Biological Evaluation - Structural Abnormalities Flashcards
Evaluate the repeatability of the findings…
Robert McCarley and colleagues (1999) stated that the presence of enlarged ventricles is the most reliable finding in research, while also confirming the link between cortical atrophy and schizophrenia
Stated that factors such as age, sex, and severity of symptoms can affect the prevelence and pattern of brain abnormalities, in addition to how patients are assessed
Evaluate whether abnormalities is the cause or effect…
Unclear whether it is a cause or effect as environmental influences can impact brain tissue
Kenneth Lyon et al (1981) found that as doses of antipsychotics increased the density of brain tissue decreased, suggesting that antipsychotics are the cause of structural abnormalities
Evaluate how abnormalities are not linked to schizophrenia…
Abnormalities are also found in those without schizophrenia
Paul Rey et al (1998) found that bipolar disorder and schizophrenia have overlapping symptoms, indicating that the way that these two conditions are classified needs to be reviewed or that both conditions have similar causation
Evaluate if abnormalities are neurodegenerative or neurodevelopmental…
Mathalen et al (2003) claimed that abnormalities are caused by a combination neurodevelopmental factors which impair cortical development, making them more susceptible to neurodegenerative processes
Neurodevelopmental - hinder healthy brain development
Neurodegenerative - loss of cortical tissue
