bipolar Flashcards

1
Q

how may categories are there for the DSM criteria for manic episode

A

A-D

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2
Q

Describe categories A of manic episode

A

Abnormally and persistently elevated, expansive, or irritable mood… persistently increased goal-directed activity or energy, lasting at least 1 week… present most of day, nearly every day

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3
Q

describe categories B of manic disorder

A

B. … plus 3 (or more) of following (4 if mood only irritable) …
Inflated self-esteem or grandiosity
Decreased need for sleep
More talkative than usual or pressure to keep talking
Flight of ideas/subjective experience that thoughts are racing
Distractibility
Increase in goal-directed activity or psychomotor agitation
Excessive involvement in ‘reckless’ activities

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4
Q

what is the criteria of hypomanic episode

A

A- Describes mood similar to manic episode.
B. … plus 3 (or more; 4 if mood only irritable) of manic episode criteria (category B)
C. Episode associated with unequivocal (uncharacteristic) change in functioning
D. Disturbance in mood/function change observable by others
E. Not severe enough to qualify for manic category C
F. …not attributable to psychological effects of a substance (but can ‘emerge’ during antidepressant treatment)

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5
Q

Major depressive episode (DSM-5) diagnosis?

A

An episode of MDD within any bipolar disorder is diagnosed in the same way as unipolar MDD

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6
Q

Define Bipolar I DSM 5 criteria

A

A. Manic criteria A-D for at least one manic episode
The manic episode MAY have preceded or be followed by hypomanic or depressive episodes
B. Occurrence of manic and MDD episode(s) not better explained by schizoaffective disorder/schizophrenia (etc.)

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7
Q

Define Bipolar II DSM 5 criteria

A

A. Hypomanic criteria A-F for at least one hypomanic episode
AND there MUST be current/past MDD episode
B. There has NEVER been a manic episode
C. The occurrence of hypomanic and major depressive episode(s) not better explained by schizoaffective disorder…

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8
Q

What is bipolar defined as?

A

It is defined as a brain disorder which causes unusual shifts in a persons, mood, energy and ability to function.

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9
Q

what is the prevalence for bipolar I?

A

1%

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10
Q

what is the prevalence for bipolar II?

A

0.5%

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11
Q

What did Edvardsen, et al (2008) suggest about the genetic heritability of bipolar

A

Bipolar disorder one of most heritable conditions.

As high as 93% in some twin studies

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12
Q

what doesn’t genetics explain in bipolar disorders

A

mood swings

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13
Q

what neurotransmitters are thought to be associated with bipolar disorder

A

Norepinephrine, dopamine, and serotonin (high levels in manic)

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14
Q

how are dopamine receptors involved with bipolar

A

Overly sensitive

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15
Q

what did Manji & Zarate, 2011 (bipolar)

A

Argued that irregular firing relates to mood disorders.
too quickly-mania
too slowly- depression

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16
Q

outline the biological explanation of ion activity in bipolar disorder

A

Ions are crucial for relaying messages within neurons
(action involves potassium and sodium ions).
The pace of this activity regulates how often neurons ‘fire’

17
Q

name some potential triggers of bipolar disorder

A
Stressful or distressing events
Childbirth
Relationship breakdown
Money problems
Childhood sexual abuse
18
Q

describe 3 impacts of bipolar disorder

A

University performance
Legal or financial consequences
Repetitive self-harming behaviours

19
Q

unfortunately, suicide attempts are more frequent in bipolar who suggested this?

A

Kessler, Borges, & Walters, 1999

Risk for death by suicide in BP patients 20–30 times higher than general population (Pompili et al., 2013)

20
Q

name some evidence that supports suicide attempts less frequent during mania

A

BP patients more suicide attempts (27%) than MDD pts (18%; Bottlender et al., 2000)