biopsych Flashcards
localisation of function AO1
The brain has two symmetrical hemispheres which control some of our physical and psychological functioning
eg language linked to the left hemisphere
- theory that different areas of the brain are responsible for different processes/behaviours
(broca + wernicke)
cortex of both hemispheres divided into 4 lobes - occipital, parietal, temporal, frontal lobe
frontal lobe = motor area controlling voluntary movement of the opposite side of the body
- damage of this leads to loss of control over fine movements
both parietal lobes = somatosensory area processes sensory information from the skin
seperated from motor area via central sulcus
occipital lobe = visual area processes and receives visual information
- right visual field (of each eye) sends info to left visual cortex and left visual field sends info to right visual cortex
damage to hemisphere -> blindness or partial blindness
temporal lobes = auditory area analysing speech based information
damage -> partial hearing loss
language restricted to left hemisphere:
damage to brocas area - left frontal lobe (brocas aphasia) -> speech lacks fluency with conjunctions (and/the)
damage to wernickes area (left temporal lobe) responsible for language understanding -> nonsense words
localisation of function eval - evidence from neurosurgery
Evidence from neurosurgery:
neurosurgery targets parts of the brain involved in mental disorders
eg: cingulotomy for OCD
dougherty et al reported on 44 individuals with OCD, 32 weeks post surgery = 30% has successful response to surgery and 14% a partial response
- suggests behaviours linked to serious mental disorders are localised and can be treated by isolating that part of the brain causing the issue
+ case study of phineas gages accident affecting frontal lobe causing personality shift
- first form of evidence linking frontal lobe to personality
BUT is a case study so isnt generalisable to all (extreme scenario)
localisation of function eval - language may not just be localised to wernicke/broca
language may not be localised to just wernicke and brocas area:
dick and tremblays interview found only 2% of researchers think wernicke/brocas area is entirely involved in language control
advances in brain imaging like fMRIs means neural processes in the brain can be studied more objectively
language function distributed holistically in the brain - not isolated to W/B areas
Even found in right hemisphere
contradicting localisation theory
localisation of function eval - evidence from brain scans + counter
Evidence from brain scans:
peterson et al used brain scans to demonstrate how wernickes area was active in listening tasks and brocas during reading tasks
objective measures = valid evidence
+ other studies have shown that semantic memory and episodic memories are linked to different parts of the prefrontal cortex
BUT lashley removed different areas of the cortex in rats learning a maze and found no difference in the rats ability to learn the route
suggests learning requires every part of the cortex rather than being confined to one area
- learning = more holistic disapproving localisation of function theory
hemispheric lateralisation AO1
idea that the two halves of the brain are functionally different and that each hemisphere has functional specialisations
language = lateralised as broca+wernicke’s area = left hemisphere (B= left frontal W= left temporal)
Some functions arent lateralized:
motor area appears in both hemisphere but is contralateral
vision = contralateral (right hemisphere controls left side of body)
+ ipsilateral - LVF of BOTH eyes connected to right hemisphere and RVF of BOTH eyes connected to left hemisphere
- slightly different perspective = greater depth perception
Sperry - split brain research on 11 ppts undergone split brain surgery where corpus callosum was removed (prevents communication between hemispheres)
presented info to one hemisphere only by flashing a stimulus in either of the visual fields
Presenting a word (cat) in the left visual field (connected to RH) meant the patient wasn’t able to verbally express what he saw as the language centres are located in the LH.
However, they were able to draw a picture of a cat, using their left arm (connected to their RH)
Concluded some functions are lateralised eg left hemisphere is more verbal
hemispheric lateralisation eval - research support + counter
Research support:
fink et al used PET scans to identify active areas of brain during visual processing tasks
global elements of an image (whole forest) showed activity in RH more but looking at finer details (one tree) showed activity in LH
suggest that in connected brains some aspects of visual processing show hemispheric lateralisation
but lowered validity as research only looks at visual processing
BUT
Nielsen et al- analysed brain scans from 1000+ people 7–29 years old
people used certain hemispheres for certain tasks
but no evidence of a dominant side or LH as analyser and RH as synthesiser
suggesting notion of left and right brained people is incorrect
hemispheric lateralisation eval - hard to establish causal relationships
a limitation of Sperry’s research is that it is hard to establish causal relationships.
For example, the control group he used can be described as neurotypical, meaning none of those participants had epilepsy.
This is a problem because this becomes a confounding variable because any differences Sperry found between the split-brain participants and the control group may be a result of the epilepsy
Therefore, it is hard to determine whether the unique features of the participants’ cognitive processing abilities were actually due to hemispheric lateralisation or not.
+ used quasi experiment so sperry didnt manipulate any variables - low internal validity
Small sample size and age could be a confounding variable
hemispheric lateralisation eval - adaptive + counter
Adaptive:
allows 2 tasks to be performed simultaneously - useful for animal survival instincts
roger et al showed lateralised chickens could find food and watch predators but normal chickens couldnt
BUT not adaptive as
it would not benefit an individual for their brains to be too fixed in structure in case of injury
non-specialised areas in opposite hemispheres can take over functions, following damage caused by illness or trauma = plasticity
lateralized functions are more flexible rather than fixed and brain plasticity is more important as it can deal with brain damage
plasticity AO1
Brain plasticity is the ability to form neural connections in response to new demands on the brain
synaptic connections increase as a child and decrease in adulthood by strengthening frequently used ones and deleting rarely used connections = synaptic pruning
maguire studied taxi drivers brain after study of the knowledge
found more grey matter in prosterior hippocampus than control associated with navigation
Found preparation for “ the knowledge test “ altered brain structure
+ positive correlation with time spent as a driver and how pronounced brain changes were
+ draganski - medical students 3 months before+after exam showed changes in prosterior hippocampus and parietal cortex due to learning
plasticity eval - negative behavioural consequences
Negative behavioural consequences:
60-80% of amputees experience phantom limb syndrome causing extreme discomfort due to cortical reorganisation in the somatosensory cortex
brains ability to adapt to damage isnt always useful
BUT useful for language learning where the brain molds to increase the size of the left interior parietal cortex enabling bilinguacy
suggests plasticity isnt useful when coping with unatural issues but beneficial in most cases
plasticity eval - lifelong plasticity
Lifelong plasticity:
plasticity usually decreases with age
bezzola found 40 hours of golf training of 40-60 year olds led to increased motor cortex activity with fMRIs compared to control
plasticity can help reduce age related cognitive decline
research can be used to treat patients with neurodegnerative diseases like alzheimers
increasing neural connections acts as treatment decreasing rate of cognitive decline
a
plasticity eval -affected by environmental change
Affected by environmental change:
SCN regulates the sleep/wake cycle
shrinks in all animals during spring and expands throughout autumn (includes humans) (Tramontin and Brenowitz)
This enables better adaption to day length
BUT research mainly on songbirds - question whether cycles are the same in birds and humans
as humans have less adaptive pressure to develop biological mechanisms to adapt to environment
more research needed on humans and plasticity linked to environemental change
functional recovery AO1
form of plasticity occuring after trauma
transfer of roles from damaged areas to undamaged by transfer of synaptic connections close to area of damage
fast process post trauma (spontaneous recovery) but slows down as time goes on
secondary neural pathways revived to enable functioning as usual + structural changes(doidge et al)
- axonal sprouting = new nerve endings connect with undamaged ones forming new neural pathways
- denervation supersensitivity = neurones with similar roles aroused to compensate for the ones lost (but increases sensitivity to pain)
- recruitment of homologous areas on opposite side of the brain = some tasks still perform eg: brocas area damaged on LH can still decode language from RH
functional recovery eval - real world applications
Real world applications:
understanding processes of plasticity -> improvements in neurorehabilitation
axonal growth via functional recovery encourages new treatments to be trialed
eg: constraint induced movement recovery used on stroke patients where they continue to use the affected body part while the unaffected body part is restrained
research used to improve treatments for patients using functional recovery
allows medical professionals to develop new therapeutic interventions to help patients following brain damage
functional recovery eval - recovery affected by cognitive reserve
cognitive reserve affects recovery:
level of education affects recovery rates
schneider et al found longer time spent in education (linked to cognitive reserve) led to faster recovery
+ greater chances of disability free recovery
40% of those achieving DFR had spent 16+ years in education compared to only 10% with DFR with less than 12 year education
BUT results may be due to chance or other factors such as health as 10% still achieved DFR even with less cognitive reserve
functional recovery eval - validity issues
Validity issues:
banerjee found stem cell treatment on 5 patients with TACS led to recovery in all patients compared to 4% usually
BUT, small sample size as only 5 ppts plus no control group to compare to (difficult to match patients based on extent of damage)
results cannot be generalisable (similar to politician gabby giffords case where she was longitudinally studied but was a one off case - shot point blank)
rich data obtained which was useful for brain plasticity but cannot explain all people -
temperament may have affected her recovery = low external validity
fMRI
fMRI - detects changes in oxygen levels in blood flow occurring due to activity within the brain
active areas of brain require more oxygen directing greater blood flow to area in use
fMRI adv
no radiation (unlike PET) so risk free + non invasive
images also have high spatial resolution (detailed)
provides a clear picture of brain activity
fMRI disadv
expensive compared to other methods
low temporal resolution due to lag so fmri isnt representative of in the moment brain activity
EEG
record of impulses produced by brain activity on electrodes
can detect neurological abnormalities such as epilepsy, insomnia or tumours
EEG adv
high temporal resolution (unlike fmri)
+ diagnoses many sleep disorders + tumours
EEG disadv
cant pinpoint exact source of neural activity (results from millions of neurones)
ERP
ERP - electrophysiological response of the brain to a specific sensory/cognitive/motor event
ERP formed from EEGs leaving behind brainwaves triggered by event (rather than broad area)
ERP adv
more specificity of neural processes compared to EEGs
high temporal resolution (compared to fmri)
used to understand working memory