BIOM2011 (2022) Exam MCQs Flashcards

1
Q

The human eye can focus on an object through a part of the eye or the whole eye

A

The whole eye can change shape on demand to accommodate the focus needs

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2
Q

How is the frequency of sound encoded in the cochlea

A

place coding, the position of the responding hair cells depends on the frequency

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3
Q

An efference copy is the copy of what

A

motor commands sent to predict sensory feedback

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4
Q

Why is colour vision lacking in the dark

A

Due to reduced visual pigments being more sensitive to colour

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5
Q

What is happening in hair cells’ signal transduction

A

Mechanosensitive K+ channels are opening or closing

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6
Q

How do sensory receptors inhibit neighbouring receptors

A

By improving the signal to noise ratio

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7
Q

What are Primary sensory neurons

A

They are afferent neurons which can detect sensory stimuli and relay the information to the brain

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8
Q

What’s The major difference between ion channels and ion pumps

A

their specificity for moving particular ions

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9
Q

If the closure of the K+ channels of the sino-atrial node slowed down, the effect on the baseline phase of the cell’s action potential would be

A

The baseline would depolarize more slowly to threshold

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10
Q

At high heart rates (e.g., 150 bpm), the ventricles still fill with blood because

A

filling is accomplished in early diastole

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11
Q

A potential five-fold increase in cardiac output in a person going from a resting state to one of intense exercise suggests what

A

both the stroke volume and pacing rate of the heart must have increased

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12
Q

What are some (four) effects of the parasympathetic nervous system on the heart

A

Slowed closure of K+ channels, decrease inward Ca2+ current, weakened atrial contraction and slowed pacemaker activity

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13
Q

What is the major difference between skeletal and cardiac type excitation-contraction coupling

A

a physical coupling of the voltage sensor and Ca2+ release channel in skeletal muscle, and a chemical coupling in cardiac muscle

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14
Q

Which immune component is primarily involved in the development of serum sickness

A

IgG

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15
Q

During an immune response to viral infection in the lung, what naïve T cells would most likely be activated

A

lymph node

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16
Q

On repeat exposure to a pathogen, a patient is identified with high circulating levels of IgM antibody specific for the pathogen. This is most likely caused by

A

lack of isotype switching

17
Q

Within inflamed tissues, which of the following molecules would directly result in chemotaxis of immune cells?

A

Complement

18
Q

Many years ago, William Coley found that injection of bacterial extracts would often clear many types of tumour. This technique was most likely successful because

A

the activation of dendritic cells was enhanced by the bacterial extracts

19
Q

What are the mechanisms for clearance of released neurotransmitters from the synaptic cleft?

A

re-uptake into surrounding glial cells by specific transporters, simple diffusion in extracellular space, rapid breakdown by specific enzymes and endocytosis of unchanged neurotransmitter

20
Q

Can electric and chemical neurotransmitters be modulated in many ways

A

Electrical neurotransmission can be modulated in many ways, and chemical neurotransmission has limited mechanisms for modulation

21
Q

In neuronal axons where are Voltage-gated sodium channels concentrated at

A

nodes of Ranvier

22
Q

What are the dendrites of neurons

A

where most neurotransmitters are received by neurons

23
Q

What is the correct relationship between current (I), voltage (V), and resistance (R)

A

V = I x R; Ohm’s Law.

24
Q

What does Long-term potentiation of synaptic transmission require

A

NMDA receptor activation, calcium ion influx, and protein kinase activation

25
Q

Where are growth hormone receptors found in the body

A

They’re found in most tissues in the body

26
Q

How is growth hormone regulated

A

By GH releasing hormone and somatostatin via G-protein coupled receptor signalling

27
Q

What mechanism is involved in mediating the increased prolactin secretion during lactation

A

Increased tyrosine hydroxylase activity and expression

28
Q

What is the pairing of hypothalamic releasing factor and anterior pituitary gland hormone

A

thyrotrophin-releasing hormone and thyroid-stimulating hormone.

29
Q

Why do oxytocin levels increase during birth

A

due to a positive feedback loop between the uterus and hypothalamus

30
Q

What is oxytocin

A

is a small peptide hormone

31
Q

What does oxytocin promote in lactation

A

promotes breast milk ejection for the suckling infant

32
Q

What can stimulate the release of growth hormone

A

Exercise, low blood fatty acid concentrations, low circulating insulin like growth factor 1 concentrations and high plasma amino acid levels

33
Q

What are the precursors that polymerize to form the keratin network on the surface of the epidermis?

A

keratohyalin and eleidin

34
Q

What motor protein is responsible for the movement of cilia?

A

dynein

35
Q

What is the cell type in the epidermis responsible for sensing touch and temperature

A

The Merkel cell

36
Q

Within the intestinal epithelium, regeneration and cellular identity of the different types of epithelial cells is mediated by induction of which signalling pathway

A

Wnt and Notch signalling pathways

37
Q

What kind of cells produce mucin and what is the function of this substance

A

goblet cells; to create a layer that traps external particles

38
Q

Which hormone produced in the hypothalamus is responsible for increasing water resorption in the kidney and what is the mechanisms of action for this increased water permeability

A

vasopressin; it causes aquaporin to recycle to cell surface allowing more water molecules to enter the cells

39
Q

What respiratory epithelia region is lined with simple squamous epithelial cells?

A

The alveolus