biological therapy for SZ Flashcards
what are the 2 classes of antipsychotic drugs
typical drugs
atypical drugs
name the drug that is a typical drug
chlorpromazine
what does chlorpromazine work on
works on hyperdopaminergia by reducing the actions of dopamine by blocking the postsynaptic receptor sites
so decreased symptoms (e.g: hallucinations) and is a sedative
acts as a dopamine antagonist so dopamine is broken down and reabsorbed into the presynaptic neurone
can antipsychotics be used for short term or long term use
antipsychotics can be used for short term and long term use
why can chlorpromazine act as a sedative
chlorpromazine acts as a sedative due to its linked effects on histamine receptors. The drug is used to calm SZ patients
why might chlorpromazine be used on patients arrival to a psychiatric hospital
chlorpromazine is used on initial admittance to hospital if patients are very anxious
what are the 2 types of typical antipsychotics
clozapine
risperidone
what is the role of atypical antipsychotics
made to improve the effectiveness of drugs in supressing the symptoms of psychosis and minimise side effects
why is clozapine taken and what is the role of clozapine
taken if typical drugs fail, thought to work on dopamine serotonin system, glutamine receptors and improves mood so can reduce suicide risk
why is risperidone taken and what is the role of risperidone
risperidone, less side effects than clozapine binds to dopamine and serotonin sites
what are the 3 ways to administer chlorpromazine
- tablets
- syrup
- injection
what is the dosage of chloropromazine
oral administration up to 100mg daily
dosage starts low and increases gradually
what 2 ways can clozapine be administered
tablets
syrup
what is the dosage of clozapine
daily dosage 300-450 mg
what are the ways to administer risperidone
- tablets
- syrup
- injection (lasts for 2 weeks)
