Biopsych 2 Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What is localisation of function?

A

The principle that specific functions have specific locations within the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Franz galls theory of phrenology?
What did Pierre flourens do?

A

The study of the structure of the skull to determine a persons character and capacity
Used animal experiments to demonstrate main divisions of the brain were responsible for different functions.
Since the 19th cent, techniques have grown considerably

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the motor cortex:
Role
Location

A

Responsible for generation of voluntary movements
Located in frontal lobe along pre central gyrus
Motor cortex on each side of brain- left responsible for muscles on right vice versa
Diff parts of motor cortex control diff body parts and they are logically offered (eg part that control foot is next to part that controls leg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the somatosensory cortex?
Located?

A

Detects sensory events in diff parts of the body
Located in parietal lobe along the post central gyrus
Uses sensory info from skin to produce sensations of touch pressure pain temp and localises it to specific regions of body
Like motor cortex, one on each side and cross wired

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the post central gyrus?

A

Area of cortex dedicated to processing of sensory info related to touch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

where is the primary visual center of the brain?
where does visual processing actually begin? then where does it go?

A

in the visual cortex in the occipital lobe. visual cortex spans both hemispheres (left receives info from right vf vice versa)
begins in retina where light strikes photoreceptors. nerve impulses are then transmitted to brain by optic nerve
some nerve impulses then travel to parts of brain to be involved in coordination of circadian rhythms but most terminate in thalamus which passes info onto visual cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the auditory center? where is it? describe the auditory pathway

A

concerned with hearing
mostly lies within temporal lobes on both sides in the auditory cortex.
pathway starts in cochlea where sound waves are converted to nerve impulses which travel to auditory cortex by auditory nerve
first stop is brain stem where basic decoding happens, then thalamus where further processing occurs. ends at auditory cortex which recognises sound and generates response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the 2 language centers?

A

broca’s area and wernicke’s area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is broca’s area?

A

posterior portion of left frontal lobe
critical for speech production
discovered by paul broca due to patient who could only say ‘tan’ but could understand speech. also studied others with similar problems and lesions in left frontal hemisphere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is wernicke’s area?

A

posterior portion of the left frontal lobe
critical in speech understanding
his patients could speak but not understand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what did wernicke propose?

A

language involves separate motor and sensory regions.
motor region in brocas is close to area that control mouth, tongue, vocal cords.
sensory region in wernicke’s is close to part of brain responsible for auditory/visual input
there is a neural loop between brocas and wernickes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

evaluation of localisation of function and language centres

A

-
not everyone agrees functions are localised eg equipotentiality theory (lashley 1930) suggests basic motor and sensory functions are localised but more complex arent. says intact areas of cortex can takeover responsibilities following injury. says effect of damage is determined by extent not location

research suggests how areas communicate is more important that which region controls specific process. wernicke claimed areas are interdependent. eg french neurologist described case where loss of ability to read led to damage to connection between visual cortex and wernickes area. suggests complex behaviours move through diff structures before response produced. damage to connection between any 2 points in this process leads to impairments similar to damage to localised brain region for that specific function

individual diff- eg bavelier et al 1997 did silent reading study and found variability in patterns of activity between people. found activity in right temp lobe, left front, temp, occip lobes. gender differences- harasty et al 1997 found larger brocas and wernickes in women due to greater use of language

language may not be confined to brocas- bronkers et al 2007 examined lesions using MRI and found other areas may have contributed to reduced speech. significant as lesions in brocas usually cause temporary disruption- suggests speech is complex and network not localised

+
support for language centres from aphasia studies eg brocas and wernickes. expressive aphasia- cant produce language shows brocas is important for speech. receptive aphasia- cant understand language shows wernickes is important in comprehensive

case study evidence- Gage, Tan, HM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is hemispheric lateralisation?

A

the fact that 2 halves of the brain arent entirely alike and each hemisphere has functional specialisms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how are the 2 hemispheres attached? what does this mean?

A

the corpus collosum ( a bundle of nerve fibers that connect the 2 halves)
means info can be sent from one half to other and we can for example, talk about things experienced in right hemisphere despite left for language

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is a commisurotamy?

A

cutting through the corpus collosum as treatment for severe epilepsy.
prevents violent electrical activity from crossing from one hemisphere to another. known as split-brain patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

describe Sperry and Gazinga’s research 1967

A

studied capabilities of split-brain patients. sent info to one hemisphere to study hemispheric lateralisation as corpus collosum is cut so info cant travel to other spot
-ppt stares at dot (so info only goes to 1 visual field)
- picture shown to 1 visual field for 1/10 second (so cant move eyes)
-found that picture shown in rvf could be described but not drawn (info goes to left hemisphere-left for language)
- picture shown to lvf could draw with left hand (controlled by right hemisphere). can only describe when theyve drawn it
- same concept with holding something in left/ right hand

17
Q

what have we learnt from split brain reserach?

A

differences between hemispheres (left for language and right for visual-spatial processing and facial recognition)
but hasnt shown that brain is organsied into discrete regions w specific tasks and instead suggests connectivity between diff regions is as important as operation of diff parts

18
Q

evaluate lateralisation

A

assumed that it leads to increased neural processing capacity- using only one hemisphere to engage in task means other is free to engage in another function but little evidence for this. rogers et al 2004 found that (in chickens), lateralisation is associated w ability to perform 2 tasks simultaneously- does provide some evidence that lateralisation increases efficiency

lateralisation changes w age- lateralised patterns in younger people seem to become bilateral when older. szaflarski et al 2006 found language is more lateralised to left when getting older but at 25, lateralisation decreases each decade. may be cuz using other hemisphere may compensate for age related decline in functions

19
Q

evaluate split brain reserach

A

gazzinga 1998 suggests some early discoveries have been disconfirmed. eg originally suggested right cant handle any language but case studies have opposed this (JW learnt to speak out of right)

limitations of the actual research- many studies only have around 3 ppts. conclusions drawn from individuals w confounding physical disorder.

20
Q

evaluate Sperry and Gazzinga’s study

A

+
scientific - consistent results, same task, shown for 1/10s
applications- develop treatments, understand roles of hemispheres
high internal validity- presentation of stimulus to one hemisphere means most likely measuring what each hemisphere does
good ethics- corpus collosum already cut-no manipulation of IV, all consented, could withdraw, fully informed

-
small, atypical sample so not generalisable
gazzinga- discoveries disproved
lack of controls- no valid control group, some on medication, some had more disconnection than others
low ecological validity- irl people have unrestricted view so info not selectively delivered to one hemisphere

21
Q

what is brain plasticity?

A

the brain’s ability to change and adapt as a result of experience.

22
Q

what is functional recovery?

A

moving functions from damaged area of the brain after trauma to another area

23
Q

what types of experience can change neural organisation?

A

plasticity as a result of life experience- gain new experiences means nerve pathways that are frequently used develop stronger connections and ones barely used die. this pruning allows brain to adapt. natural decline with age so ways of reversing this have been found eg Boyke et al 2008 found evidence of brain plasticity in 60 year olds (increased grey matter in visual cortex when learnt to juggle)

playing video games- complex cognitive and motor demands. Kuhn et al 2014 compared control w group that was trained for 2 months 30 mins a day at video game and found increased grey matter in various brain areas that wasnt found in control

meditation- davidson et al 2004 compared 8 monks with 10 volunteers with no meditation experience. both fitted with electrical sensors and asked to meditate. more gamma wave (coordinate neuron activity) activity in monks. students showed slight increase in gamma. so makes short term changes as well as long term (monks had more before experiment

24
Q

what are the mechanisms for functional recovery?

A

regenerative developments in brain due to its plasticity
neural masking and stem cells

25
Q

what is neural unmasking?

A

wall 1977 discovered dormant synapses (blocked)
normally would be ineffective because rate of neural input is too low for them to be activated
increased rate of input that occurs when surrounding area is damaged can unmask them
this gives way to the development of new structures over time.

26
Q

how can stem cells lead to recovery of a stroke?

A

unspecialised cells that can take on characteristics of nerve cells
diff views of how this works:
cells implanted into the brain can directly replace dead cells
or
transplanted stem cells can secrete growth factors that rescue injured cells
or
transplanted cells form a neural network which links uninjured brain site where stem cells are made with the damaged region of the brain

27
Q

evaluation of plasticity

A

research support from animal studies- kempermann et al 1998 found increased no of neurons in hippocampus of rats in complex environments compared to in lab cages
research support from human studies- maguire et al 2000 studied london taxi drivers to discover whether changes in brain could be detected as a result of extensive navigation experience. used MRI to calculate amount of grey matter in taxi drivers brains and control. posterior hippocampus of taxi drivers were significantly larger. volume was positively correlated with time theyd been driving

28
Q

evaluation of functional recovery

A

Tajiri et al 2013 assigned rats w brain injury to 2 groups. 1 received transplants of stem cells into affected region. control had injection into brain that contained no stem cells. 3 months later, brain stem of rats w stem cells showed development of neuronlike cells in injured area. also, stream of stem cells migrating into brains injured site. not case for control
age diff- plasticity reduces with age. so would think could not recover after brain injury but studies have suggested that even abilities thought to be fixed in childhood can be modified w intense training. elbert et al 2001 concluded capacity for neural reogranisation is greater in kids than adults as adults need more practice (+ or -?)

29
Q

what is a post mortem examination?

A

see underlying neurobiology of particular behaviour. when a person dies, you can examine brain to look for abnormalities not found in control that may explain behaviour in life. eg used on Tan and HM- identified language and memory areas) can also see depression from post mortem (reduced no of glial cells(provide support and insulation in neurons) in frontal cortex)

30
Q

what is an fMRI?

A

measure changes in brain activity whilst performing task. measures blood flow to areas of brain indicating neural activity. more active= more oxygen demand= increased blood flow
can be used to produce maps of brain areas involved in particular activity
ppt asked to do task for 30s then control state for 30s to see which areas are activated due to stimulus

31
Q

what is an EEG? electroencephalogram

A

measures electrical activity in the brain
electrodes placed on scalp detect small electrical charges due to brain activity. electrical signals graphed over period of time produces an EEG
can detect brain disorders eg epilepsy (spikes of activity)
4 basic patterns- alpha, beta, delta, theta. awake but relaxed- alpha, physiologically aroused- beta, REM sleep- beta, sleep- delta and theta

32
Q

what is an ERP?

A

small voltage changes triggered by events or stimuli.
difficult to pick out due to all other electrical activity happening
show stimuli repeatedly then avg responses together- any extraneous activity will not appear repeatedly
ERPs can be divided into 2 categories: waves occurring in first 100millisecs after stimuli presented are called sensory (reflect initial response to physical characteristics of stimulus)
ERPs after 100millisecs reflect how subject evaluates stimulus and are called cognitive (demonstrate info processing)

33
Q

evaluate post mortem examination

A

+
provides foundation for early understanding of key brain processes
broca and wernicke used it to find links between language and brain
improve medical knowledge and help create hypotheses for research
deeper regions such as hippocampus can be seen
high spatial resolution

-
damage found may not be linked to deficits in behaviour
ethical issues of consent eg HM couldnt
people die in varying circumstances and stages of disease
length of time between death and post mortem (poor temp resolution), age of death and drug treatment are confounding variables

34
Q

evaluate fMRI

A

+
no radiation- risk free, non invasive, straight forward
high spatial resolution- clear pic of localisation

-
expensive
person has to stay very still for clear image
poor temporal resolution- 5s delay between image and neuronal activity

35
Q

evaluate EEG

A

+
invaluable in diagnosis eg of epilepsy- spikes of electrical activity
contributed to understanding of stages of sleep
high temporal resolution- takes readings every millisecond
cheaper than other techniques so more accessible

-
generalised nature of info received- 1000s of neurons
isnt useful for pinpointing exact source of neural activity as electrical activity is detected in diff regions of brain at same time
poor spatial resolution
superficial data- doesnt penetrate into brain

36
Q

evaluate ERP

A

+
more specific than EEG
high temporal resolution
researchers can identify diff ERPs and describe role of them in cognitive functioning
cheap
non-invasive

-
lack of standardisation- difficult to confirm findings
background noise and extraneous material must be completely eliminated to establish pure data which isnt easy to achieve
superficial data- cant penetrate into brain
poor spatial resolution