Bleeding

Question 1

Describe the features of hereditary hemorrhagic teleangiectasia.

Answer 1

autosomal dominant bleeding disorder, multiple dilated capillaries of skin and mucous membranes, lesions blanch with pressure, arteriovenous fistulas of the lung, liver and brain- risk of abscesses, bleeding from mouth, dental work needs to be atrumatic, antibiotic prophylaxis may be indicated with AV fistulas

Question 2

What effects does liver disease have on bleeding?

Answer 2

diminished absorption of fat soluble vitamins (ADEK) and vitamin K is needed for production of some coagulation factors, the liver also produces all coagulation factors except VIII and possibly XIII