Biopsychology Flashcards

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1
Q

Robert suffered a stroke at the age of 55. After the stroke he was paralysed down his right side, though he could move his left arm and leg easily. Robert could clearly understand what was said to him, but was unable to produce any speech.

Discuss how knowledge of hemispheric lateralisation and language centres in the brain has helped our understanding of cases such as Robert’s.
Refer to Robert’s case in your answer

A
  • different parts of the brain perform different functions

- functions are specific to individual parts of the parts

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2
Q

what two halves is the brain divided into

A

the left and right hemisphere which are divided by a small gap

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3
Q

what is localised to the left hemisphere

A

language

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4
Q

what is localised to the right hemisphere

A

spatial skills

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5
Q

what is hemispheric lateralisation

A

different sides of the brain perform different functions

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6
Q

Patient tan lost the ability to speak. Based on your knowledge of hemispheric lateralisation, where did Tan have damage

A

left hemisphere

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7
Q

what is Contralateral organisation

A

is when the right hemisphere controls the left side of the body, and the left hemisphere controls the right side of the body.

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8
Q

what are both hemispheres of the brain involved in

A

the 5 senses and controlling our movement

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9
Q

what does contralateral mean

A

opposite side

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10
Q

what functions are organised contralaterally

A

vision, movement, touch

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11
Q

how do the right and left hemisphere communicate

A

communicate by sending nerve impulses to each other using the corpus callosum.

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12
Q

what is the The corpus callosum

A

a bundle of axons that connect the hemispheres. It acts as a bridge between the two hemispheres

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13
Q

what does it mean if some functions are processes by only one side of the brain

A

they are hemispherically lateralised

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14
Q

Explain what is meant by contralateral brain organisation

A

Contra means ‘opposite’, and lateral means ‘side’, so contralateral means that some functions of the brain controls the opposite side of the body. Contralateral brain organisation means that the right hemisphere controls the left side of the body, and the left hemisphere controls the right side of the body.

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15
Q

Which two regions of the brain are involved in the fight or flight response?

A

Hypothalamus, pituitary gland.

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16
Q

what are split brain patients

A

patients whose corpus callosum has been cut

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17
Q

what happens when he corpus callosum is cut

A

the two hemispheres can no longer communicate

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18
Q

what is the procedure used in split brain research study

A
  • patients are sometimes asked to respond to a stimulus that has been presented to them, by pointing at the stimulus that matches the one they were shown
  • patients are sometimes asked to describe a stimulus that has been presented to them
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19
Q

what is the method used in split brain research

A

1) present stimulus to left or right side of brain

2) ask patient to respond to the stimulus

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20
Q

what are the results of split brain research

A

Sperry’s study:
he concluded that language is hemispherically lateralised to the left hemisphere
patients could match the pictures whether or not it was presented to the right or left hemisphere

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21
Q

In Sperry’s original study, he showed split-brain patients a stimulus, to either their right or left hemisphere. He then later asked patients to point to that same stimulus, when showed a choice of four different ones. Patients could point to the correct image. Explain why this happened.

A

The ability to visually process and identify the image isn’t hemispherically lateralised. Therefore regardless of which hemisphere the information was presented, the participant had still processed the information and was able to point to the correct stimulus from the choice of four.

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22
Q

When participants were asked to respond verbally to a stimulus, their response depended on which side the information was presented to. Explain why these results occurred in Sperry’s subsequent study.

A

The ability to say what was processed by the left hemisphere occured because language is hemispherically lateralised to the left hemisphere. If a stimulus is presented to the right hemisphere, a split brain patient is unable to identify or describe it, because language is not processed in the right hemisphere.

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23
Q

What are the limitations of split-brain research?

A
  • the study contains confounding variables
  • the study has not been consistently replicated
  • the study lacks generalisability
  • the participants brains were abnormal
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24
Q

what could Danelli conclude about hemispheric lateralisation from doing a case study on EB

A

hemispherically lateralised functions can be taken over by the other hemisphere in some conditions

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25
Q

Explain one issue of using patients who have undergone split-brain surgery to study hemispheric lateralisation of normal people’s brains.

A

Split-brain patients have had the surgery to split their brain because they were experiencing severe seizures. So, it’s possible that these patients’ brains are organised differently to other people’s brains. Therefore this is a confounding variable in the interpretation of the study, because it may actually be their different brains that cause any results rather than their corpus callosum being severed.

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26
Q

what is the cortex

A

the outer surface of the brain

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27
Q

what does the motor cortex do

A

controls body movement on the right side of the body

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28
Q

what does the somatosensory cortex do

A

processes the feeling of touch. the somatosensory cortex in the right hemisphere controls the left side of the body. and the somatosensory cortex in the left hemisphere controls the right side of the body

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29
Q

where is the somatosensory cortex located

A

behind the motor cortex

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30
Q

how does the auditory cortex process sounds

A

by receiving nerve impulses or impulses from sensory neurones that talk to sensory receptors in the ears

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31
Q

where is the auditory cortex located

A

behind and slightly below the somatosensory cortex

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32
Q

what does the auditory cortex do

A

processes sound. There is an auditory cortex in both hemispheres, but the auditory cortex is not organised contralaterally

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33
Q

where is the visual cortex located

A

right at the back of the brain

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34
Q

what des the visual cortex do

A

processes vison. Both hemispheres are involved in processing vison. The visual cortex works by receiving nerve impulses from sensory neurones that talk to sensory receptors in your eyes. Vison is organised contralaterally

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35
Q

where is the brocas area located

A

below and slightly in front the motor cortex

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36
Q

what is the function of brocas area

A

involved in producing language, so we can say it is hemispherical lateralised to the left hemisphere

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37
Q

where is the Wernickes area located

A

behind the auditory cortex

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38
Q

what is the function of wernickes area

A
  • enables us to understand written language
  • enables us to understand speech
  • hemispherically lateralised to the left hemisphere
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39
Q

what is aphasia

A
  • when people lose the ability to produce language

- when people lose the ability to understand language

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40
Q

what is brocas aphasia

A

inability to produce language

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41
Q

what is Wernickes aphasia

A

inability to understand language

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42
Q

Bella was in a terrible car crash and received severe damage throughout the whole cortex of her right hemisphere.
What symptoms would we expect Bella to exhibit?

A
  • Loss of vision to the left of her body.
  • Loss of movement to the left half of her body
  • Loss of sensation of touch to the left half of her body.
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43
Q

In a conversation, Joseph listens and can understand what people are saying. However, he struggles to express himself verbally. His dad suggested that he writes down what he thinks, or acts it out, but he struggles with this too - his left hand and arm feel like they’re not doing what he wants them to do.
Using the information above, explain what areas of Joseph’s brain might be damaged and why.

A

Joseph’s Broca’s area could be damaged because he is struggling to create language - he can’t find the right words to express himself. His right motor cortex may also be damaged, because he is struggling to use his left arm and hand, and his right motor cortex controls the left side of his body. Joseph isn’t having any problems with touch sensations, right side of his body or understanding language, so his somatosensory cortex, left motor cortex and Wernicke’s areas seem to be ok.

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44
Q

what are the limitations of localisation of function

A
  • may be over simplified because a complex function often requires more than one brain region/ area
  • ignores the importance of communication between brain regions
  • it ignores individual differences in brain organisation
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45
Q

what are the criticism of patients tan research

A

Dronkers found that patient tan had damaged other regions of his brain outside of Brocas area. Dronkers supports the idea that more than one region is responsible for language production

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46
Q

Explain why case studies of patients like Tan support the idea of brain localisation.

A

Tan displayed difficulties with producing language, and after he had died a post-mortem examination showed damage to his Broca’s area. This suggests that damage to that particular area had caused Tan’s symptoms, supporting that different areas have specific functions.

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47
Q

Explain what Dejerne’s study tells us about brain localisation.

A

The study demonstrates that the idea that only one brain region contributes to a function is over-simplified. It also shows that even the idea of multiple brain regions contributing to a function is over-simplified. The study illustrates the importance of communication between brain regions, rather than just looking at one area as important to a function.

48
Q

what parts of the brain are important for memory

A

temporal lobe, frontal cortex and hippocampus

49
Q

what regions are located on the brains surface

A
  • somatosensory cortex ‘
  • visual cortex
  • wernickes area
50
Q

what regions are located in the middle of the brain

A
  • hypothalamus
  • pituitary gland
  • hippocampus
  • cerebellum
51
Q

what is a functional recovery

A
  • when a function is regained after brain damage

- when a function is transferred from a damaged brain region to an undamaged brain region

52
Q

what is synapse strengthening

A

first step of functional recovery

when the likelihood of of nerve impulses being transmitted during synaptic transmission increases

53
Q

what is the role of synapse strengthening in functional recovery

A

after brain damage, synapse strengthening occurs, meaning that synapse is strengthened in brain regions near the damaged area

54
Q

what is neural rewiring

A

second step for functional recovery
axons from brain regions that used to communicate with the damaged regions rewire to to form connections with nearby brain regions

55
Q

does the case of Gage support the localisation of function theory or the holistic theory

A

the case of Gage supports the localisation of functions theory. it supports the idea that certain functions are associated with specific areas of the brain. in Gages case it was evident that the frontal lobe is associated with personality as Phineas changed

56
Q

what does plasticity mean

A

refers to how flexible something is eg muscles in our body

57
Q

what does brain plasticity mean

A

refers to the brains ability to change and adapt because of experience. Research has demonstrated that the brain continues to create neural pathways and alter existing ones in response to changing experiences

58
Q

what is functional recovery

A

a form of plasticity, the brains ability to redistribute or transfer functions: following damage through trauma

59
Q

what does pruning mean

A

where connections are lost due to lack of use

60
Q

what does Bridging mean

A

where new connections are created due to use and new stimulus

61
Q

what was Kuhn study about functional recovery and brain plasticity

A

got participants to play Mario games for 30 mins per day for two months and then compared their brain development to a control who didn’t. Found significant difference in grey matter of video game participants particularly in cortex

62
Q

how does the plasticity of our brain change with age

A

with age gets rid of connections that we no longer use (synaptic pruning ) + adapts to create new connections for new learning

63
Q

what did Maguire find in a study of taxi drivers ? How does this support plasticity

A

found significant amounts of grey matter in the post terior hippocampus than in the control group. This part of the brain is associated with spatial skills and navigational skills. This supports plasticity as it shows that the brain can permanently change in response to frequent exposure to a particular task

64
Q

what did Draganski et al (2006) find about plasticity

A

imaged the brains of medical students three months before and after their final exams. Learning induced changes were seen to have occurred in the posterior hippocampus and the parietal cortex presumably as a result of the exam

65
Q

what exactly happens during functional recovery after trauma? how does the brain quickly adapt

A

After trauma, such as stroke, unaffected areas of the brain are often able to adapt + compensate for those areas that are damaged. Neuroscientists suggest it is a spontaneous recovery then slows down after weeks/ months

66
Q

what is synaptic pruning

A

as we age, rarely used connections are deleted and frequently used connections are strengthen end

67
Q

what is axonal sprouting

A

undamaged axons grow new nerved endings to reconnect neurons whose links were injured or severed

68
Q

what is the A03 for plasticity

A

+ evidence in animal studies
+ continues through age
+ practical application of neural rehabilitation
- potential negative consequences

69
Q

what is the evidence of brain plasticity in animal studies

A

nubel and wise (1963) sewed one eye on a kitten shut and analysed the brains cortical response. this shows how loss of function leads to compensatory activity in the brain

70
Q

what are the potential negatives consequences of brains plasticity

A

Ramachandran & hirstein found that 60-80% of amputees have developed phantom limb syndrome

71
Q

what type of experiment was sperrys spilt brain experiment

A

a quasi experiment 11 participants who were epileptic and had their corpus callosum cut

72
Q

what are FMRIs scans

A

A brain scanner which measures increased blood flow to brain sites when individuals are asked to perform cognitive/physical tasks. Increased blood flow indicates increased demand for oxygen in that area.

73
Q

what are the strengths of FMRIs

A

Non-invasive – No insertion of instruments unlike PET and no exposure to radiation – Beneficial to the economy as there is no recovery time so people don’t have to be off work.

74
Q

what are the limitations of FMRIs

A

Expensive –
fMRI only measures blood flow – it cannot home in on the activity of individual neurons therefore it’s hard to tell exactly what brain activity is being represented on the screen – High likelihood that the findings will be misinterpreted as it doesn’t show activity like EEG/ERP.

75
Q

what are EEGs

A

Measures electrical activity in the brain using electrodes attached to the scalp, and measures how electrical activity in the brain varies over time/in different states (e.g. waking vs. asleep). EEG readings can detect epilepsy and Alzheimer’s.

76
Q

what are the strengths of EEGS

A
  • EEGs have medical applications in diagnosing disorders such as epilepsy and Alzheimer’s.
  • Non-invasive - No insertion of instruments EEGs are virtually risk free and is avoidant of any danger to the brain itself.
  • Cheaper than fMRI thus making them more available – Psychologists can gather more data on the functioning of the human brain thus contributing to our understanding of different psychological phenomena.
77
Q

what are the limitations of EEGS

A

Not highly accurate – electrical activity detected in several regions of the brains simultaneously – Very hard to pinpoint exactly which area is producing this activity. therefore cannot distinguish differences in activity between 2 closely adjacent areas.
• Uncomfortable – Hard for the patients as electrodes are attached to their head – Could result in an unrepresentative reading as the patients discomfort could trigger cognitive responses to the real time situation.

78
Q

what are ERPs

A

ERP’s are very small voltage changes in the brain triggered by specific events or stimuli which are measured using an EEG.
Measures small voltages of electrical activity when a stimulus is presented.

79
Q

what are the strengths of ERPs

A

Non-invasive - No insertion of instruments no exposure to radiation – Virtually risk free and is avoidant of any danger to the brain itself.

80
Q

what are the limitations of ERPs

A
  • only monitors electrical activity in outer layers of the brain, therefore, cannot reveal electrical activity deep down in the brain
  • poor spatial resolution
81
Q

what are circadian rhythms

A

biological rhythms that occur over a 24 hour cycle

82
Q

what are biological rhythms

A

patterns of changes in body activity over cyclical periods

83
Q

what are ultradian rhythms

A

biological rhythms occur more than one in 24 hours

84
Q

what are intradian rhythms

A

biological rhythms that occur less than one cycle in 24 hours

85
Q

what are endogenous pacemakers

A

internal body clocks that regulate biological rhythms

86
Q

what are exogeneous Zeitgebers

A

External cues that influence our biological rhythms

87
Q

what does the brains circadian clock regulate

A
  • sleeping + feeding patterns
  • alertness
  • core body temp
  • urine production
88
Q

what is affected by the circadian clock

A
melatonin= produced in pineal gland in brain, chemically causes drowsiness and lowers body temp
cortisol = produced in the adrenal gland, and used to form glucose + enables anti stress
89
Q

where is the circadian clock located

A

in the SCN in the hypothalamus of the brain one in each brain hemisphere

90
Q

note when sleep wake cycles occur

A

core temp = 4:30-5:00 am
melatonin produced 8-9pm and stops at 7-8 am
sleepiness occurs 2-3am

91
Q

what did Aschoff and weber (1976) find about circadian rhythms

A

found that participants placed in WW2 bunker underground with the absence of any environmental and social cues displayed circadian rhythms between 24-25 hours, with some as long as 29 hours
This shows that circadian rhythms operate in the absence of external cues

92
Q

what did folkard (1985) find about circadian rhythms

A

isolated 12 participants from natural light for 3 weeks ( dark cave ) manipulating clocks so that only 22 hours passed a day
one of the Ps could adjust to the clock, showing the strength of circadian rhythms

93
Q

what endogenous pacemakers and exogeneous Zeitgebers are likely to influence your sleep wake cycle? how?

A

pacemaker= SCN, the lack of light stimulates the SCN, which sends signals to the pineal gland to release melatonin, which in turn promotes wakefullness os sleep is triggered
light + Zeitgebers as demonstrated by campell + murphey who found that circadian rhythms were shifted when light was shone at the back of knees

94
Q

AO3 for circadian rhythms

A
  • support from cave study
  • issues with cave study evidence
  • poor control of studies
95
Q

what is a silent synapse

A

a synapse that becomes inactive due to lack of nerve impulses

96
Q

what is the 3rd mechanism to enable functional recovery

A

unmasking neural connections

97
Q

what are mechanisms for brain plastcity

A
  • rewiring
  • synapse strenthening
  • neural unmasking
98
Q

Explain how neuronal unmasking contributes to learning

A

Neuronal unmasking is when silent synapses become active and so reveal hidden neuronal connections between brain regions. These hidden connections reactivate to help our brain to change and adapt to new experiences, which contributes to learning.

99
Q

what is the method for maguire taxi study

A
  • used a MRI scanner to investigate brain plasticity
  • performed quasi experiment
  • compared the brain of london taxi drivers to non taxi drivers
100
Q

what are the limitations of maguire taxi study

A
  • didn’t use random allocation because she couldn’t directly manipulate the IV
  • couldn’t establish a cause and effect relationship, because she couldn’t directly manipulate the IV
  • couldnt control the participant variable, because it was a quasi experiment
101
Q

what are infradian rhythms

A

last longer than 24 hours and can be weekly, monthly and annually such as menstrual cycle and hibernation in animals

102
Q

what happen occurs in the monthly infradian rhythm of menstrual cycles

A
  • regulates hormones
  • ovulation occurs half way through cycle when oestrogen cycles are highest
  • after ovulation, progesterone levels increase, ready for possible embryo
103
Q

what is sad

A
  • seasonal affective disorder is an infradian rhythm, related to the seasons (yearly cycle)
  • melatonin is secreted by the pineal gland at night
  • longer nights= increased melatonin secretion
  • linked to increase in depressive symptoms
104
Q

what did Reinberg say about infradian rhythms

A

A03 examined a woman who spent three months in cave with only a small lamp to provide light. Reinberg noted that her menstrual cycle shortened from the usual 28 days to 25.7 days. This suggests that exogeneous Zeitgebers such as light helps regulate our menstrual cycle

105
Q

what did Russel et find about infradian rhythms

A

A03 found that female menstrual cycle became synchronised with other females through odour exposure. In one study, sweat samples from one group of women were rubbed onto the upper lip of another group. Despite the fact that the two groups were separate their menstrual cycle was synchronised

106
Q

what does Russel et al study suggest

A

this suggest that synchronisation of menstrual cycle can be affected by pheromes (exogenous Zeitgebers) which have an affect on people nearby rather than the person producing them

107
Q

what are ultradian rhythms

A

fewer than 24 hours such as meal patterns and human sleep patterns
this also means that you can go through more than one cycle

108
Q

what happens in stage 1 and 2 of human sleep patterns

A
  • light sleep- brain patterns become slower ( starting with alpha waves, progression to theta waves
109
Q

what happens in stage 3 and 4 of human sleep patterns

A
  • deep sleep or slow wave sleep stage ( associated with delta waves)
110
Q

what happens in stage 5 of human sleep patterns

A
  • REM = rapid eye movement.

- body is paralysed: desynchronised brain waves

111
Q

what is the randy Gardener study on ultradian rhythms

A

he remained awake for 264 hours
- after this experience, Randy slept for just 15 hours and over several nights has recovered only 25% of his lost sleep. Interestingly, he recovered 70% of stage 4 sleep and very little of other stages

112
Q

what does the study on randy gardener show

A

the results highlight the large degree of flexibility in terms of the different stages within the sleep cycle and the variable nature of this ultradian rhythm

113
Q

what did Tucker et al find about ultradian rhythms

A

AO3 found significant differences between participants in terms of the duration of each stage, particularly stage 3 and 4 ( just before REM)

114
Q

what dies Tucker et al study demonstrate

A

demonstrates that there may be innate differences in ultradian rhythms which means that it is worth focusing on these differences during investigations into sleep cycles

115
Q

what was the method used in Maguire’s study?

A
  • quasi experiment
  • IV = participants job, natural occurrence
  • DV= volume of hippocampus
116
Q

what are the limitations for Maguire study

A

quasi = couldn’t control participant variables, also couldn’t randomly allocate participants to either experimental or control group