Biology of Aging Flashcards

1
Q

By age 70 your cardiac output is reduced by….?

A

70%

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2
Q

Should left ventricle ejection fraction be changing in the aging population?

A

NO

If the ejection fraction is changing this is pathological.

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3
Q

What occurs to pt heart rate and maximum heart rate in the elderly?

A

Heart rate decreases along with maximum heart rate.

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4
Q

What is the most common valvular lesion in the eldlerly?

A

Aortic Stenosis!

Most common murmor.

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5
Q

What occurs to elderly lungs?

A

Alveoli dialate - Decreased gas
Lungs more rigid
V/Q mismatch due to increased alveolar arterial O2 gradient.

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6
Q

Is carbon dioxide excretion impaired with age?

A

NO

CO2 accumulation is pathological and must be further investigated.

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7
Q

As we age, does Total lung capacity change?

Inspiratory capacity?

A

Total lung capacity will not change

inspiration capacity decreases

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8
Q

True or false, max breathing capacity can decrease about 80%?

A

true.

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9
Q

Are a decline in liver function tests with age normal?

A

NO

however cytochrome p450 content decreases with age.

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10
Q

Do fluid electrolyte homeostasis change with age?

A

NO

Fluid and electrolyte homeostasis should not change with age!

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11
Q

Should incidence of urinary incontinence change with age?

A

Yes, increased incedence of urinary incontinence occurs after age 80.

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12
Q

Age related neuronal loss is most common where?

A

In the cerebellum and cerebral cortex

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13
Q

A decrease in Acetylcholine is related to what mental disorder?

A

Dementias

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14
Q

IS it common for executive thought function as well as working and episodic memory to decline with time?

A

Yes this is normal and occurs more dramatically over 70.

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15
Q

Is it common for the abiliy to recognize familiar object and faces to degress over time?

A

No

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16
Q

What are the reversible causes of dimentia?

A
Drugs
Emotional disorders
Metabolic or endorcrine disorders
Eye and ear dysfunction
Nutritional deficiencies
Tumors and trauma
Infections**
Arteriosclerosis
17
Q

50% decrease in glomeruli true or false?

A

True

18
Q

Brain can lose up to 10% in weight volume true or false?

A

True

19
Q

What is presbyopia?

A

Farsightedness because of change in lens and iris.

20
Q

What is presbycusis?

A

Irreversible sensorineural loss
(hearing loss)
Is common

21
Q

What is the percentage of cerebral blood flow decrease by age 70?

A

20% decrease