Black & White Pathology Flashcards

1
Q

What is an area of hematopoietic bone marrow that produces a radiolucency, typically in the posterior mandible?

A

Focal Osteoporotic Marrow Defect

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2
Q

What are the characteristics of benign neoplasms of bone?

A
  1. asymptomatic
  2. slow growth
  3. expands the cortex instead of going through it
  4. symmetrical
  5. does not metastasize
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3
Q

What are characteristic of malignant neoplasms of bone?

A
  1. symptomatic
  2. grows faster
  3. invades/destroys structures like the cortex
  4. asymmetrical
  5. poorly defined margins
  6. deposits bone outside of cortex
  7. can metastasize
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4
Q

This is a benign (non-neoplastic) radiographic finding in a female. These are usually seen in the posterior mandible. Dx?

A

focal osteoporotic marrow defect

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5
Q

if this were a focal osteoporotic marrow defect, what would be your next step?

A

Incisional biopsy is necessary to get definitive dx

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6
Q

Don’t really know why this is here but what do you think it is?

A

Idiopathic osteosclerosis

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7
Q

What is an area of radiodensity with unknown cause and cannot be identified as anything else?

A

idiopathic osteosclerosis

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8
Q

New patient that hasn’t had an infection there. Dx?

A

idiopathic osteosclerosis

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9
Q

What is your possible differential dx?

A
  1. Condensing osteitis: associated with an infection
  2. Idiopathic osteosclerosis: unknown cause
  3. Focal cemento-osseous dysplasia: will have a radiolucent rim
  4. Cementoblastoma: fused with the tooth

*bolded pathology is definitive dx

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10
Q

Tooth has Hx of infection. Dx?

A

condensing osteitis

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11
Q

What is an asymptomatic radiolucent lesion that is usually seen crossing the midline of the mandible?

A

Central giant cell granuloma

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12
Q

What radiolucent lesion is usually seen in the posterior mandible of women?

A

Focal osteoporotic marrow defect

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13
Q

What lesion is usually seen across the anterior/midline of the mandible in women?

A

central giant cell granuloma

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14
Q

Female patient. Non-neoplastic lesion. Dx?

A

Central Giant Cell Granuloma

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15
Q

What is your differential? Female patient. Asymptomatic.

A
  1. Central Giant Cell Granuloma
  2. Brown Tumor (of hyperparathyroidism)
  3. Aneurysmal Bone Cyst
  4. Odontogenic Keratocyst
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16
Q

Upturned eyes and big, plump cheeks. Dx?

A

Cherubism

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17
Q

What syndrome features odontogenic keratocysts?

A

Gorlin Syndrome

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18
Q

What is your differential dx?

A
  1. odontogenic keratocyst
  2. aneurysmal bone cyst
  3. traumatic bone cyst
  4. Brown’s tumor
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19
Q

Pt recently experienced trauma. What’s your dx?

A

traumatic bone cyst (AKA simple bone cyst)

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20
Q

What radiographic feature is suggestive of traumatic bone cysts?

A

Scalloping of bone between the roots

21
Q

Dx?

A

Traumatic bone cyst

22
Q

What is your differential?

A
  1. Odontogenic keratocyst
  2. Traumatic bone cyst
  3. Aneurysmal bone cyst
  4. Ameloblastoma

*bolded pathology is definitive

23
Q

What is an intraosseous blood-filled cavity surrounded by connective tissue lining?

A

Aneurysmal bone cyst

24
Q

Why is an aneurysmal bone cyst not a true cyst?

A

It doesn’t have an epithelial lining. (lined by connective tissue)

25
Q

What are three examples of benign fibro-osseous lesions?

A
  1. fibrous dysplasia
  2. cemento-osseous dysplasia
  3. ossifying fibroma
26
Q

Fine, ground glass appearance. Dx?

A

Fibrous dysplasia

27
Q

What two syndrome are associated with polyostotic fibrous dysplasia?

A
  1. McCune-Albright syndrome
  2. Jaffe-Lichtenstein syndrome
28
Q

What is the most common fibro-osseous lesion encountered in clinical practice?

A

Cemento-osseous dysplasia

29
Q

Dx?

A

Focal Cemento-Osseous Dysplasia

30
Q

Lesion later calcifies. Dx?

A

Focal cemento-osseous dysplasia

31
Q

Dx?

A

Focal cemento-osseous dysplasia

32
Q

Asymptomatic teeth that test vital. Dx?

A

Periapical Cemento-Osseous Dysplasia

33
Q

Dx?

A

Periapical cemento-osseous dysplasia

34
Q

Dx? How do these lesions appear in early stages and late stages?

A

Dx: periapical cemento-osseous dysplasia

Early: radiolucent lesion

Late: radiodense lesion with radiolucent rim

35
Q

Usually, occurs in the posterior mandible of women. Dx?

A

Florid cemento-osseous dysplasia

36
Q

Differential dx?

A
  1. Florid cemento-osseous dysplasia
  2. Odontogenic keratocyst
  3. Traumatic bone cyst

*bolded pathology is definitive

37
Q

What are the demographics of florid cemento-osseous dysplasia?

A

90% women, 90% black

38
Q

Are men or women more likely to have cemento-osseous dysplasia?

A

90% women

39
Q

These fibro-osseous lesions will expand the inferior cortex of the mandible. Dx?

A

ossifying fibroma

40
Q

Is ossifying fibroma more likley in males/females and mandible/maxilla?

A

F>M

Md > Mx

41
Q

Usually, these lesions are mixed RO/RL. The inferior border in expanding. Dx?

A

ossifying fibroma

42
Q

These mixed RO/RL lesions are usually seen in women and in the mandible, but this time. Dx?

A

ossifying fibroma

43
Q

Outline of root is obscured. Dx?

A

Cementoblastoma

44
Q

What is your differential?

A
  1. Cementoblastoma: cannot see normal shape of tooth
  2. Condensing osteitis: follows infection
  3. Idiopathic osteosclerosis: unknown cause
  4. Focal cemento-osseous dysplasia: starts as purely RO lesion

*bolded is definitive dx

45
Q

25% of the time these present with a sunburst appearance.

A

osteosarcoma

46
Q

What is the most common malignancy to originate in the bone?

A

osteosarcoma

47
Q

Pt has pain, unilateral swelling of the face, and moth eaten bone upon radiograph. Provisional dx?

A

osteosarcoma

48
Q

What is the most common cancer involving bone?

A

Metastatic tumor of the bone