Bleeding Disorders Flashcards
1
Q
What causes essential thrombocytopenia?
A
Overproduction of platelets by megakaryocytes in BM. Myloproliferative disorder
2
Q
Is essential thrombocytopenia bar-abl positive?
A
No
3
Q
What is the median age of ET
A
50
4
Q
What is erythrometagia and what bleeding disorder is it associated with?
A
ET
5
Q
Transitory visual or hearing defects are associated with what bleeding disorder
A
ET
6
Q
Risk of thrombosis is increased in patients with ET if it is accompanied by two features. What are they?
A
Jak2 mutation (V615F in 50%)and high wbc
