Biopsychology Flashcards

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1
Q

What is the difference between the localisation of function theory and the holistic theory (of the brain)?

A

Localisation of function: idea that different areas of brain are responsible for different behaviours, processes or activities

Holistic theory: ALL parts of brain were involved in processing of thought and action.

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2
Q

Define brain lateralisation and outline the general rule about lateralisation in the 2 hemispheres?

A

The idea that the 2 hemispheres are functionally different and that each have functional specialisations
- activity on left-side of body are controlled by right hemisphere and vice versa

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3
Q

What is the cerebral cortex?

A

The outer layer of both hemispheres, which is about 3mm thick and is what separates is from animals as the human cortex is much more developed

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4
Q

Name the four lobes found on the cortex.

A

F-POT (drawn clockwise)

  1. Frontal lobe
  2. Parietal lobe
  3. Occipital lobe
  4. Temporal lobe
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5
Q

Which area is found on the back of the frontal lobe?

A

MOTOR AREA : Controls voluntary movement in opposite side of body
- damage here may lead to loss of control over fine movements

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6
Q

Which area is found on the front of parietal lobes?

A

SOMATOSENSORY AREA: processes sensory info such as touch or heat.

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7
Q

Which area is found in the occipital lobe (at the back of the brain) ?

(GIVE EXAMPLE)

A

VISUAL AREA: Receives and processes visual info from opposite visual fields, e.g left visual cortex processes info from right visual field and vice versa

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8
Q

Which area is found on the temporal lobes?

A

AUDITORY AREA: analyses speech-based info

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9
Q

Define broad aphasia?

A

A condition that is caused by damage to the brocas area (area responsible for speech production).
- sufferers speech tends to be slow and lacking in fluency

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10
Q

Define wernickes aphasia

A

A condition caused by damage to the Wenicke’s area (area in left hemisphere responsible for language comprehension)
- sufferers tend to have fluent speech but speech often lacks in meaning/is nonsense

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11
Q

Evaluate the ‘localisation of function’ theory.

A

Strengths

  1. Brain scan evidence: tulving et al found that semantic and episodic memory is found in diffefent parts of the pre-frontal cortex.
  2. Neurosurgical evidence: dougherty et al found that OCD patients got better after having a cingulatomy (lesioning of **cingulate cyrus)

Weaknesses
4. Lashley research: Lashley found that rats used every part of their cortex to learn a maze. This suggests that learning is distributed in a more holistic way in brain

  1. Plasticity: research found that when a function is lost, brain reorganises itself to recover lost function. (e.g there are cases about stroke victims being able to recover lost abilities.
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12
Q

Define plasticity

A

Plasticity = the brains tendency to change and adapt (functionally and physically) as a result of experience and new learning

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13
Q

Describe the findings of one research into plasticity

A

Maguire et al: found that London taxi drivers showed significantly more volume of grey matter in posterior hippocampus (associated with spatial and navigational skills) than control group.
- the longer the driver had been in the job, the more pronounced was the structural difference

(both are results of learning and experience)

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14
Q

Define functional recovery

A

Following damage through trauma, the brains ability to redistribute or transfer functions usually performed by a damaged area to other, undamaged areas

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15
Q

What happens in the brain during recovery?

(HINTS:

  • new synaptic connections
  • secondary neural networks
  • axonal sprouting
  • reformation of blood vessels
  • recruitment of homologous areas
A
  1. Brain wires and reorganise itself by forming new synaptic connections close to damaged area.g
  2. Secondary neural pathways: these would be activated to allow functioning to continue. This process is supported by:
    - Axonal sprouting: growth of new nerve endings which connect with other undamaged nerve cells to form new neuronal pathways
    - Reformation of blood vessels: to allow flow of oxygenated blood and nutrients to cells
    - Recruitment of homologous (similar) areas on opposite side of brain to perform specific tasks: e.g. If brocas area was damaged on left side of brain, right equivalent would take over role. After a period of time, functionality may shift back to left.
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16
Q

Evaluate the theory of brain plasticity

A

Strengths

  1. Maguire et al research
  2. Practical application (contributed to neurorehabilitation) : understanding that plasticity/spontaneous recovery slows down after some weeks has prompted us to use own techniques to maintain improvements in functioning e.g. Movement therapy.
  3. Gabby Giffords/phineas gage
  4. Hubel and Weisser: sewed one eye of a cat but still found that visual cortex activity associated with that eye continued to process info from open eye.
  5. Plasticity maintained with age: research found reduced motor cortex activity in 40-60 yr old golfers when compared with control group. This suggests neural plasticity can continue throughout lifespan)

Limitations

  1. ** Negative plasticity: theory doesn’t include maladaptive behavioural consequences of brains ability to rewire itself (e.g. Prolonged drug use can result in poorer cognitive functioning as well as dementia)
  2. Age and plasticity: functional plasticity can reduce with age as brain has greater propensity for reorganisation in childhood as it is constantly adapting to new experiences and learning).
  3. HUBER AND WEISSER - HIGHLY UNETHICAL
  4. Phineas Gage results may be due to researchers own subjective experience
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17
Q

Name 4 ways of investigating the brain

A
  1. Functional motor resonance imaging (fMRI)
  2. Electroencephalogram (EEG)
  3. Event-related potentials (ERPs)
  4. Post-mortem examinations
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18
Q

How do fMRIs work?

A

Parts of the brain that are more active require more 02, so blood flow is directed to these areas (Haemodynamic response).
- MRI technology allows researchers to detect changes in blood flow/ detect the areas that are high in O2, and thus, detect the areas that are active.

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19
Q

Evaluate the use of fMRIs.

A

Strengths

  1. Safer as it doesn’t use radiation
  2. Produced images in very high spatial resolution (great detail)

Weaknesses

  1. Expensive
  2. Only produces clear image if person stays very still
  3. Poor temporal resolution (there is a 5 second lag between the image on screen and the initial firing of neuronal activity.
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20
Q

How do EEGs work?

A

They record tiny electrical impulses produced by the brains activity.
- By measuring characteristic wave patterns, the EEG can help diagnose certain conditions of the brain

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21
Q

Evaluate the use of EEGs.

A

Strengths

  1. Has helped with diagnosis of epilepsy
  2. Contributed to our understanding of stages involved in sleep (ultradian rhythms)
  3. High temporal resolution (can detect at a millisecond)

Weaknesses

  1. Cannot pinpoint exact source of neural activity
  2. Doesn’t allow researchers to distinguish between activities originating in different but adjacent areas.
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22
Q

How do ERPs work?

A

They show the brain’s electrophysiological response to a specific sensory, cognitive, or motor events, which can be isolated through statistical analysis of EEG data.
- They help researchers view performance of a specific task or the presentation of a specific stimulus.

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23
Q

Evaluate the use of ERPs.

A

Strengths

  1. High temporal resolution
  2. supports localisation as its more specific in terms of measuring neural processes ( it can isolate motor, cognitive or sensory events/responses). e.g. has allowed us to find out the brain’s P300 component is involved in allocating attentional resources and maintaining working memory.

Weaknesses
3, lack of standardisation: In order to obtain pure data, background noise and extraneous material must be eliminated but this is not always possible.

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24
Q

How do post-mortem examinations work?

A

Brains are analysed after death to determine whether certain observed behaviours during the patients lifetime can be linked to abnormalities of the brain.
- may involve comparison with a ‘neurotypical’ brain in order to observe differences.

25
Q

Evaluate the use of post-mortem examinations?

A

Strengths
1. Provided foundation for understanding key processes as Broca and Wernicke both relied on these to establish links between language, brain and behaviour, decades before neuroimaging was invented.

Weaknesses

  1. Causation: deficits in brain may be linked to other unrelated traumas
  2. Ethical issues: Patients such as HM, did not provide informed consent but tests were conducted nevertheless.
26
Q

What was the main aim behind split-brain research?

A

Researchers wanted to investigate extent to which brain function is lateralised by studying epileptic patients who had corpus callosum and other similar tissue that connected 2 hemispheres cut (commissurotomy)

27
Q

Describe the procedure of one split-brain study

A

SPERRY

  1. An image or word is projected to patients RVF (processed by LH) and another image to LVF ( processed by RH)
    - In a normal brain, corpus callosum ‘shares’ info between both hemispheres. In split brain, the info can’t be conveyed from chosen hemisphere to other.
28
Q

What categories did Sperry use to measure brain lateralisation? Describe Sperry’s results?

A
  1. Describing what was seen
  2. Recognition by touch
  3. Composite words
  4. Matching faces.
29
Q

Describe Sperry’s results for:

  1. Describing what was seen
  2. Recognition by touch
A
  1. Describing what was seen: When object shown to RVF, patients could easily describe what was seen but couldn’t when shown to LVF. This is because RH lacks language centres, and message from LH couldn’t be shared to RH.
  2. Recognition by touch: patient couldn’t verbally identify object but could ‘understand’ what the object was and select the corresponding object (using RH)
30
Q

Describe Sperry’s results for:

  1. Composite words
  2. Matching faces
A
  1. Composite words and matching faces: When 2 words were presented on either side of visual field (e.g. key and ring) patient selects key with left hand, and says the word ring (as they lack language on RH to correctly indentify object as a key.

.4. Matching faces: pic made up of 2 different halves of a face was presented (one half to each hemisphere). Results found that LH dominated verbal description of faces whilst RH dominated selection of matching

31
Q

Evaluate split-brain research

A

Strengths

  1. Research has shwon lateralised brain functions: Research such as Sperry’s has shown that LH is responsible for language skills, whilst RH is adept at spatial tasks and the arts.
  2. Standardised procedure: image was flashed 0.1 seconds for each ppt, which gave them no time to move eyes over image and spread info across both visual fields/both sides of the brain. This allowed Sperry to ensure only 1 hemisphere received info at a time.

Limitations

  1. Generalisability: Only 11 patients took part, all with a history of seizures. Split-brains may give different results to normal brains.
  2. overstated conclusions: Some researchers suggest that many behaviours that are typically associated with 1 hemisphere can be performed by the other when required. They say that Sperry’s conclusions were too simplistic.
32
Q

Define biological rhythms?

A

Biological rhythms are periodic activity, governed by

  1. Internal biological ‘clocks’ (endogenous pacemakers)
  2. External changes in the environment (exogenous zeitgebers)
33
Q

What are circadian rhythms?

A

A type of biological rhythm, subject to a 24 hour cycle, which regulates a number of body processes such as the sleep/wake cycle and changes in core body temp.

34
Q

What changes may affect the sleep/wake cycle?

A
  1. Exogenous zeitgebers = light

2. Endogenous pacemakers = free-running biological clock ‘left to its own devices’ without the influence of light.

35
Q

Name 2 studies that supports circadian rhythms?

A
  1. Michael Siffre (1962)

2. Aschoff and Wever

36
Q

Describe the procedure and findings of Siffre’s study

A

Procedure: Spent long periods in dark caves to examine effects of endogenous pacemakers.

Results: In each case study, Siffre;s free running circadian rhythm settled down to just above 24 hours.
- Importantly, he had a regular sleep/wake cycle

37
Q

Describe the procedure and findings of Aschoff and Wever’s study.

A

Procedure: Group of pps spent 4 weeks in a WW2 bunker deprived of natural light.

Results: All but one showed a circadian rhythm between 24 and 25 hours

38
Q

What conclusions did Siffre and Aschoff and Wever draw from their experiments?

A

They concluded that the natural sleep/wake cycle may be slightly longer than 24 hours but is entrained by exogenous zeitgebers associated with our 24-hour day (e.g. number of daylight hours, typical mealtimes etc.)

39
Q

Which one - exogenous zeitgebers or endogenous pacemakers - may have stronger influence?

A

Endogenous pacemakers

40
Q

Describe the procedure/findings/conclusion of a study that supports endogenous pacemakers having a stronger influence?

A

Folkard et al

Procedure: Studied 12 ppl in dark cave for 3 weeks, going to bed when clock said 11:45pm and waking when it said 7:45am
- researchers gradually speeded up clock (without pps knowing) so an apparent 24-hr cycle eventually lasted 22 hours.

Results: Only 1 ppt adjusted to new regime

Conclusion: Biological clocks have stronger influence than external changes in environment.

41
Q

Evaluate research into circadian rhythms

A

Strengths

  1. Practical application to shift work: Research found that shift workers experience lapse of concentration at around 6am due to work times effect on sleep/wake cycle. Businesses can work on how best to manage worker productivity to strengthen economy
  2. Practical application to drug treatment: Circadian rhythm research shows there are times during day/night when drugs are more effective as circadian rhythm co-ordinate body’s basic processes (e.g. hormone levels)

Limitations

  1. Generalisability: Aschoff and Wever/Folkard used small sample of ppts so results may not be representative of entire pop.
  2. Poor control: Czeisler suggests that even artificial light may have an effect on sleep/wake cycles and Siffre had a lamp turned on during the day.
  3. Individual differences: Some people are morning people/night owls/teenagers who need more sleep. Czeisler showed the effect of individual differences when he found that sleep/wake cycles could range from 13 to 65 hours.
42
Q

What are infradian rhythms?

A

Biological rhythms that take more than a day to complete (e.g the Menstrual cycle and SAD)

43
Q

What happens during the menstrual cycle?

A
  1. Rising levels of oestrogen causes ovary to develop and release an egg (ovulation)
  2. Then progesterone helps womb lining thicken, readying body for pregnancy.
  3. If pregnancy doesn’t occur, womb lining breaks down and leaves the body
44
Q

What changes can synchronise menstrual cycles and outline the procedure/findings of a study that support this?

A

Exogenous Zeitgebers

STERN AND McClintock (1998)

Procedure: studied 29 women with irregular periods. Pheromones were taken from some at different stages of their cycles. These pads were cleaned with alcohol and rubbed on the upper lips of other ppts

Results: 68% of women experiences changes to their cycle, which brought them closer to cycle of their ‘odour donor’.

45
Q

What are circannual cycles?

A

A type of infradian rhythm that occur yearly

46
Q

Define SAD

A

SAD (seasonal affective disorder) is a depressive disorder linked to seasonal patterns

  • it is often called ‘winter blues’ as the symptoms are triggered during winter months, when the hours are shorter.
  • it is a circannual rhythm
47
Q

What is suggested to be the cause of SAD?

A
  1. During the night, the pineal gland secretes melatonin until dawn, when there is an increase in light.
  2. During winter, lack of light in the morning means secretion goes on for longer
  3. This has a knock-on effect on the production of serotonin in the brain (low serotonin is linked to depressive symptoms)
48
Q

What are ultradian rhythms?

A

Rhythms that occur many times a day (e.g. Stages of sleep)

49
Q

How many stages of sleep are sleep are there?

A

5 stages, categorised by a different level of brainwave activity (monitored by EEG)

50
Q

Outline the different stages of sleep?

A

Stages 1 and 2: light sleep. Brainwaves become slower and more rhythmic (alpha waves), slowing further as sleep becomes deeper (beta waves)

Stages 2 and 3: difficult to rouse someone. Deep sleep characterised by delta waves which are slower/have a greater amplitude.

Stage 5: REM sleep. Fast, jerky activity of eyes. Body paralysed yet brain activity speeds up

51
Q

Evaluate research into infradian and ultradian rhythms

A

Strengths

  1. Stength of EEG uses
  2. Evidence for REM Sleep: Dement and Kleitman monitored sleep patterns of 9 pps. REM sleep correlated with dreaming and brain activity varied according to how vivid the dreams were. Ppts woken during dreaming reported accurate recall of their dreams. This suggests REM is an important part of the ultradian sleep cycle
  3. SAD practical application: phototherapy is a treatment involving a lightbox that simulated light in the morning and evening (to reset melatonin levels) This relieves symptoms in up to 60% sufferers (Eastman et al)

Limitations

  1. Weakness of using EEG’s
  2. Phototherapy placebo effect: SAD study also recorded placebo effect of 30%, questioning the real value of phototherapy.
  3. Poor methodology in Stern and McClintock study: period synchronisation could be due to other confounding variables e.g.stress, changes in diet, chance. Also women self-reported onset of their own cycle (so findings may be inaccurate)
  4. Use of animal studies: our knowledge of the role of pheromones is based on animal research, role may be different in humans.
52
Q

Give an example of an endogenous pacemaker.

A

The Superchiasmatic Nucleus (SCN) = Tiny bundle of nerve cells located in the hypothalamus in both hemispheres that helps maintain sleep/wake cycle

53
Q

How exactly does the SCN help maintain the sleep/wake cycle?

A

Nerve fibres from the eye cross at the optic chiasm on their way to the visual cortex. The SCN lies just above the optic chiasm and receives info about light (exogenous zeitgeber that influences sleep) from this structure.

54
Q

Give an example of research that shows the influence of the SCN on the sleep/wake cycle

A

DeCoursey et al (2000)

Procedure: Destroyed SCN connections in brains of 30 chipmunks, which were returned to batural habitat and observed for 30 days.

Results: Their sleep/wake cycle disappeared and many were killed by predators.

55
Q

How is the pineal gland/melatonin linked to the SCN and the sleep/wake cycle?

A

Pineal gland = SCN passes info to pineal gland, which increases production of melatonin

Melatonin: Hormone that induces sleep and is inhibited during periods of wakefulness.

56
Q

What would happen if we didn’t have exogenous zeitgebers?

A

The free-running biological clock would continue to ‘tick’ in a cyclical patten (like in Siffre’s study). Zeitgebers reset the sleep/wake cycle. ***

57
Q

Outline a study that showed the effect of light on the sleep/wake cycle

A

Campbell and Murphy

Procedure: Woke 15 ppts at various times and shone a light on the backs of their knees.

Results: Produced a deviation in sleep/wake cycle

58
Q

How can social cues have an influence on the sleep/wake cycle?

A
  1. Adult-determined mealtimes and bedtimes help maintain a babies sleep-wake cycle as most babies are entrained at around 6 weeks
  2. Research shows adapting to local times for eating and sleeping (not responding to own’s own hunger/fatigue) entrains circadian rhythms and tackles jet lag.
59
Q

Evaluate research into endogenous pacemakers and exogenous zeitgebers

A

Strengths
1. Use of lab experiments in chipmunk study (scientific)

Limitations

  1. Generalising: Results from animals can’t be generalised to humans
  2. Ethical issues: Chipmunks were deliberately exposed to great harm (where some were eaten)
  3. Influence of exogenous zeitgebers may be overstated: studies found that individuals who live in Arctic regions show normal sleeping patterns despite prolonged exposure to light
  4. Methodological issues in Campbell and murphy study: pps may have been exposed to some light (a major confounding variable) and isolating only 1 exogenous zeitgeber doesn’t give insight into the many other zeitgebers that influence sleeping.
  5. Interactionist approach: Endogenous pacemakers and exogenous zeitgebers interact in real life. Total isolation experiences (e.g. Siffre’s study) is very rare and is an unrealistic view of how the sleep/wake cycle works.