Block 14 Cumulative

Question 1

Octretide

Answer 1

GH antagonist

Use: acromegaly/gigantism, hormone secreting tumors, bleeding esophageal varices

Question 2

Lispro

Answer 2

Fast acting meal time insulin

Activates tyrosine kinase to GLUT 4

Question 3

Glargine

Answer 3

Long acting 1 hour to 24 hour basal insulin

No peak

Question 4

Metformin

Answer 4

First line diabetic treatment

Activates AMPK

CI: renal or liver failure, w/ IV contrast

SE: diarrhea and lactic acidosis

Question 5

Sitagliptin

Answer 5

DDP-4 inhibitor

Slows activation of incretin hormones

Question 6

Hydrocortisone

Answer 6

Treat adrenal insufficiency- Addison disease

Question 7

Alendronate

Answer 7

Binds to bone remodeling sires to inhibit osteoclasts

First line OP

Must be able to stand or sit for 30-60 minutes if not use SERM

Question 8

Raloxifene

Answer 8

SERM reduces reabsorption of bone and increase BMD

Do not give if history of thromboembolic events

No risk of breast cancer

Question 9

Spironolactone

Answer 9

Inhibits aldosterone

Conn syndrome

SE: gyneocomastia

Can give w sulfa allergy

Question 10

Finasteride

Answer 10

5a-reductase inhibitor

for BPH, alopecia

SE: decreased libido

Question 11

Sildenafil

Answer 11

erectile dysfunction

SE: increase BP, headache, blurry vision, blue tinted vision

DI: Nitroglycerine, vasodilators

Question 12

Clomiphene

Answer 12

Induces ovulation by blocking estrogen receptors and increasing FSH and LH

SE: nausea, cysts