biorisk mitigation strategies

Question 1

can be based on either a hazard and/or a threat.

Answer 1

risk

Question 2

object that can cause harm

Answer 2

hazard

Question 3

person who has intent and/or ability to cause harm to other people, animals, and/or the institution

Answer 3

threat

Question 4

likelihood of an event or incident w/ a hazard that has consequence

Answer 4

risk

Question 5

the probability an
event occurring

Answer 5

Likelihood

Question 6

the severity of
an event

Answer 6

Consequence

Question 7

key comoponent of biorisk management

Answer 7

biorisk assessment, biorisk mitigation, performance

Question 8

process of identifying hazards and evaluating risks associated with biological agents and toxins, taking into account the adequazy of any existing controls and deciding whether or not the risks are acceptable

Answer 8

biorisk assessment

Question 9

actions and control measures that are put into place to reduce or eliminate the risks associated with biological agents and toxins

Answer 9

biorisk mitigation

Question 10

implementation of entire biorisk management system

Answer 10

performance

Question 11

process of risk assessment

Answer 11

identify hazard/threat –> determine consequence
of an identified risk –> identify all existing controls and any additional ones that need to be applied.

Question 12

risk identification/threat identification

Answer 12

assessment

Question 13

likelihood or consequence evaluation

Answer 13

assessment

Question 14

elimination or substitution
engineering controls
administrative controls
practice and procedures
ppe

Answer 14

mitigation

Question 15

control, assurance, improvement

Answer 15

performance

Question 16

what is the hierarchy of controls from most effective to least effective

Answer 16

elimination, substitution, engineering controls, administrative vontrols, PPE

Question 17

Physically remove the hazard

Answer 17

elimination

Question 18

replace the hazard

Answer 18

substitution

Question 19

isolate people from the hazard

Answer 19

engineering controls

Question 20

change the way people work

Answer 20

administrative control

Question 21

protects woker with ppe

Answer 21

ppe

Question 22

shared comitment of management and employee to ensure safety of work environment

Answer 22

safety culture

Question 23

encourages every individual in an org. to project a level of awareness and accountability for safety

Answer 23

safety culture

Question 24

a _____ permeates all aspect of work environment

Answer 24

culture of safety

Question 24

a _____ permeates all aspect of work environment

Answer 24

culture of safety

Question 25

type of cabinets

Answer 25

fume hood, laminar flow cabinet (LFC), Biohazard safety cabinet (BSC)

Question 26

• Removes toxic chemical

Answer 26

FUME HOODS

Question 27

No HEPA filter -> not for
biohazard agents

Answer 27

fume hoods

Question 28

Product protection (no
personnel protection)

Answer 28

Laminar Flow Cabinets

Question 29

Not for biohazard
agents or chemical
fumes

Answer 29

laminar flow cabinet

Question 30

Class I BSC:

Answer 30

Personnel and Environment Protection

Question 31

Class II & III BSC:

Answer 31

Personnel, Product and Environment Protection

Question 32

BSCs provide —–
for work with —–material or ———
when they are properly maintained and used
in conjunction with good laboratory
technique

Answer 32

Biological safety cabinet

Question 33

Personnel protection is provided through a
continuous stream of inward air, known as

Answer 33

inflow

Question 34

helps prevent aerosol from escaping through front opening

Answer 34

inflow

Question 35

exhaust air is exhausted into

Answer 35

surrounding containment zone or directly to atmosphere

Question 36

air is —- to protect the environment

Answer 36

hepa-filtered

Question 37

HEPA stands for

Answer 37

High Efficiency Particulate Air

Question 38

ULPA stands for

Answer 38

ULPA: Ultra Low Penetration Air

Question 39

• HEPA: 99.99% - at ?? microns

Answer 39

0.3

Question 40

• ULPA: 99.999% - at —-??

Answer 40

0.12 microns

Question 41

The “classical” definition of
HEPA filter is 99.97% at 0.12
microns, but nowadays all BSC and
LF in US use 99.99% at 0.3 m.

T OR F

Answer 41

FALSE. The “classical” definition of
HEPA filter is 99.97% at 0.3
microns, but nowadays all BSC and
LF in US use 99.99% at 0.3 m

Question 42

Removes a broad range of airborne
contaminants:

Answer 42

HEPA/ULPA Capability

Question 43

impurity ion can affect

Answer 43

integrated circuit speed

Question 44

specialized clothing or equipment worn by an employee to provide protection against a hazard (e.g., infectious agents and toxins).

Answer 44

PPE

Question 45

completely isolates the employee from the laboratory environment.

Answer 45

Biosafety level 4 positive pressure suit

Question 46

The use of specific PPE required is determined through a

Answer 46

risk assessment

Question 47

determines the type of ppe required

Answer 47

characteristics of the infectious agent or toxin being manipulated and the type of laboratory procedures performed

Question 48

If there is a risk of creating an infectious biological aerosol (suspension of very fine particles or droplets in the air), use of

Answer 48

the proper respirator will prevent the worker from inhaling the infectious aerosol. This work can also be conducted in a biosafety cabinet to contain any aerosols created.

Question 49

Describes microscopic droplets that may contain infectious agents or toxins, similar to the droplets produced by a sneeze or a cough.

Answer 49

aerosol

Question 50

Some laboratory procedures including ——-, ——, ——–, ——————-and ———can produce aerosols.

Answer 50

Some laboratory procedures including sonication, centrifugation, vortexing, flow cytometry, fluorescence-activated cell sorting (FACS) and homogenization can produce aerosols.