralytic, Sedative

27
Q

List the drugs in the hepatic encephalopathy bucket

A

Neomycin PO
Lactulose
Rifaximin PO

28
Q

List the drugs in the positive inotrope bucket

A

Digoxin, dobutamine, dopamine, epi, norepi

29
Q

List the effects in the anti-Ach side effects bucket

A 
Constipation
Dry mouth (xerostomia)
Urinary Retention
Sedation
Tachycardia
30
Q

List the drugs in the “beta blockers for CHF” bucket.

A

metoprolol, bisoprolol, carvedilol

31
Q

List the drugs in the “calcium channel blockers for CHF” bucket.

A

amlodipine (best) and nifedipine

32
Q

List the drugs in the prodrug bucket.

A

enalapril –> enalaprilat
valacyclovir –> acyclovir
valganciclovir –> ganciclovir (PO for CMV)

33
Q

List the drugs in the “beta blockers that block alpha 1” bucket.

A

carvedilol and labetalol

34
Q

List the beta blockers in the migraine prophylaxis bucket.

A

atenolol, metoprolol, nadolol, nebivolol, propranolol, timolol

35
Q

List the drugs in the glaucoma bucket.

A

timolol and acetazolamide

36
Q

List the drugs in the ototoxicity bucket.

A

loop diuretics
NSAIDs - piroxicam and ASA
Aminoglycosides

37
Q

List the drugs in the photosensitivity bucket.

A

thiazides - HCTZ and Chydrochlorthiazide

38
Q

List the drugs in the thrombocytopenia bucket.

A

ticlopidine, heparin (HIT), H2 receptor blockers, linezolid

39
Q

List the drugs in the “slow-on, slow-off” bucket.

A

Levothyroxine/Synthroid
Warfarin
Clopidogrel
Proton Pump Inhibitors

40
Q

List the drugs in the OD treatment bucket.

A 
HyperK --> CaCl
Digoxin OD --> digibind
Dabigitran OD --> Praxbind (only NOAC that can be reversed)
Heparin OD --> IV Protamine
Opioid OD --> Naloxone
41
Q

List the drugs in the meningitis bucket.

A

Meningococcal (Nisseria) –> Minocycline
Adult Meningitis –> Ceftriaxone (double dose)
Newborn Meningitis (Listeria) –> Ampicillin
Cryptococcal –> Ampho B (IV) and Flucytosine (PO)

42
Q

List the drugs in the CMV bucket

A 
Acyclovir - not preferred
Valacyclovir - not preferred
Ganciclovir
Valganciclovir - allows for PO treatment
foscarnet - resistant CMV
Cidofovir
43
Q

List the drugs in the “for HIV but also cover HBV” bucket.

A

Lamivudine – BID
Emtricitabine – QD
Tenofovir disoproxil (TDF)
Tenofovir alafenamide (TAF)

44
Q

List the drugs in the live vaccines bucket.

A

MMR, varicella zoster, zostavax (shingles - not hot)

45
Q

List the drugs in the killed vaccines bucket.

A

shingrix (shingles - hot), IPV (polio), influenza, Hep A, Hep B, rabies

46
Q

List the drugs in the covid treatment bucket.

A

remdesivir (only hospitalized patients on O2 - 5 days)
Antibody therapy
Steroids - dexmethasone

47
Q

List the drugs in the covid vaccines bucket.

A

Maderna - antibodies attached to caronavirus spikes

Pfizer - mRNA that programs human cells to make the caronavirus spikes

Fall Pharm Block 3 (8 decks)

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