Biological Molecules 1.1-1.3 Flashcards

1
Q

What’re biological molecules?

A

molecules made and used by living organisms e.g. Carbohydrates, Proteins, Lipids, DNA, ATP, Water, Inorganic Ions

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2
Q

What are the building blocks for carbohydrates called?

A

Monosaccharides

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3
Q

Monomers

A

The smaller units from which larger molecules are made

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4
Q

Polymers

A

Molecules made up from a large number of monomers joined together

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5
Q

Examples of monomers

A

Monosaccharides
Amino acids
Nucleotides

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6
Q

Condensation reaction

A

Joins two molecules together with the formation of a chemical bond and involves the elimination of a molecule of water

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7
Q

Hydrolysis reaction

A

Breaks a chemical bond between two molecules and involves the use of a water molecule in

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8
Q

Monosaccharide

A

The monomers from which larger carbohydrates are made

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9
Q

Name some monosaccharides

A

Glucose
Galactose
Fructose

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10
Q

A condensation reaction between two monosaccharides forms

A

A glycosidic bond

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11
Q

Glycosidic bond

A

Forms from a condensation reaction between two monosaccharides

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12
Q

Name some disaccharides

A

Maltose
Sucrose
Lactose

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13
Q

How’s maltose formed

A

The condensation of two glucose molecules

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14
Q

How’s sucrose formed

A

The condensation of a glucose molecule and fructose molecule

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15
Q

How’s lactose formed

A

The condensation of a glucose molecule and a galactose molecule

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16
Q

Two glucose isomers

A

Alpha

Beta

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17
Q

Alpha glucose

A

H

OH

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18
Q

Beta glucose

A

OH

H

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19
Q

Polysaccharide

A

Formed by the condensation of many glucose units

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20
Q

What are polysaccharides

A

carbohydrates
− made of a long chain of monosaccharides joined by condensation reaction/glycosidic ​bonds
− 3 examples: Starch, Glycogen, Cellulose

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21
Q

Name polysaccharides

A

Glycogen
Starch
Cellulose

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22
Q

How’s glycogen formed

A

The condensation of alpha glucose

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23
Q

How’s starch formed

A

The condensation of alpha glucose

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24
Q

How’s cellulose formed

A

The condensation of beta glucose

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25
Alpha glucose polysaccharides
Starch and glycogen
26
A beta glucose polysaccharide
Cellulose
27
Carbohydrates
Most are polymers Made form monomers called monosaccharides All contain elements C H O
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Two groups of carbohydrates
Sugars | Polysaccharides
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Two sugar groups
Monosaccharide | Disaccharide
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Two polysaccharide groups
Storage | Structure
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Polysaccharides used for storage
Glycogen | Starch
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Polysaccharides used for structure
Cellulose | Chitin
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Test for reducing sugars
Benedict’s Add 2 cm³ of the sample to a test tube Add 2 cm³ of Benedict’s solution to this test tube. Benedict regrant is an alkaline solution of copper sulphate Heat in a water bath at a minimum of 70°C After three minutes record the colour of the solutions. The colour will change from blue to brick red copper oxide.
34
Test for non reducing sugars
Add 2 cm³ of the sample to a test tube Add dilute hydrochloric acid, and heat in gently boiling water for five minutes. The acid will hydrolyse any disaccharide present (breaks the glycosidic bonds) Add sodium hydrogen carbonate to then neutralise the acid Retest the solution using Benedicts reagent. If the test is negative for any sugar at all, blue colour will remain. If the red precipitate is formed, then a non-reducing sugar would have been present in the original sample
35
Test for starch
Iodine solution Add 2cm3 of the sample to a spotting tile/ test tube Add 2 drops of iodine solution A colour change from orange/brown to blue/black shows that starch is present
36
Reducing sugar
A sugar that can donate electrons to another chemical called Benedict’s reagent, ‘reducing’ it, causing it to change colour
37
Name reducing sugars
All monosaccharides (glucose, galactose, fructose) Maltose Lactose
38
What’s Starch
Polysaccharide | Made up of Chains of a-glucose monosaccharides linked by glycosidic bonds formed by condensation reactions
39
Starch main role
Storage
40
Starch’s structure for function
Insoluble so can’t draw water into cell by osmosis Large and insoluble so cannot diffuse out of cell Compact so lots of it can be stored in a small area When hydrolysed it forms alpha glucose which can be easily transported and used in respiration The branched form has many ends, each can be acted on by enzymes simultaneously meaning that glucose monomers are released very rapidly
41
Where is starch found
Plants | Seeds and storage organs
42
What is glycogen
Polysaccharides found in animals Small chains with many branches Stored as small granules in muscles and liver Alpha glucose chains linked by glycosidic bonds
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Main role of glycogen
Storage
44
Glycogen structure for function
Insoluble so doesn’t draw water into cells by osmosis Being insoluble it doesn’t diffuse out of cells Compact, so a lot of it can be stored in a small space More branched than starch, so has more ends that can be acted on simultaneously by enzymes. It is therefore more rapidly broken down to form glucose monomers for respiration
45
What is Celulose
Made of beta glucose monomers Has straight unbranched chains These chains run parallel to each other, allowing the hydrogen bonds to form cross linkages between adjacent chains The overall number of the hydrogen bonds makes a considerable contribution to strengthening Celulose The cellulose molecules molecules are grouped together to form microfibrils which are arranged in parallel groups called fibres
46
Cellulose structure
B glucose molecules in long chains parallel Hydrogen binds forming cross bridges Unbranched chains Cellulose chain has adjacent glucose molecules rotated by 180 degrees Allows hydrogen bonds to be formed between (-OH) groups on adjacent parallel chains that help to give cellulose its structural stability
47
Celulose main role
Structure
48
cellulose structure for function
Prevents the cell from bursting as water enters it by osmosis Does this by exerting an inward pressure that stops any further influx of water Long unbranched chains run parallel to each other and are cross-linked by hydrogen bonds which adds collective strength these molecules are grouped to form microfibrils which in turn group to form fibres all of which provides yet more strength
49
How to remember lipids roles
WIMPE
50
Lipids waterproofing
Insoluble in water
51
Lipids insolation
Helps retain body heat
52
Lipids membranes
Contributes to flexibility of cell membranes
53
Lipids protection
Around delicate organs
54
Lipids energy
When oxidised, releases two times quantity of energy as carbohydrates
55
Two lipids groups
Triglycerides | Phospholipids
56
Triglycerides two groups
Fats | Oils
57
Difference between fats and oils
Both triglycerides Fats are solid at room temp oils are liquid at room temp
58
Forming triglycerides
1 glycerol + 3 fatty acids | Makes 1 triglyceride and 3H2O
58
Two types of triglycerides
Saturated and unsaturated fat
59
Glycerol formula
C3H8O3 -OH Group ``` H | H-C-OH | H-C-OH | H-C-OH | H ```
60
Fatty acid formula
RCOOH- O || HO-C-R
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Triglyceride formula
``` H O | || H-C-O-C-R | O | || H-C-O-C-R | O | || H-C-O-C-R | H ```
62
Triglyceride structure related to function
High ratio of energy storing C-H bond to carbon atoms, therefore is an excellent source of energy Low mass to energy ratio, makes them good energy storage molecules. Beneficial as reduces the mass animals have to carry as they move Large, non polar molecule, meaning they’re insoluble in water. Don’t effect water potential/osmosis in cells High ratio of hydrogen to oxygen atoms- release lots of water therefore when oxidised Double bonds in polyunsaturated fatty acids makes the molecule bond. They cannot pack together so closely. Liquid at room temp
63
Phospholipid
Phospholipids are a class of lipids that are a major component of all cell membranes. They can form lipid bilayers because of their amphiphilic characteristic. The structure of the phospholipid molecule generally consists of two hydrophobic fatty acid "tails" and a hydrophilic "head" consisting of a phosphate group.
64
Phospholipid structure
Glycerol, 2 fatty acids and phosphate Hydrophilic phosphate Head and hydrophobic fatty acid tails
65
Phospholipid structure related to function
Polar molecules, meaning that in an aqueous environment, phospholipid molecules form a bilayer within cell-surface membranes. So hydrophobic barrier is formed between the inside and outside of a cell Hydrophobic phosphate head helps to hold the cell membrane together Structure allows them to form glycolipids by combining with carbohydrates within the cell surface membrane. These glycolipids are important in cell recognition
66
What binds join fatty acids to glycerol
Ester bonds
67
Saturated fatty acid structure
No double C bond No kink Solid at room temp
68
Monounsaturated fatty acid structure
One double C bond Kink Liquid at room temp
70
Polyunsaturated fatty acid
Two double C bonds
71
Test for lipids
``` Emulsion Test Grease free tube 2cm3 of sample and 5cm3 ethanol Shake to dissolve any lipid present Add 5cm3 water and gently shake Cloudy white colour indicates presence of lipid ```
72
What causes emulsion
Light passing through the emulsion is refracted as it passes from oil droplets to water droplets- makes it look cloudy
73
Where are Ester bonds formed
Between fatty acid and glycerol in a condensation reaction | Triglyceride and phopolipid
74
Lipids WIMPE
``` Water proofing Insulation Membrane Protections Energy ```
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Monosaccharide formula
C6H12O6
76
Disaccharide formula
C12H22O11
77
Butter
Solid at room temp | saturated fat
78
Oil
Liquid at room temp | Unsaturated fat
79
Why is butter solid at room temp whilst vegetable oil is liquid
Butter- saturated fat (molecules can pack closely together because they have no kink, so it’s easier to solidify) Liquid- unsaturated (has kink so molecules are less likely to pack tog)
80
Hydrophilic head phospholipids
Water loving Interacts with water, not fat Is the phosphate molecule
81
Hydrophobic tail phospholipids
Hates water Interacts with fat not water Are the fatty acids
82
Isomer
When two molecules has the same amount of each atom but they have a different arrangement E.g. a and B glucose
83
Guidelines advise people to reduce their intake of saturated fats to reduce the risk of
Cardiovascular disease
84
What’s starch and glycogen used for in plants and animals
Energy | Converts into glucose (hydrolysis)
85
Starch is made up of what two polymers (composed of glucose units)
Amylose (linear) | Amylopectin (branched)
86
What’s glycogenolysis
process by which glycogen, the primary carbohydrate stored in the liver and muscle cells of animals, is broken down into glucose to provide immediate energy and to maintain blood glucose levels during fasting.
87
Why is glucose stored as polysaccharides
Glucose is soluble in water Would effect water potential of any fluid it’s dissolved in Can’t be stored However polysaccharides are insoluble in water
88
Which has more branches | Starch or glycogen
Glycogen Animals have higher need for energy than plants