Block 2 ANS Flashcards
Cholinergic drugs
Medications that inhibit, enhance, or mimic the action of the neurotransmitter ACETYLCHOLINE
Adrenergic drugs
Medications that mimic or interfere with the release or action of NOREPINEPHRINE and EPINEPHRINE
Cholinergic Agonist
Enhance or mimic acetylcholine effects
Cholinergic Antagonist
Block the action of acetylcholine
Adrenergic Agonist
Medications that act on receptors stimulated by norepinephrine or epinephrine
Adrenergic Antagonist
Inhibit the norepinephrine or epinephrine effect at the adrenergic receptors
Carbachol
Relieves intraocular pressure in open angle glaucoma
Direct Cholinergic Agonist
Methacholine
Challenge test for diagnosis of bronchial asthma
Direct Cholinergic Agonist
Pilocarpine
Relieves intraocular pressure in open and closed angle glaucoma. Stimulates sweat, tears, and saliva (Sjogren syndrome)
Direct Cholinergic Agonist
Bethanechol
Activates bladder smooth muscle, urinary retention.
Direct Cholinergic Agonist
Donepezil, Rivastigmine, Galantamine
First line for Alzheimer Disease
Indirect Cholinergic Agonist (Anticholinesterases)
Indirect Cholinergic Agonist
Anticholinesterases, reversible inhibition of acetylcholinesterase ?
Edrophonium
Used for Myathenia Gravis, but replaced by anti-AChR Ab
Indirect Cholinergic Agonist
Neostigmine
Post-operative and neurogenic ileum, reversal of neuromuscular blockage
Indirect Cholinergic Agonist
Pyridostigmine
Myathenia gravis medication
Indirect Cholinergic Agonist
Atropine
Bradycardia, Pupil Dilation
Hot as a Hare Dry as a Bone Blind as a Bat Mad as a Hater Full as a Flask
Antimuscarinic Drug
Albuterol, Salmeterol, Terbutaline
Bronichial asthma, COPD
B2>B1
Direct Adrenergic Agonist
Dobutamine
Heart failure, Cardiogenic shock
B1>B2, alpha stimulation
Direct Adrenergic Agonist
Dopamine
Unstable Bradycardia
D1=D2>B>A stimulation
Direct Adrenergic Agonist
Epinephrine
Anaphylaxis
B>A stimulation
Direct Adrenergic Agonist
Phenylephrine
Hypotension (vasoconstrictor)
a1>a2
Direct Adrenergic Agonist
Amphetamine (methylphenidate)
Norepinephrine reuptake inhibitor and releases stored catecholamines
Narcolepsy, ADHD
Indirect Adrenergic Agonist
Cocaine
Powerful addictive stimulant drug, norepinephrine reuptake inhibitor
Vasoconstriction, hyper tension, coronary vasospasm
Indirect Adrenergic Agonist
a-methyldopa
hypertension in pregnancy
Tizanidine
Relief spasticity
Clonidine
Hypertensive urgency
Phenoxybenzamine
Irreversible a-blocker
Pheochromocytoma (pre-operatively) to prevent catecholamine (hypertensive) crisis
Prazosin, Terazosin, Tamsulosin
treatment of urinary symptoms of Benign Prostatic Hyperplasia
Mirtazapine
Depression
Timolol
Nonselective
Decreases production of aqueous humor (glaucoma)
Propranolol
Hyperthyroidism (decrease HR) and Migraine
Bronchoconstriction, Arrhythmias, Sexual impairment, Metabolic disturbances
Labetalol
Alternative to methyldopa in the treatment of pregnancy- induced hypertension; and hypertensive emergencies
Carvedilol
Stable chronic heart failure
Acebutolol, atenolol, betaxolol, bisoprolol, esmolol, metoprolol
Used in hypertensive pts with imparted pulmonary function; chronic stable angina
Minimizes unwanted chrochoconstriction