Biological Rhythms and Sleep Flashcards
Circadian Rhythm + Example
Occur about once a day.
Eg. Going to sleep/waking up, fluctuation of body temp
Infradian Rhythm + Example
Occur less than once a day.
Eg. Menstrual cycle
Endogenous pacemakers
Internal factors that influence biological rhythms
Eg suprachiasmatic nucleus
Exogenous zeitgabers
External/environmental factors that regulate timing of biological rhythms
Eg. Daylight or alarm clocks
Endogenous pacemakers in sleep wake cycle
Suprachiasmatic nuclei
How does the SCN work
SCN sends signal to PINEAL GLAND to increase or decrease production of MELATONIN.
Zucker
Found that if SCN cells are destroyed then sleep is distrupted.
Suggests SCN plays causal role in maintaining sleep-wake cycle.
Inouye and Kawamura
Kept SCN tissue from animals alive in an organ culture seperate from rest of the brain. Even with no light, the cell showed a circadian rhythm.
Suggests SCN had internal circadian rhythm.
Ralph
Took SCN from mutant golden hamster with 20hr rhythm and put it in a normal hamster on 24hr cycle. Normal hamster showed shorter rhythm.
SCN plays a role in determining length of the rhythm.
Siffre
Lived in a cave for 6 months away from exogenous zeitgabers so his biological clock was ‘free running’. Settled on a 25 hour cycle.
Suggests exog and endog interact.
Skene
Found that totally blind people have disrupted sleep wake cycles that do not fit 24 hour cycle.
Suggests external zeitgabers maintain and control the cycle.
Folkard
Found that 11/12 people could not sleep properly on 22hrs cycle even though they thought they were on 24hrs.
Suggests endog pace control our sleep wake cycle.
How does light influence the sleep/wake cycle?
Low levels of light»detected by photoreceptors in retina»suprachiasmatic nuclei»pineal gland»melatonin released»reduced brain activity»sleepiness
DeCoursey
Deactivated SCN in 30 chipmunks and after 80 days significantly more of these chipmunks had been killed.
Suggests that they were more likely to be awake and moving in burrows.
Practical implications of Ez and Ep research
Introducing melatonin tablets to increase levels of meletonin and make you feel sleepier.
Nature/Nurture argument
Ep - Nature
Ez - Nurture
Interact with one another