Biosignaling Flashcards
Intracrine
Signal that acts within the cell
Autocrine
Signal that is released and then binds to its own receptors
Juxtacrine
Howdy next door neighbor
Paracrine
Howdy neighbor but not next door neighbor
Cytokines signal via which pathway?
Paracrine
What are the three main kinds of membrane receptors?
Ionchannel Linked, Enzyme Linked, G Protein Coupled
Ion Channel Linked
Ligand gated ion channel like neurotrans
Enzyme linked receptors
Tend to be kinases, know Receptor Tyrosine kinase
What is the structure of a gprotein?
Aplha, Beta, and Gamma (heterotrimeric structure)
True or False: GTP needs to be present to activate g protein pathway
true
IP3 Pathway
Uses IP3 and Ca2+ to activate PKC
cAMP Pathway
Alpha subunit of gprotein interacts with adenylyl cyclase to activate cAMP which activates PKA
True or False: hydrophobic hormones can act on many cells where as protein/ aa cannot
true