Biology- Animal Form and Function 3 Flashcards
Endocrine System
Anterior Pituitary
mainly regulates hormone production by other glands–itself regulated by hypothalamus
- Direct Hormones
- Tropic Hormones
Endocrine System
Anterior Pituitary (Direct hormones)
directly stimulate target organs
- growth hormone (HGH)- aka somatotropin; stimulates bone and muscle growth
- prolactin- stimulates milk production in females
- endorphins- inhibit perception of pain (technically a neurohormone)
Endocrine System
Anterior Pituitary (Tropic hormones)
stimulate other endocrine glands
- Adrenocorticotrophic hormone (ACTH)- stimulates adrenal cortex => release glucocorticoids-involved in regulation of metabolism of glucose
- Thyroid-stimulating hormone (TSH)-stimulates thyroid gland (increase size, cell #) to release thyroid hormone (T4 and T3)
- Luteinizing hormone (LH)- females-stimulates formation of **corpus luteum **/ males- stimulates interstitial cells of testes to produce testosterone
- Follicle-stimulating hormone (FSH)-females- stimulates maturation of ovarian follicles to secrete estrogen/ males- stimulates maturation of seminiferous tubules and sperm prod
Endocrine System
Posterior Pituitary
does not synthesize hormones, stores ADH and oxytocin produced by hypothalumus
- antidiuretic hormone (ADH/vasopressin) increases reabsorption of water by increasing permeability of nephron’s** collecting duct** => water reabsorption and increased blood volume and pressure. Coffee blocks ADH.
- oxytocin-secreted during childbirth- increases strength of uterine contractions and stimulates milk ejection
Endocrine System
Pineal glands
secretes melatonin- plays role in circadian rhythm
Endocrine System
Thyroid
located on ventral surface of trachea
-
Thyroxine (T4) and Triiodothyronine (T3)
- derived from tyrosine and necessary for growth and neurological development in children and increase basal metabolic rate in body (negative feedback on TSH)
- HYPOTHYROIDISM- undersecretion => low heart rate and respiratory rate
- HYPERTHYROIDISM- oversecretion => increased metabolic rate and sweating
- both lead to goiters
- **Calcitonin **(tones down Ca2+) in blood
- decreases plasma Ca2+ by inhibiting its release from bone
- decreases osteoclast activity and number
- Disorders of the thyroid include **anchondroplasia **(AD; dwarfism) and **progeria **(AR; premature aging)
Endocrine System
Parathyroid
four pea-shaped structures attached to back of thyroid
-
Parathyroid hormone (PTH)- antagonistic to calcitonin
- *Raises Ca 2+ *concentrations in blood by stimulating release from bone
- increases osteocte absorption of Ca + P from bone; stimulates osteoblast proliferation
- increases renal Ca reabsorption
- *Raises Ca 2+ *concentrations in blood by stimulating release from bone
Endocrine System
Thymus
involved in immune response
- secretes thymosins that stimulate lymphocytes (WBCs) to become T-cells (identification and destroying of infected body cells)
Endocrine System
Adrenal Gland
on top of kidneys and consist of:
- glucocorticoids (cortisol and cortisone)- raise blood glucose levels (stimulates gluconeogenesis in the liver); affect fat and protein metabolism; stress hormones
-
mineralcorticoids (aldosterone)- increases reabsorption of Na+ and excretion of K+
- cause passive reabsorption of water in nephron => rise in blood volume/pressure
- cortical sex hormones (androgens = male sex hormone) effect is small due to testis
Endocrine System
Adrenal Medulla
_Epinephrine and norepinephrine _ (adrenaline and noradrenaline)- “fight or flight”- the catecholamines
- “fight or flight” (*sympathetic *N.S.); considered stress hormones
- glycogen => glucose, vasoconstrictor to internal organs and skin but vasodilator to skeletal muscle, increased heartbeat
Endocrine System
Pancreas
both exocrine and endocrine; has bundles of cells called **islet of Landerhans **which contains two cell types:
- alpha cells secrete **glucagon **(alpha “active”): catabolic, released when energy charge is low; raises blood glucose levels
- stimulates liver to glycogen => glucose
- beta cells secrete insulin (beta “bumming”): anabolic, released when energy charge is high; lower blood glucose levels
- stimulates liver (and most other body cells) to absorb glucose
- Liver + muscle cells: glucose => glycogen; fat cells: glucose => fat
- **Somatostatin **is released by delta cells of pancreas; inhibits both insulin and glucagon; possibly increases nutrient absorption time
Endocrine System
Testis
testosterone- spermatogenesis, secondary sex characteristics
Endocrine System
Ovaries
- Estrogen: menstrual cycle, secondary sex characteristics
- Progesterone: menstrual cycle, pregnancy
Endocrine System
Gastrointestinal hormones
- _Gastrin _ food in stomach, stimulates secretion of HCl
- Secretin small intestine- when acidic food enters from stomach => neutralize aciditiy of chime by secretion of alkaline bicarbonate
- _Cholecystokinin _ small intestine- presence of fats => causes contraction of gall-bladder and release of **bile **(involved in digestion of fats)
Endocrine System: Source
Posterior Pituitary
Hormone, Target, Action
ADH (antidiuretic hormone), kidney, increases absorption of water
Oxytoxin, mammary glands, milk letdown
Endocrine System: Source
Anterior Pituitary (tropic hormones)
hormone, target, action
TSH (thyroid stimulating hormones), thyroid, secretion of T4 and T3
ACTH (adrenocorticotropic hormones), adrenal cortex, secretion of glucocorticoids
FSH (follicle stimulating hormones), ovaries and testes, regulates oogenesis and spermatogenesis (both)
LH (luteinizing horomes), ovaries and testes, regulates oogenesis and spermatogenesis (both)
Endocrine System: Source
Anterior Pituitary (hormones)
hormone, target, action
- PRL (prolactin), mammary glands, production of milk
- GH (growth hormones), bone and muscle, stimulates growth
Endocrine System: Source
Anterior Pituitary (hormones)
hormone, target, action
- PRL (prolactin), mammary glands, production of milk
- GH (growth hormones), bone and muscle, stimulates growth
Endocrine System: Source
Pancreas (alpha cells)
hormone, target, action
glucagon, liver, increases blood glucose
Endocrine System: Source
Pancreas (Beta cells)
hormone, target, action
insulin, (liver,muscles,fat), decreases blood glucose
Endocrine System: Source
Adrenal gland (medulla)
hormone, target, action
- epinephrine (adrenalin), (blood vessels, liver, heart), increases blood glucose, vasoconstriction (sympathetic)
- norepinephrine (noradrenalin), (blood vessels, liver, heart), increases blood glucose, vasoconstriction (sympathetic)
Endocrine System: Source
Adrenal gland (cortex)
hormone, target, action
- glucocorticoids (cortisol), general, increases blood glucose
- mineralocorticoids (aldosterone), kidney, increases reabsorption of Na+ and excretion of K+
Endocrine System: source
Thyroid
hormone, target, action
- T4 (thyroxin) and T3 (triidothyronine), general, increases cellular metabolism
- calcitonin, bone, lower blood Ca2+
Endocrine System: Source
Parathyroid
hormone, target, action
- PTH (parathyroid), bone, increases blood Ca 2+
Endocrine System: Source
Testis
hormone, target, action
- testosterone, testes, general, (spermatogenesis, 2nd sex char)
Endocrine System: Source
Ovary
hormone, target, action
- estrogen, (uterus, general), (menstrual cycle, 2nd sex char)
- progesteron, uterus, (menstrual cycle, pregnancy)
Endocrine system: Source
Pineal
hormone, target, action
- melatonin, body, circadian rhythms