bipolar Flashcards
how may categories are there for the DSM criteria for manic episode
A-D
Describe categories A of manic episode
Abnormally and persistently elevated, expansive, or irritable mood… persistently increased goal-directed activity or energy, lasting at least 1 week… present most of day, nearly every day
describe categories B of manic disorder
B. … plus 3 (or more) of following (4 if mood only irritable) …
Inflated self-esteem or grandiosity
Decreased need for sleep
More talkative than usual or pressure to keep talking
Flight of ideas/subjective experience that thoughts are racing
Distractibility
Increase in goal-directed activity or psychomotor agitation
Excessive involvement in ‘reckless’ activities
what is the criteria of hypomanic episode
A- Describes mood similar to manic episode.
B. … plus 3 (or more; 4 if mood only irritable) of manic episode criteria (category B)
C. Episode associated with unequivocal (uncharacteristic) change in functioning
D. Disturbance in mood/function change observable by others
E. Not severe enough to qualify for manic category C
F. …not attributable to psychological effects of a substance (but can ‘emerge’ during antidepressant treatment)
Major depressive episode (DSM-5) diagnosis?
An episode of MDD within any bipolar disorder is diagnosed in the same way as unipolar MDD
Define Bipolar I DSM 5 criteria
A. Manic criteria A-D for at least one manic episode
The manic episode MAY have preceded or be followed by hypomanic or depressive episodes
B. Occurrence of manic and MDD episode(s) not better explained by schizoaffective disorder/schizophrenia (etc.)
Define Bipolar II DSM 5 criteria
A. Hypomanic criteria A-F for at least one hypomanic episode
AND there MUST be current/past MDD episode
B. There has NEVER been a manic episode
C. The occurrence of hypomanic and major depressive episode(s) not better explained by schizoaffective disorder…
What is bipolar defined as?
It is defined as a brain disorder which causes unusual shifts in a persons, mood, energy and ability to function.
what is the prevalence for bipolar I?
1%
what is the prevalence for bipolar II?
0.5%
What did Edvardsen, et al (2008) suggest about the genetic heritability of bipolar
Bipolar disorder one of most heritable conditions.
As high as 93% in some twin studies
what doesn’t genetics explain in bipolar disorders
mood swings
what neurotransmitters are thought to be associated with bipolar disorder
Norepinephrine, dopamine, and serotonin (high levels in manic)
how are dopamine receptors involved with bipolar
Overly sensitive
what did Manji & Zarate, 2011 (bipolar)
Argued that irregular firing relates to mood disorders.
too quickly-mania
too slowly- depression