Biopsy Principles Flashcards
A circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to 1cm (.5 inch) is called?
Papule
A circumscribed change in the color of skin that is neither raised nor depressed is called?
Macule
*Macules are completely flat and can only be appreciated by visual inspection and not by touch. Greater than 1 cm may be called a patch
A raised solid lesion more than 1 cm is called?
Nodule
A solid, raised, flat-topped lesion greater than 1 cm. in diameter is called?
Plaque
*analogous to the geological plateau
A raised lesion less than 1 cm. in diameter that is filled with clear fluid is called?
Vesicle
A circumscribed fluid-filled lesion that is greater than 1 cm. in diameter is called?
Bullae
Being attached directly by its base without a stalk or peduncle is called what?
Sessile
What are the three main choices for a lesion?
1-Watch it (2 weeks)
2-Brush biopsy
3-Soft Tissue scalpel biopsy
When is a brush biopsy indicated?
- White or red spots, chronic ulcerations, mucosal lesions with an abnormal epithelial surface
- Common, small, benign looking abnormalities that have been routinely watched and not suspicious enough to warrant referral for biopsy - “watched”
What are the three possible results from brush biopsy?
1-Negative- no abnormalities
2-Positive- evidence of epithelial dysplasia and/or carcinoma
3-Atypical-abnormal warranting investigation
When is scalpel biopsy indicated?
- Whenever a recognized premalignant lesion is encountered
- Lesion that fails to respond to therapy
________ biopsy removes a portion of the lesion whereas _______ biopsy removes most/all of the lesion
Incisional
Excisional
