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PHS 931 > Block 1 Lecture 5 -- ANS Review > Flashcards

Block 1 Lecture 5 -- ANS Review Flashcards

1
Q

What are the components of the peripheral nervous system?

A

1) somatic ns
2) enteric ns
3) autonomic ns

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2
Q

Where is the cell body of an alpha-motor neuron?

A

ventral horn

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3
Q

Where is Ach made in an alpha-motor neuron?

A

soma, transported to synapse

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4
Q

What are the 5 ways to regulate somatic activity (relax muscle)?

A

1) stop brain signal
2) stop signal in sc
3) post-synaptic receptor
4) nerve terminal
5) cell body

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5
Q

Where are the cell bodies in the enteric nervous system?

A

intramural plexus of the intestinal wall

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6
Q

What are the NTs in the enteric nervous system?

A

serotonin (5-HT)

dopamine

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7
Q

What are the NTs in the autonomic nervous system?

A

Ach
NE
Epi

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8
Q

What sweat glands in the sympathetic nervous system use sympathetic adrenergic receptors?

A

Apocrine

piloerection

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9
Q

What sweat glands in the sympathetic nervous system use muscarinic receptors?

A

Eccrine

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10
Q

What are characteristics of sympathetic nervous system?

A

1) thoracolumbar chain (short pre-ganglionic neurons)
2) diverse (ramified) connectivity
3) coordinated organ regulation

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11
Q

MoA of ondansetron?

A

5-HT3 antagonist

– acts on 5-HT3 receptors locally (in gut) and centrally (CTZ in area postrema of brainstem)

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12
Q

What is the CTZ?

A

Chemotactic Trigger Zone (vomiting reflex)

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13
Q

What are characteristics of the parasympathetic nervous system?

A

1) craniosacral; long-preganglionic
2) independent organ regulation
3) specific connectivity

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14
Q

What does SLUDGE stand for?

A

1) salivation
2) lacrimation
3) urination
4) decreased HR
5) gastric emptying
6) emesis

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15
Q

Which autonomic system is essential for life?

A

parasympathetic

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16
Q

What is the function of the PNS?

A

conservation of energy, maintenance of organ

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17
Q

Fx of beta-1 in heart

A

SA: increase HR
atria: increase FOC and CV

18
Q

Fx of M2 in heart

A

SA: decrease HR

19
Q

Function of b2 in vsm?

A

dilation for skeletal muscle, lung, liver

20
Q

Function of a1 in vsm?

A

constriction for skin and visceral organs

21
Q

Fx of b2 in lung

A

relax bronchiole sm

22
Q

Fx of a1 in lung

A

decreases bronchiole secretions

23
Q

Fx of M3 in lung

A

increase in secretions

slight contraction of bronchiole sm

24
Q

Fx of b2 in GI

A

relaxes sm

25
Q

Fx of a1 in GI

A

contract sphincters

decrease secretions

26
Q

Fx of M1/M3 in GI

A

increase secretion, motility, tone (1 and 3)

27
Q

Fx of M2 in GI

A

relax sm of sphincters

28
Q

Fx of a1 in eye re: pupil size

A

contraction of radial muscle to increase pupil size

29
Q

Medical term for dilation

A

mydriasis

30
Q

Medical term for pupil constriction

A

miosis

31
Q

Fx of M3 in eye re: pupil size

A

contraction of circular muscle to reduce pupil size

32
Q

Fx of b2 in eye re: accommodation?

A

relax ciliary muscle to thin lens for far vision

33
Q

Fx of M3 in eye re: accommodation

A

contraction of ciliary muscle to thicken lens for near vision

34
Q

Fx of b3 in urinary bladder?

A

b3 in detrusor

relaxation

35
Q

Fx of a1 in urinary bladder

A

a1 in sphincters/trigone

contraction

36
Q

Fx of M3 in bladder

A

M3 in detrusor

contraction

37
Q

Fx of M2 in bladder

A

M2 on sphincters…

relaxation

38
Q

Fx of b2 in liver

A

gluconeogenesis, glycogenolysis

39
Q

Fx of b3 on adipocytes

A

lipolysis, thermogenesis

40
Q

Fx of b2 in skeletal muscle

A

??? unknown

41
Q

Fx of a1 in sweat glands?

A 
piloerection
emotional sweating (not thermoreg) in armpits, ear canals, perianal
42
Q

Fx of M3 in sweat glands?

A

cholinergic-mediated SNS end-organ response

– thermoreg

PHS 931 (29 decks)

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