Biological Materials Flashcards
What three things do bones contain?
- Water (25-30%)
- Collagen (30% of dry weight)
- Minerals (70% of dry weight)
Bone is capable of withstanding what?
Loads six times those experienced in normal life
A specialised form of connective tissue, bone consists of many cells (osteocytes), which have what three properties?
Light
In a collagen matrix
Packed with minerals
Biomechanically what are the two types of bones?
Cortical
(Thick layer outside the bone)
Trabecular
(Layered maze like mass within the bone)
The two main forms of bone damage comes in what forms?
- Fractures, which can be either traumatic (usually a one-off impact)
- Fatigue-induced (these are often called stress fractures although this term is slightly misleading).
A diaphyseal impaction fracture is caused by what load?
Axial compression
A transverse fracture is caused by what load?
Bending
Cortical bone weaker in tension than compression, so bone under tension fails first.
Failure mechanism is break propagation perpendicular to bone’s long axis, from surface layer inwards
A spiral fracture is caused by what load?
Torsion
A oblique transverse is caused by what load?
Axial compression
Bending
Torsion
Cells are widely separated within a fibrous, organic matrix which may:
Appear (but isn’t) structureless as in rigid hyaline cartilage, Contain more connective tissue fibres in the matrix (e.g. fibrocartilage)
Cells (chondrocytes) account for less than what percentage of the tissue volume?
10%
The organic matrix of cartilage consists of what?
Collagen fibrils within a proteoglycans solution
What is a tissue made up of?
60-87% is made up of
Water
Inorganic salts
Small quantities of matrix proteins / glycoproteins / lipids
What does a cartilage mechanical properties depend on?
The direction of loading (anisotropic)
Cartilage shows what three typical viscoelastic behaviours?
- Initial deformation followed by more gradual increase
- Returns to initial shape on load removal (hysteresis)
- Prolonged standing causes creep of intervertebral discs (hence shortening of the body’s overall height)