blistering disease Flashcards
1
Q
PV
A
desmoglien 3 +/- desmoglien 1, desmocollin 1/2, periplakin
2
Q
PF
A
desmoglien 1
3
Q
PErythematosus
A
desmoglien 1
4
Q
fogo selvagem
A
desmoglien 1
5
Q
pemphigus herpetiformis (clinically DH, path PV)
A
desmoglien 3, desmoglien 1, desmocollin 1/3, and unknown kDA 178 protein
6
Q
drug induced pemphigus
A
desmoglien 1 +/- desmoglien 3
7
Q
IgA pemphigus (includes IEN and SBD)
A
SBD - desmocollin 1
8
Q
paraneoplastic pemphigus
A
plectin, desmoplakins I/II, envoplakin, periplakin, desmoglien 3/1, BP-230
9
Q
bullous pemphigoid
A
BP 230/180 on collagen 17
10
Q
pemphigoid gestationis
A
BP 180
11
Q
LABD
A
LAD-1, LABD97
12
Q
DH
A
transglutaminase 3 (epidermal transglutaminase antibodies)
13
Q
EBA
A
collagen 7
14
Q
bullous SLE
A
collagen 7
15
Q
MMP/CP
A
BP 230, BP 180, laminin 332, laminin gamma or alpha 6/beta 4 integrin
- ** alpha 6 integrin –> oral MMP
- **beta 4 integrin –> ocular MMP and/or multisite MMP
- **BP 180, laminin 332 –> multisite MMP, increased risk of cancer specifically colon, stomach, breast, lung
