Block 1 Lecture 5 -- ANS Review

Question 1

What are the components of the peripheral nervous system?

Answer 1

1) somatic ns
2) enteric ns
3) autonomic ns

Question 2

Where is the cell body of an alpha-motor neuron?

Answer 2

ventral horn

Question 3

Where is Ach made in an alpha-motor neuron?

Answer 3

soma, transported to synapse

Question 4

What are the 5 ways to regulate somatic activity (relax muscle)?

Answer 4

1) stop brain signal
2) stop signal in sc
3) post-synaptic receptor
4) nerve terminal
5) cell body

Question 5

Where are the cell bodies in the enteric nervous system?

Answer 5

intramural plexus of the intestinal wall

Question 6

What are the NTs in the enteric nervous system?

Answer 6

serotonin (5-HT)

dopamine

Question 7

What are the NTs in the autonomic nervous system?

Answer 7

Ach
NE
Epi

Question 8

What sweat glands in the sympathetic nervous system use sympathetic adrenergic receptors?

Answer 8

Apocrine

piloerection

Question 9

What sweat glands in the sympathetic nervous system use muscarinic receptors?

Answer 9

Eccrine

Question 10

What are characteristics of sympathetic nervous system?

Answer 10

1) thoracolumbar chain (short pre-ganglionic neurons)
2) diverse (ramified) connectivity
3) coordinated organ regulation

Question 11

MoA of ondansetron?

Answer 11

5-HT3 antagonist

– acts on 5-HT3 receptors locally (in gut) and centrally (CTZ in area postrema of brainstem)

Question 12

What is the CTZ?

Answer 12

Chemotactic Trigger Zone (vomiting reflex)

Question 13

What are characteristics of the parasympathetic nervous system?

Answer 13

1) craniosacral; long-preganglionic
2) independent organ regulation
3) specific connectivity

Question 14

What does SLUDGE stand for?

Answer 14

1) salivation
2) lacrimation
3) urination
4) decreased HR
5) gastric emptying
6) emesis

Question 15

Which autonomic system is essential for life?

Answer 15

parasympathetic

Question 16

What is the function of the PNS?

Answer 16

conservation of energy, maintenance of organ

Question 17

Fx of beta-1 in heart

Answer 17

SA: increase HR
atria: increase FOC and CV

Question 18

Fx of M2 in heart

Answer 18

SA: decrease HR

Question 19

Function of b2 in vsm?

Answer 19

dilation for skeletal muscle, lung, liver

Question 20

Function of a1 in vsm?

Answer 20

constriction for skin and visceral organs

Question 21

Fx of b2 in lung

Answer 21

relax bronchiole sm

Question 22

Fx of a1 in lung

Answer 22

decreases bronchiole secretions

Question 23

Fx of M3 in lung

Answer 23

increase in secretions

slight contraction of bronchiole sm

Question 24

Fx of b2 in GI

Answer 24

relaxes sm

Question 25

Fx of a1 in GI

Answer 25

contract sphincters | decrease secretions

Question 26

Fx of M1/M3 in GI

Answer 26

increase secretion, motility, tone (1 and 3)

Question 27

Fx of M2 in GI

Answer 27

relax sm of sphincters

Question 28

Fx of a1 in eye re: pupil size

Answer 28

contraction of radial muscle to increase pupil size

Question 29

Medical term for dilation

Answer 29

mydriasis

Question 30

Medical term for pupil constriction

Answer 30

miosis

Question 31

Fx of M3 in eye re: pupil size

Answer 31

contraction of circular muscle to reduce pupil size

Question 32

Fx of b2 in eye re: accommodation?

Answer 32

relax ciliary muscle to thin lens for far vision

Question 33

Fx of M3 in eye re: accommodation

Answer 33

contraction of ciliary muscle to thicken lens for near vision

Question 34

Fx of b3 in urinary bladder?

Answer 34

b3 in detrusor | relaxation

Question 35

Fx of a1 in urinary bladder

Answer 35

a1 in sphincters/trigone | contraction

Question 36

Fx of M3 in bladder

Answer 36

M3 in detrusor | contraction

Question 37

Fx of M2 in bladder

Answer 37

M2 on sphincters... | relaxation

Question 38

Fx of b2 in liver

Answer 38

gluconeogenesis, glycogenolysis

Question 39

Fx of b3 on adipocytes

Answer 39

lipolysis, thermogenesis

Question 40

Fx of b2 in skeletal muscle

Answer 40

??? unknown

Question 41

Fx of a1 in sweat glands?

Answer 41

``` piloerection emotional sweating (not thermoreg) in armpits, ear canals, perianal ```

Question 42

Fx of M3 in sweat glands?

Answer 42

cholinergic-mediated SNS end-organ response | -- thermoreg