Biology 241 Topic 4 Flashcards

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1
Q

What is facilitated diffusion?

A

The use of tunnel shaped proteins in the membrane to allow diffusion down the concentratiion gradient

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2
Q

What are 4 characteristics of facilitated diffusion

A

-Each channel is substrate specific
-Does not need ATP (energy)
-[gradient] determines rate
-can be reversed

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3
Q

What uses facilitated diffusion?

A

large polar molecules or ions

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4
Q

Whats the difference between channel proteins and carrier portein in facilitated transport/diffusion?

A

Channel: |o| or }o{ (straight path)

Carrier: \o/ -> |o| -> /o\ (Waits for solute to bind to then changes shape

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5
Q

What is the difference between simple and facilitated diffusion graphed?

A

Facilitated approaches a maximum while simple is a psoitive linear incline

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6
Q

What type of environment do cells live in… and what does mean in terms of the cell?

A

Dilute, the cell needs the to keep the molecules on the inside rather than diffuse towards the environment

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7
Q

How do cells establish a concentration gradient? What does this require?

A

The solutes must move away from equlibrium, thus requiring an energy source

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8
Q

What is Primary Active Transport?

A

When a highly specific protein pump uses ATP to transports a solute against its [gradient] (low to high) and across the membrane.

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9
Q

What is Secondary Active Transport?

A

A highly specific protein that transports solutes up the [gradient] (low to high). Generates power by having a different solute move down its own [gradient]

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10
Q

What is the difference between symporters and antiporters in secondary activde transport?

A

Symporters: Both solutes move in the same direction
Antiporters: Solutes move in opposite directions

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11
Q

What are the forms of Passive transport? (aside osmosis)

A

Simple diffusion and Facilitated Diffusion

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12
Q

What solutes use simple diffusion?

A

Small hydrophobic (non-polar) and small polar (hydrophilic) solutes

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13
Q

What is simple diffusion?

A

Direct diffusion across the phospholipid bilayer down the concentration gradient (high to low)

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14
Q

What does a large concentration gradient cause in terms of simple diffusion?

A

A faster rate of diffusion

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15
Q

Why do phospholipids form bilayers in water?

A

Hydrophobic tails move inwards away from water while the Hydrophilic head move outwards toward the water
E.g.
OOOOOOOOO
|||||||||||||
OOOOOOOOO

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16
Q

What are lipids?

A

Hydrophobic molecules comprised mostly of carbon and hydrogen molecules

17
Q

What are the three Biological lipids?

A

-Triglycerides(Triacylglycerolds)
-Phospholipids
-Sterols

18
Q

What is the function of triglycerides

A

Energy Storage

19
Q

Which 2 Biological Lipids are bulding blocks for the cell membrane

A

Phospholipids and Sterols

20
Q

Fatty acids are the building blocks of which biological lipids

A

Triglycerides and phospholipids

21
Q

What are Fatty Acids comprised of?

A

Hydrocarbons with a Carboxyl group

22
Q

Which one does not have any C=C bonds and which has one or more C=C (C=C stands for carbon carbon double bond):
-Saturated Fatty Acid
-Unsaturated Fatty Acid

A

-Saturated FattyAcid has no C=C
-Unsaturated Fatty Acid has one or more C=C

23
Q

What increases the fluidity of a membrane?

A

-increase tempurature
-more unsaturated fatty acids
-short chains in the fatty acid tails
-cholesterol

24
Q

Why is the Lipid Bilayer considered fluid?

A

Each phospholipid is independant and not attached to one another (able to move freely along the plane of the membrane)

25
Q

What is a Fluid Mosaic Model?

A

Visually demonstrates the structure of the membrane; includes the phospholipid bilayer and protein channels
Fluid reffering to its independant movemennt of phospholipids across the membrane and mosaic reffering to its mulitple parts.

26
Q

What is the difference between a natural unsaturated fatty acid and an unnatural one?

A

Natural: Cis double bond (hydrogens are side by side)

Unnatural: Trans double bond (hydrogens are on opposite sides)

27
Q

What does a Tryglyceride structure look like

A

3 fatty acid tails bound by a glycerol anchor through ester linkage

28
Q

What are phospholipids comprised of

A

Head: Organic molecule, phosphate, glycerol
+
2 fatty acid tails

29
Q

Phospholipids are amphipathic, what does this mean?

A

Has a hydrophobic end and a hydrophilic end

30
Q

What do sterols(cholesterol)do in regards to membrane fluidity?

A

Regulates fluidity, prevents viscosity by preventing them from being too tightly packed and prevents too much fluidity by filling in gaps

31
Q

What is the relationship between membrane fluidity and permeability?

A

Fluid membrane: More solutes can pass (and quicker)
Viscous membrane: Fewer solutes may pass (and slower)

32
Q

Ordering from 1-4, what can diffuse (passively) through a membrane and what cannot

A

1 (diffuse quickly): Non polar molecules (O2, CO2, N2)
2 (diffuse slowly): Small, uncharged polar molecules (H2O, indole, glycerol)
3 (cannot diffuse) : Large, uncharged polar molecules (Glucose, scrose)
4 (cannot diffuse): Ions (Cl-, K+, Na+)

33
Q

How does water cross membranes

A

Through water pores called Aquaporins (only allow H2O)

34
Q

What is diffusion?

A

The tendency dissolved molecules to become evenly distributed [High] to [low]

35
Q

What 2 things do equilibrium result in

A

-The [gradient] is eliminated
-Lower energy state

36
Q

What is a condition of diffusion

A

Only works if solute can pass through the bilayer freely

37
Q

What is osmosis?

A

If the solute cannot move, water will move from low [solute] to high [solute]

38
Q

What are the 3 states of tonicity in regards to osmosis

A

Hypertonic- [solute] is higher in solution, cell shrivels
Hypotonic- [solute ] is lower in solution. cell swells and possibly bursts
Isotonic- balanced, cell does not change shape