biological therapy Flashcards
drug therapy
-assumes the genetic explanation
-used to reduce the intensity of symptoms
typical antipsychotics
-dopamine agonists (block dopamine receptors)
-block all dopamine activity (cause negative symptoms and Parkinson’s symptoms)
-have a sedative effect (makes brain malleable)
example of typical
chlorpromazine (limit symptoms of psychosis but have side effects)
atypical antipsychotics
-bind to dopamine, serotonin and glutamte receptors (improve cognitive function and reduce depression)
-give to those with high risk of suicide
example of atypical
-clozapine (same effect of psychosis with less die effects)
-risperidone (effective with less side effects)
serious side effects
-dizziness, agitation, sleepiness
-tardive dyskinesia (involuntary facial movements)
-pseudoparkinsons (imitate Parkinsons)
explain - can be reduced by king fewer drugs but can worsen SZ symptoms
evidence for moderate effectiveness
-thornley et al (2003) chlorpromazine (typical) was associated with better functioning and reduced symptom severity
-meltzer (2012) clozapine (atypical) was more effective than others and effective in 30-50% of treatment-resistant patients
-long term effects aren’t discussed (successful trials published multiple times to exaggerate positive results)
reductionism
-only take into account the biological aspects of SZ (dopamine and genetics)
-dont go into depth about the environmental factors that may cause SZ