Biology Chapter 12: Genetics and Evolution Flashcards
Chromosomes
contain genes in a linear sequence
Alleles
Alternate forms of a gene
dominant allele
masks recessive allele and requires only one copy to be expressed.
Recessive allele
Requires two copies to be expressed - masked by a dominant allele
genotpe
combination of alleles one has at a given genetic locus.
phenotype
observable manifestation of a genotype
Penetrance
the proportion of a population with a given genotype.
Medel’s first law of segregation
an organism has two alleles for each gene, which segregates during meiosis, resulting in gametes carrying only one allele for a trait.
Mendel’s second law of independent assortment
state that the inheritance of one allele does not influence the probability of inheriting a given allele for a different trait.
Griffith experiment
demonstrated the transforming principle, converting non-virulent bacteria to virulent bacteria by exposure to heat-killed virulent bacteria.
Avery-MacLeod-McCarthy experiment
demonstrated that DNA is the genetic material because degradation of DNA led to a cessation of bacterial transformation
Hershey-Chase
confirmed that DNA is the genetic material because only radiolabeled DNA could be found in bacteriophage-infected bacteria.
Gene pool
All of the alleles in a given population.
Point mutations
substitute one nucleotide for another
Frameshift mutation
moving the three letter transcriptional reading frame
Silent mutation
no effect on the protein