Biologic tissues Flashcards
Example of isometric contraction
Pushing against a wall
Example of isotonic contraction
Biceps curl (concentric vs eccentric)
What are the slow muscle fibers?
Type 1 oxidative (slow red ox)
What is the order of muscle fiber recruitment?
Type 1 (slow twitch), Type 2 (a then b, fast twitch)
What is scleraxis?
Transcription factor important for ligaments+tendons
Where do kid ligaments avulse?
Between mineralized and unmineralized layers
What is decorin?
Proteoglycan
regulates collagen fiber diameter in tendons
forms cross links in collagen
When does a healing tendon regain strength?
original strength at 21 days
max strength at 6 months
What gene controls chondrocyte differentiation?
Sox-9
Which synovial cells produce synovial fluid?
Type B
Which nerve layer provides most strength/elasticity?
Perineurium (single fascicle)
Endoneurium = single axon Epineurium = group of fascicles
What codes for adipocytes
PPar Gamma
Articular cartilage layers
Superficial (tangential) Transitional (Intermediate) Deep (basal) Tidemark Subchondral bone Cancellous bone
Where chondrocyte progenitor cells are
Superficial layer
Cartilage changes with OA
INCREASED
Water, chondroitin sulfate
DECREASED stiffness
