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PSYC 475 > Bipolar Drugs - Essential Drugs for Exam 1 > Flashcards

Bipolar Drugs - Essential Drugs for Exam 1 Flashcards

1
Q

Valproate (Depakote, Depakene, Stavzor)

A
  • Better for mixed episodes than lithium
  • Teratogenic
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2
Q

Carbamazepine (Tegretol)

A

Leucopenia + agranulocytosis

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3
Q

Oxcarbazepine

A

Better safety index (no GI issues, doesn’t affect liver enzymes, no leucopenia)

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4
Q

Gabapentin (Neurontin) / Pregabalin (Lyrica)

A

Excellent safety profile (not metabolized by liver, excreted intact)

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5
Q

Topiramate (Topamax)

A
  • Not useful in treatment for BPD
  • Induces weight loss, can counteract weight gain seen in other drugs
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6
Q

Lurasidone (Latuda)

A
  • Atypical antipsychotic
  • Treats adults and pediatric patients (10-17)
  • Antagonist at D2 receptors and 5-HT2A/7 receptors
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7
Q

Quetiapine (Seroquel)

A
  • Issues with off label use in treating insomnia
  • Caused cataracts in Beagles
  • Takes several days/weeks to get an appropriate dose and for symptoms to start improving
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8
Q

Lamotrigine (Lamictal)

A
  • Only mood stabilizer lifting depression than suppressing mania
  • Serious side effect: Stevens-Johnson syndrome (serious rash)
  • Avoid spicy foods when taking Lamictal
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PSYC 475 (12 decks)

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