Biology Flashcards
Abductor
A muscle that moves a limb away from the center of the body
Absorption
The process by which substances are taken up into or across tissues
Acetylcholine
A neurotransmitter found throughout the nervous system (somatic motor neurons, preganglionic parasympathetic and sympathetic nerves, and postganglionic parasympathetic neurons); metabolized by acetylcholinesterase
Acrosome
The large visible at the head of a sperm cell containing enzymes that degrade the ovum cell membrane to allow fertilization
Actin
A protein found in the cytoskeleton and muscle cells; it is the principle constituent of the thin filaments and microfilaments
Action potential
An abrupt change in the membrane potential of a nerve or muscle caused by changes in membrane ionic permeability; results in conduction of an impulse in nerves or contraction in muscles
Active immunity
An immune response (antibody production or cellular immunity) acquired in response to exposure to an antigen
Active site
Substrate-binding region of an enzyme
Adaptation
The development of characteristics that enable an organism to survive and reproduce in its habitat
Adaptive immunity
Highly specific form of immunity that retains chemical memory of each invader encountered and os able to tailor the immune response to the specific pathogen
Adaptive radiation
The evolutionary process by which one species gives rise to several species, each specialized for different niches
Adductor
A muscle that moves a limb toward the center of the body
Adenine
A purine base present in DNA and RNA; it forms hydrogen bonds with thymine and uracil
Adenine triphosphate (ATP)
A nucleotide molecule consisting of adenine, ribose, and three phosphate moieties; the outer two phosphates are bound by high-energy bonds
Adipose
Refers to fatty tissue, fat-storing tissue, or fat within cells
Aerobic
Refers to a biological process that occurs in the presence of molecular oxygen (O2) or to organisms that cannot live without molecular oxygen
Afferent (sensory) neuron
A neuron that picks up impulses form sensory receptors and transmits them toward the central nervous system
Agranulocyte
Type of leukocyte that does not contain cytoplasmic granules, including lymphocytes and monocytes
Albumin
Protein synthesized in the liver that maintains the oncotic pressure of the blood and serves as a carrier for many drugs and hormones
Allantois
One of four embryonic membranes; it contains the growing embryo’s waste products
Allele
Alternative forms of the same gene coding for a particular trait; alleles segregate during meiosis
Allergy
A type of autoimmunity in which a person’s immune system becomes over activated by common substances in the environment
Alveolus
Basic functional unit of the lung; a tiny sac specialized for passive gas exchange between the funds and the blood
Amino acids
The building blocks of proteins, each containing an amino group, a carboxylic acid group, and a side chain (or R group) attached to the α-carbon
Amnion
The innermost fluid-filled embryonic membrane; it forms a protective sac surrounding the embryos of birds, reptiles, and mammals
Amplification
Characteristic of a signaling cascade, in which the binding of a single peptide hormone to a membrane-bound receptor results in a signal that increases in strength through the signaling cascade
Anaerobic
Refers to a biological process that can occur without oxygen or to organisms that can live without molecular oxygen
Anaphase
The stage of mitosis or meiosis characterized by the migration of chromatids or homologous chromosomes to opposite poles of the dividing cell
Androgen
Any male sex hormone, such as testosterone
Antibiotic
Substance that kills or inhibits the growth of bacteria or fungi (usually by disrupting cell wall assembly or by binding to ribosomes, this inhibiting protein synthesis)
Antibody
Immune or protective protein evoked by the present of foreign substances (antigens) in the body; each antibody binds to a specific antigen in an immune response; also called immunoglobulin
Antigen
A substance that binds to an antibody; may be a foreign or a self-antigen
Antigen-binding region
Portion of an antibody that is specific for a particular antigen; the area of the antibody to which the antigen binds
Aortic valve
One of the semilunar valves, separating the left ventricle from the aorta
Apoptosis
Process by which a cell undergoes programmed cell death in a highly organized manner in response to either external or internal signals
Appendicular skeleton
Peripheral portion of the skeleton consisting of arms, legs, and pelvic and pectoral girdles
Archenteron
The central cavity in the gastrula stage of embryological development; it is lined by endoderm and ultimately gives rise to the adult digestive tract
Arterioles
Small arterial structures that link that arteries to the capillaries
Artery
Thick-walled, muscular blood vessel that generally carries blood away from the heart
Articular cartilage
Cartilaginous coating at the ends of bones that provides a smooth surface for articulation of bones within a joint
Asexual reproduction
Any reproductive process that does not involve the fusion of gametes (such as budding)
Asters
Star-shaped structures that form around the centrosome during mitosis
Atrium
One of two paired structures on either side of the heart, into which blood returning from either the body (right atrium) or the lungs (left atrium) flows
Autocrine
Form of cell-cell communication in which a cell releases a substance that then binds to the membrane of the releasing cell to either inhibit or activate a cellular activity
Autoimmunity
Inappropriate immune response that targets self-antigens
Autonomic nervous system
Subdivision of the peripheral nervous system responsible for involuntary activities, which is further subdivided into the parasympathetic and sympathetic nervous system
Autosome
Any chromosome other than a sex chromosome
Axial skeleton
Midline structures of the skeleton including the skill, vertebral column, and ribcage; provides the central framework of the body
Axon
The long fiber of a neuron; it conducts impulses away from the cell body toward the synapse
Axon hillock
Transition point between the cell body (soma) and the axon of a neuron; the site of action potential initiation
Bacillus
Rod-shaped bacterium
Bacteriophage
A virus that invades bacteria and sometimes uses bacterial RNA and ribosomes to self-replicate
Basophil
Type of granulocytic leukocyte that largely participates in allergic reactions and local inflammation
Bile
A solution of salts, pigments, and cholesterol produced by the liver and stored in the gallbladder; it emulsifies large fat droplets when secreted into the small intestine via the bile duct
Bilirubin
Product of the breakdown of hemoglobin that is modified to a more soluble form in the liver
Binary fission
A type of asexual reproduction characteristic of prokaryotes in which there is equal nuclear and cytoplasmic division
Blastocoel
The fluid-filled central cavity of the blastula
Blastocyst
A mammalian blastula, consisting of the trophoblastic cells and in inner cell mass
Blastopore
Opening of the archenteron to the external environment in the gastrula stage of embryonic development
Blastula
The early embryonic stage during which the embryo is a hollow, fluid-filled sphere of undifferentiated cells
Blastulation
Process by which a solid mass of early embryonic cells, known as the morula, becomes the blastula, a hollow fluid-filled sphere of undifferentiated cells
Bohr effect
Changes in the affinity of hemoglobin for oxygen caused by changes in the environment; when pH is low (increased concentration of hydrogen ions), the oxyhemoglobin dissociation curve shifts right, indicating a decreased affinity of hemoglobin for oxygen and more efficient off-loading of oxygen from hemoglobin
Bolus
An initial dose of medication; in the digestive system, chewed food leaving the mouth, traveling through the esophagus, and entering the stomach
Bone marrow
Central portion of bones, especially long bones, that contains fat and developing blood cells, including erythrocytes, leukocytes, and megakaryocytic
Bone matrix
Organic and inorganic minerals that provide strength to compact bone; organic components include collaged, glycoproteins, and other peptides; inorganic components include calcium, phosphate, and hydroxide ions (in hydroxyapatite)
Bowman’s capsule
The cuplike structure of the nephron; it collects the globular filtrate and channels it into the proximal convoluted tubule
Bronchi
Tubelike passages for air that connect the trachea to the bronchioles
Bronchioles
Passageways for air that start at the bronchi, dividing into continuously smaller passageways that eventually lead to the alveoli, where gas exchange occurs
Brush-border enzymes
Group of enzymes present on the luminal surface of cells lining the duodenum that break down larger biomolecules into monomers that are able to be absorbed
Bundle of His
Part of the conduction system of the heart; it carries impulses from the AV node to the ventricles
Callus
Area of excessive deposition of keratin in response to repeated strain due to friction
Canaliculi
Small canals connecting lacunae with the bone matrix with Haversian canals, allowing for the flow of nutrients and wastes
Capillary
Small, thin-walled blood vessel where gas, nutrient, and waste exchange occurs between blood and tissues
Capsid
Protein coat surrounding a virus
Cardiac output
Total blood volume pumped by the left ventricle in one minute, found by multiplying the heart rate times the stroke volume
Cartilage
A firm, elastic, translucent connective tissue produced by cells called chondrocytes
Catabolism
The chemical breakdown of complex substances (macromolecules) to yield simpler substances and energy
Cecum
The first part of the large intestine; accepts material flowing through the ileocecal valve and is the site of the appendix
Cell-mediated immunity
Type of immunity that uses cytotoxic chemicals released from cells to cause death of cells that have been infected by viruses
Cell body
Portion of neuron where the nucleus, endoplasmic reticulum, and ribosomes are located; also known as the soma
Cell theory
A fundamental belief in modern biology that all living things are composed of cells, that the cell is the basic functional unit of life, that all cells arise from preexisting cells, and that DNA is genetic material
Central nervous system (CNS)
The brain and spinal cord
Centriole
A small organelle in the cytoplasm oaf animal cells; it organizes the spindle apparatus during mitosis or meiosis
Centromere
The area of a chromosome where sister chromatids are joined; it is also the point of attachment to the spindle fiber during mitosis and meiosis
Centrosomes
Paired cylindrical organelles, located in the cytoplasm, that contain the centrioles
Cerebellum
The section of the mammalian hindbrain that controls muscle coordination and equilibrium
Cerebral cortex
The outer layer of the forebrain, consisting of grey matter; it is the site of higher cognitive functions in humans
Cervix
Lower end of the uterus that marks the transition between the vagina and the uterus
Chemical digestion
Enzymatic cleavage of chemical bonds within foodstuffs, resulting in smaller molecules
Chemotaxis
Movement of cells toward or away from a chemical within the environment
Chiasmata
Sites where crossing over occurs between homologous chromosomes during meiosis
Chief cells
Cells within the stomach that secrete pepsinogen, a zymogen that is converted to its active form, pepsin, by the acidic environment of the stomach
Chondrin
Elastic cartilage matrix substance secreted by chondrocytes
Chondrocyte
A differentiated cartilage cell that synthesizes the cartilaginous matrix
Chromatid
Each of the two chromosomal strands formed by DNA replication in the S phase of the cell cycle; held together by the centromere
Chromosome
A filamentous body found within the nucleus of a eukaryotic cell of nucleoid region a prokaryotic cell, composed of DNA
Chylomicron
Soluble lipid molecule that consists of triglycerides and esterified cholesterol molecules; absorbed into lacteals from the digestive tract
Chyme
Aqueous mixture of food and secretions that leaves the stomach to enter the duodenum
Cilia
Projection from a cell involved in movement of material on the outside of the cell
Circadian rhythm
A behavioral pattern based on a 24-hour cycle, rated to a consistent cycling of hormones such as cortisol and melatonin
Cleavage
A series of mitotic divisions of the zygote immediately following fertilization, resulting in progressively smaller cells with increased nucleus-to-cytoplasm ratios
Clonal selection
Phenomenon in which only B- or T-cells specific to a particular pathogen are activated
Coccus
Spherically-shaped bacterium
Codominance
A genetic effect in which the phenotype of a heterozygote is a reflection of both alleles at a particular locus
Competent
Describes a cell capable of responding to induction signals
Conjugation
The temporary joining of two organisms via a tube called a pilus, through which genetic material is exchanged; a form of sexual reproduction used by bacteria
Connective tissue
Animal tissue composed of cells lying in an extracellular proteinaceous network that supports, connects, and surrounds the organs and structures of the body
Constant region
Portion of an antibody molecule that is not variable and participates in the binding of other immune modulators
Convergent evolution
The process by which unrelated organisms living in a similar environment develop analogous structures
Corona radiata
Layer of cells surrounding an oocyte that aid in the development of the ovum
Corpus luteum
The remnant of the ovarian follicle, which after ovulation continues to secrete progesterone. Its degeneration leads to menstruation; maintains uterine lining during pregnancy
Cortex
The external layer found in many organs of the body, including the brain, adrenal glands, and kidney
Cortical reaction
Release of calcium ions by an ovum after fertilization, resulting in the creation of a fertilization membrane, a structure that prevents fertilization of an ovum by multiple sperm cell
Corticosteroids
Steroid hormones produced in the adrenal cortex, including glucocorticoids (cortisol), mineralocorticoids (aldosterone), and cortical sex hormones
Crossing over
The exchange of genetic material between homologous chromosomes during meiosis
Cyclins adenosine monophosphate (cAMP)
An intracellular second messenger in the signaling cascade initiated by a peptide hormone; synthesized from ATP by adenylate cyclase
Cytokine
Chemical substance that stimulates inflammation and recruits additional immune cells to a specific area
Cytokinesis
The division and distribution of parent cell cytoplasm to the two daughter cells during mitotic and meiotic cell division
Cytoplasm
The fluid and solutes within a cell membrane, external to the nucleus and cellular organelles
Cytotoxic T-cell
T-cell that seeks out infected cells and induces apoptosis in these cells to prevent spread of the pathogen
Deletion
A type of genetic mutation in which some variable amount of DNA is removed
Dendrite
The portion of a neuron that receives stimuli and converts them toward the cell body
Dermis
The layer of skin cells under the epidermis. Contains sweat glands, hair follicles, fat, and blood vessels
Determinate cleavage
Rapid mitotic divisions occurring in an embryo that result in cells with predetermined fates; these cells are only capable of differentiating into certain groups of tissues within an organism
Determination
Designation of a cell within an embryo as having a particular future function
Diaphragm
Thin, muscular structure that divides the thorax from the abdomen and provides the driving force for inhalation
Diaphysis
Cylindrical shaft of a long bone
Diastole
The period of relaxation of cardiac muscle during which the atrioventricular valves open and the ventricles fill with blood
Differentiation
The process by which unspecialized cells become specialized. Involves selective transcription of the genome
Digestion
The breakdown of macromolecular nutrient material via mechanical and chemical means to simple molecular building blocks; this facilitates absorption
Diploid
Having two chromosomes of each type per cell; symbolized by 2n
Direct hormone
Substance secreted into the bloodstream that causes a change in the physiological activity of cells without requiring an intermediary
Directional selection
Selective pressure favor the development of an extreme phenotype that provides a selective advantage; this phenotype emerges as the primary phenotype over time
Disruptive selection
Selection pressure favoring extreme phenotypes over the norm
Divergent evolution
A process of change whereby organisms with a common ancestor evolve dissimilar structures (such as dolphin flippers and human arms)
Dominant
Refers to an allele that requires only one copy for expression
Ductus arteriosus
Fetal structure that shunts blood from the pulmonary artery to the aorta to bypass the developing lungs
Ductos venosus
Shunt from the umbilical vein to the inferior vena data, allowing oxygenated blood returning from the placenta to bypass the liver and enter the systemic circulation
Duodenum
First segment of the small intestine; the contents of the stomach and the pancreatic and bile ducts empty into it; site of digestion and some absorption
Ectoderm
Outermost embryonic germ layer; it gives rise to the skin, nervous system, inner ears, lens of the eye, and other structures
Effector
An organ, muscle, or gland used by an organism to respond to a stimulus
Efferent (motor) neuron
A neuron that transmits nervous impulses from the central nervous system to an effector
Embryo
The early developmental stage of an organism; in humans, the term refers to the first eight weeks after fertilization
Endocrine
A form of cell-cell communication that involves the secretion of hormones into the bloodstream by ductless glands; these hormones then travel to distant locations within the organism to cause a change in cellular expression
Endoderm
Innermost embryonic germ layer; it later gives rise to the linings of the alimentary canal and of the digestive and respiratory organs
Endometrium
Uterine lining that is regenerated each month in preparation for implantation of an embryo; absence of an embryo results in sloughing off of the endometrium in a process known as menstruation
Endoplasmic reticulum
Membrane-bound channels in the cytoplasm that transport proteins and lipids to various parts of the cell
Endothelium
Lining of blood vessels consisting of endothelial cells
Enteric nervous system
Collection of neurons within the gastrointestinal tract that govern peristalsis
Eosinophil
Type of granulocytic leukocyte that largely participates in the immune response against parasites; also involves in the pathogenesis of allergies
Epidermis
The outermost layer of the skin
Epididymis
The coiled tube in which sperm gains motility and is stored after its production in the testes
Epiglottis
The small flap of cartilage that covers the glottis during swallowing, preventing food from entering the larynx
Epinephrine
A hormone synthesized by the adrenal medulla; it stimulates the fight-or-flight response; also a neurotransmitter in the sympathetic nervous system
Epiphyseal plate
Cartilaginous structure in the epiphysis where growth occurs
Epiphysis
Dilated end of a long bone
Episomes
A specialized subset of plasmids capable of integrating into the genome of bacteria under specific circumstances
Epithelium
The cellular layer that covers internal and external surfaces of body structures and cavities
Erythrocyte
Red blood cell; a bi-concave, disk-shaped cell that contains hemoglobin and has no nucleus
Esophagus
Portion of the alimentary canal connecting the pharynx and the stomach
Eukaryote
A unicellular or multicellular organism composed of cells that contain a membrane-bound nucleus and other membrane-bound organelles
Evolution
The changes in the gene pool from one generation to the next cause by mutation, nonrandom mating, natural selection, and genetic drift
Exocrine glands
Glands that release their secretions into ducts (such as the liver and sweat glands)
Expressivity
Varying expression of disease symptoms despite identical genotypes
Extensor
A muscle used in the straightening of a limb
Facultative anaerobes
Prokaryotes that can exist with or without oxygen
Fertilization
Fusion of two gametes
Fertilization membrane
Structure created by the cortical reaction after fertilization of an ovum by a sperm cell; prevents fertilization of an ovum by multiple sperm cells
Fetus
A developing organism that has passed the early developmental stages. In humans, the term refers to an embryo from the ninth week after fertilization until birth
Fibrin
The insoluble protein that forms the bulk of a blood clot
Filial generation
Offspring in a genetic cross; may be supplemented with a subscript to show how many generations out from the parents
Filtration
In the nephron, the process by which blood plasma is forced (under high pressure) out of the glomerulus into Bowman’s capsule
Fitness
Reproductive success of an individual, measured in increased number and survival of offspring
Flagellum
A microscopic, whip-like filament that functions in the locomotion of sperm cells and some unicellular organisms; composed of microtubules
Flexor
A muscle used in the bending of a limb
Follicle
The set of cells surrounding a developing or mature ovum. Secretes nutrients and estrogen and atrophies into the corpus luteum after ovulation
Foramen ovale
Shunt within the fetal heart between the right and left atria that allows circulation to largely bypass the developing lungs
Gallbladder
Organ below the liver that stores bile; contracts in response to stimulation by cholecystokinin, resulting in release of blue into the biliary system and eventually into he duodenum
Gamete
Sperm or ovum; a cell that has half the number of chromosomes of a somatic cell (haploid) and can fuse with another gamete to form a zygote
Ganglion
A mass of neuron cell bodies outside the central nervous system
Gastrula
The embryonic stage characterized by the presence of ectoderm, mesoderm, and endoderm
Gene
The basic unit of heredity; a region on a chromosome that codes for a specific product
Gene pool
All of the alleles for every gene in every individual in a given population
Genetic drift
Variations in the gene pool caused by chance
Genetic map
A diagrammatic representation of a chromosome indicating distance between two genes on a chromosome as determined by recombination frequencies
Genome
An organism’s complete set of chromosomes
Genotype
The genetic composition of an entire organism or in reference to a particular trait
Glomerulus
The network of capillaries encapsulated by Bowman’s capsule. Acts as a filter for blood entering the nephron
Glottis
The opening to the trachea
Golgi apparatus
Organelle that plays a role in the packaging and secretion of proteins and other molecules produced intracellularly
Gonad
Ovary or testis; the reproductive organic which gametes are produced
Gram staining
A process of staining bacterial cells such that cells containing large amounts of peptidoglycan within the cell wall are stained purple, while cells with less peptidoglycan within their cell walls appear pink-red after counter-staining
Granulocyte
Type of leukocyte with cytoplasmic granules that are visible under a microscope, such as neutrophils, basophils, or eosinophils