Biological DataBase Flashcards

1
Q

what are the characteristics of Primary sequence databases ?

A

Primary sequence databases are archival in nature.
They contain raw sequence data (experimental results)
with some interpretation and explanation, but the data
are not curated. There are also redundancies in the pri-
mary databases—that is, the same sequence might be
submitted by different laboratories, different names.

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2
Q

what is an accession number

A

when you needs to submit the sequence the database will give you an accession number that must be provide within the publication

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3
Q

how to submit data to an DB

A

During sequence submission, the submitter has to
provide some relevant information about the sequence,
such as the name of the mRNA/gene, the source,
annotation, open reading frame, and putative translation product.During submission of a sequence, the submitter
may choose to release the sequence information to the
public at a later date (many months later than the
actual date of submission to the database) by giving
instruction during submission. The information for the submission must be provided in a flatfile format.

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4
Q

What is the RefSeq database?

A

RefSeq is a synthesis of all the information obtained and integrated from multiple sources. The RefSeq database is a collection of non-redundant, curated, and annotated sequences. RefSeq provides a single record for each natural biological molecule (DNA, RNA, or protein) for major organisms ranging from viruses to bacteria to eukaryotes.

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