Biopsychology Evaluations Flashcards

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1
Q

Localisation of Function: Evidence from Neurosurgery

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A strength of localisation theory is that damage to areas of the brain have been linked to mental disorders. Neurosurgery has been used for treating mental disorders by targeting specific areas of the brain.For example, Dougherty et al reported on 44 people with OCD who had undergone a cingulotomy. At post-surgical follow-up after 32 weeks, about 30% had met the criteria for successful response and 14% for partial response. The success of these procedures suggests that behaviours associated with serious mental disorders may be localised.

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2
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Localisation of Function: Evidence from Brain Scans

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A strength of localisation theory is evidence from brain scans which support the idea that many everyday brain functions are localised. For example, Petersen et al used brain scans to demonstrate how Wernicke’s area was active during a listening task and Broca’s area was active during a reading task. Also, Tulving et al revealed that semantic and episodic memories reside in different parts of the prefrontal cortex. These studies confirm localised areas for everyday behaviours and due to the objective methods used, provide sound scientific evidence that many brain functions are localised.

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3
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Localisation of Function: Contradictory Research Evidence

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A weakness of localisation theory is that not all research evidence supports its claims. For example, Lashley removed areas of the cortex (between 10% and 50%) in rats learning the route through a maze. No area was proven to be more important than any other area in terms of the rats’ ability to learn the route. The process of learning seemed to require every part of the cortex rather than being confined to a particular area. This suggests that higher cognitive processes, such as learning, are not localised but distributed in a more holistic way in the brain.

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4
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Localisation of Function:Language Localisation Questioned

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A weakness of localisation theory is that language may not be localised just to Broca’s and Wernicke’s areas. Dick and Tremblay found that only 2% of modern researchers think that language in the brain is completely controlled by these areas. Advances in brain imaging techniques mean that neural processes in the brain can be studied with more clarity. Language function seems to be distributed far more holistically in the brain than first thought. This suggests that, rather than confined to a couple of key areas, language may be organised more holistically in the brain, contradicting localisation theory.

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5
Q

Hemispheric Lateralisation and Split-Brain Research: Lateralisation in the Normal Brain

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A strength of lateralisation theory is research showing that even in normal brains the two hemispheres process information differently. For example, Fink et al used PET scans to identify which brain areas were active during a visual processing task in ‘normal’ participants.
When asked to attend to global elements of an image (such as looking at a picture of a whole forest) regions of the RH were much more active. When required to focus on the finer detail (such as individual trees) the specific areas of the LH tended to dominate. This suggests that, at least for visual processing, hemispheric lateralisation is a feature of a normal brain as well as the split-brain.

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6
Q

Hemispheric Lateralisation and Split-Brain Research: One Brain

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A limitation is that some aspects of lateralisation theory may be oversimplified. There may be different functions in the RH and LH, but research suggests people do not have a dominant side of their brain which creates a different personality. Nielsen et al analysed brain scans from over 1000 people and found that people used certain hemispheres for certain tasks, but there was no evidence of a dominant side, i.e. not artist’s/mathematician’s brain. This suggests that the pop-psychology notion of right- or left-brained people is incorrect.

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7
Q

Hemispheric Lateralisation and Split-Brain Research: Generalisation Issues

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A weakness of Sperry’s research is that causal relationships are difficult to establish. The behaviour of Sperry’s split-brain participants was compared to a neurotypical control group. An issue though is that none of the participants in the control group had epilepsy. This is a major confounding variable as any observed differences between the two groups may be a result of the epilepsy rather than the split brain. In addition to this, the sample size used by Sperry was very small. This is a weakness as these issues significantly affect both the internal and external validity of the findings.

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8
Q

Plasticity and Functional Recovery of the Brain: Age and Plasticity

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One strength of plasticity is that it does not always decline sharply with age. Plasticity reduces with age, but Bezzola et al demonstrated how 40 hours of golf training produced changes in the neural representations of movement in participants aged 40-60. Using fMRI, the researchers observed increased motor cortex activity in the novice golfers compared to a control group, suggesting more efficient neural representations after training. This demonstrates that neural plasticity can continue throughout the lifespan.

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9
Q

Plasticity and Functional Recovery of the Brain: Negative Plasticity

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A limitation of plasticity is that it may have negative behavioural consequences. Evidence has shown that the brain’s adaptation to prolonged drug use leads to poorer cognitive functioning in later life, as well as increased risk of dementia. Also, 60-80% of amputees have been known to develop phantom limb syndrome. These sensations are usually unpleasant, painful and likely due to cortical reorganisation in the somatosensory cortex. This suggests that the brain’s ability to adapt to damage is not always beneficial.

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10
Q

Plasticity and Functional Recovery of the Brain: Real-World Application

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A strength of functional recovery research is its real-world application. Understanding the process involved in plasticity has contributed to the field of neurorehabilitation. Simply understanding that axonal growth is possible encourages new therapies to be tried. For example, constraint-induced movement therapy is used with stroke patients whereby they repeatedly practise using the affected part of their body while the unaffected arm is restrained. This shows that research into functional recovery is useful as it helps medical professionals know when interventions need to be made.

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11
Q

Plasticity and Functional Recovery of the Brain: Cognitive Reserve

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A limitation of functional recovery is that level of education may influence recovery rates. Schneider et al revealed that the more time people with a brain injury had spent in education, the greater their changes of a disability-free recovery (DFR). 40% of those who achieved DFR had more than 16 years education compared to about 10% of those that had less than 12 years education. This would imply that people with brain damage who have insufficient cognitive reserve are less likely to achieve a full recovery.

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12
Q

Circadian Rhythms: Shift Work

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One strength of research into circadian rhythms is that it provides an understanding of adverse consequences that occur when disrupted. For example, night workers engaged in shift work experience a period of reduced concentration around 6am meaning mistakes and accidents are more likely. Research has also shown a relationship between shift work and poor health - shift workers are 3 times more likely to develop heart disease. This shows that research into the s/w cycle may have real-world economic implications in terms of how best to manage worker productivity.

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13
Q

Circadian Rhythms: Medical Treatment

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A strength of research into circadian rhythms is that it has been used to improve medical treatments. Circadian rhythms co-ordinate a number of the body’s basic processes, such as heart rate and hormone levels. These rise and fall throughout the day which has led to the field of chronotherapeutics. For example, aspirin as a treatment for heart attacks is most effective if taken last thing at night. Heart attacks are most likely to occur early in the morning, so the timing of taking aspirin matters. This shows that circadian rhythms can help increase the effectiveness of drug treatments.

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14
Q

Circadian Rhythms: Individual Differences

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A limitation of research into circadian rhythms is that generalisations are difficult to make. Many of the studies are based on small sample sizes, e.g. Siffre. S/w cycles may vary widely from person to person, e.g. Czeisler et al found evidence of s/w cycles varying from 13 to 65 hours. In addition, Duffy et al revealed that some people have a natural preference for going to bed early and rising early (‘larks’) whereas others prefer the opposite (‘owls’). This means that it is difficult to use the research data to draw conclusions, limiting the external validity.

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15
Q

Infradian and Ultradian Rhythms: Evolutionary Basis

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A strength of research into the menstrual cycle is that it may be explained by natural selection. Syncronisation of the menstrual cycle may have evolutionary value as it may have been advantageous for female ancestors to become pregnant at the same time. This would allow babies who had lost their mothers during childbirth to have access to breast milk, thereby improving their chances of survival. This is further supported by Penton-Voak et al who suggested that mate choice varies across the menstrual cycle. Women generally prefered feminised male faces (representing kindness) when picking a partner for a long-term relationship. However, during the ovulation phase women preferred more masculine faces (representing ‘good genes’ to be passed onto offspring). These findings indicate that sexual behaviour, influenced by infradian rhythms, is an adaptive strategy.

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16
Q

Infradian and Ultradian Rhythms: Methodological Limitations

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A limitation of synchronisation studies is their methodological shortcomings. There are many factors that may affect change in a woman’s menstrual cycle, including stress, diet, exercise etc. These may act as confounding variables, which means that any supposed pattern of synchronisation is no more than would have been expected to occur by chance. This may explain why other studies have failed to replicate the findings. This suggests that menstrual synchrony studies are flawed.

17
Q

Infradian and Ultradian Rhythms: Role of Melatonin

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A strength is that there is evidence to support the role of melatonin in SAD. Terman found that the rate of SAD is more common in northern countries, where the winter nights are longer, than southern countries. Research into the causes of SAD has led to practical applications through light therapy. Studies show this is effective in reducing the effects of SAD in about 80% of people (Sanassi). This provides a strength as by knowing possible causes of SAD, sufferers can be treated.

18
Q

Infradian and Ultradian Rhythms: Evidence for REM Sleep Stages

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There is evidence to support the idea of distinct stages of sleep. Dement and Kleitman monitored the sleep patterns of 9 adults in a sleep lab. Brain activity was recorded on an EEG and the researchers controlled EVs (caffeine, alcohol). REM activity during sleep was highly correlated with the experience of dreaming. Brain activity varied according to how vivid dreams were, and participants woken during dreaming could recall their dreams. Replications of this investigation have noted similar findings, providing reliable research that REM sleep is an important component of the ultradian sleep cycle.

19
Q

Infradian and Ultradian Rhythms: Individual Differences

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A limitation of research into ultradian rhythms is that there is significant variation between people. Tucker et al studied participants over 11 consecutive days and nights and found large differences between participants in terms of duration of each sleep stage, particularly stages 3 and 4. Tucker et al suggest that these differences are likely to be biologically determined. This makes it difficult to describe ‘normal sleep’ in any meaningful way and generalise findings to other people, limiting the external validity of this research.

20
Q

Endogenous Pacemakers and Exogenous Zeitgebers: Interactionist System

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A limitation of research is that endogenous pacemakers cannot be studied in isolation. Total isolation studies, e.g. Siffre’s cave study, are extremely rare. They also do not completely prevent entrainment from exogenous zeitgebers as Siffre used an artificial light which could have meant his biological clock was reset each time he turned the lamp on. In everyday life, pacemakers and zeitgebers interact, and it may make little sense to separate the two for the purpose of research. This suggests the more researchers attempt to isolate the influence of internal pacemakers, the lower the validity of the research.

21
Q

Endogenous Pacemakers and Exogenous Zeitgebers: Ethics

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A limitation of research into endogenous pacemakers is the use of animal studies. Although there are arguments that findings from animal studies can be generalised to humans as most mammalian brains have similar structure, there are critics that disagree with the use of animals in scientific research, primarily for ethical reasons. For example, in DeCoursey et al’s study the chipmunks were subject to an invasive procedure and exposed to risk when returned to their natural habitat, with most of them dying as a result. This is a weakness because what we can learn from these studies may not justify these unethical procedures.

22
Q

Endogenous Pacemakers and Exogenous Zeitgebers: Role of EZs may have been exaggerated

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Research conducted on the influence of EZs on biological rhythms suggests that their influence may be slightly exaggerated. Miles et al studied a young man, blind from birth, with a circadian rhythm of 24.9 hours. Despite exposure to social cues, his circadian rhythm could not be adjusted and consequently he had to take sedatives and stimulants to keep pace with the 24hr world. Similarly, studies of individuals who live in arctic regions have normal sleeping patterns despite the prolonged exposure to light in the summer months, when the sun does not set. Both of these examples suggest that there are occasions when exogenous zeitgebers may have little bearing on our internal rhythms.

23
Q

Ways of Studying the Brain: fMRI Strengths

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Non-invasive
Does not rely on radiation
High spatial resolution

24
Q

Ways of Studying the Brain: fMRI Weaknesses

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Very expensive
Poor temporal resolution - 5 second time-lag

25
Q

Ways of Studying the Brain: EEG Strengths

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High temporal resolution
Useful diagnostic tool

26
Q

Ways of Studying the Brain: EEG Weaknesses

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Poor spatial resolution
Generalised information

27
Q

Ways of Studying the Brain: ERP Strengths

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More specificity than EEG
High temporal resolution
Useful for measuring cognitive functions

28
Q

Ways of Studying the Brain: ERP Weaknesses

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Lack of standardisation in methodology between studies
Background ‘noise’ must be completely eliminated

29
Q

Ways of Studying the Brain: Post-Mortems Strengths

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More detailed examination
Foundation for early understanding of processes

30
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Ways of Studying the Brain: Post-Mortems Weaknesses

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Affected by extraneous variables
Retrospective data
Ethical issues - consent